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Bioprocess Development Jobs in California (NOW HIRING)

Orca Bio

Associate, Bioprocess Development

Menlo Park, CA · On-site

$75K - $105K/yr

Bridge development and manufacturing activities by translating process learnings into robust, executable procedures, batch records, and tech transfer documentation. * Perform development and ...

Orca Bio

Associate, Bioprocess Development

Menlo Park, CA · On-site

$75K - $105K/yr

Bridge development and manufacturing activities by translating process learnings into robust, executable procedures, batch records, and tech transfer documentation. * Perform development and ...

PBS Biotech

Research Associate

Camarillo, CA · On-site

We are seeking a full-time, highly motivated Research Associate to join our growing bioprocess R&D team. This position is an invaluable opportunity to gain experience working with cutting-edge ...

PBS Biotech

Research Associate

Camarillo, CA · On-site

We are seeking a full-time, highly motivated Research Associate to join our growing bioprocess R&D team. This position is an invaluable opportunity to gain experience working with cutting-edge ...

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All JobsBioprocess Development JobsBioprocess Development Jobs in California

Bioprocess Development information

See California salary details

$28.6K

$52.7K

$79.9K

How much do bioprocess development jobs pay per year?

As of Sep 1, 2026, the average yearly pay for bioprocess development in California is $52,718.00, according to ZipRecruiter salary data. Most workers in this role earn between $41,900.00 and $59,200.00 per year, depending on experience, location, and employer.

What is bioprocess development?

Bioprocess development is the process of designing, optimizing, and scaling up methods to produce biological products such as vaccines, antibodies, enzymes, or biofuels using living cells or their components. This field involves activities like selecting the best microorganisms or cell lines, optimizing growth conditions, and developing purification steps to ensure product quality and quantity. Bioprocess development is essential in industries like pharmaceuticals, biotechnology, and agriculture for bringing laboratory discoveries into commercial-scale production. Professionals in this area work closely with research scientists and engineers to translate lab-scale processes into manufacturing protocols. The ultimate goal is to create efficient, cost-effective, and reproducible production methods for biologics.

What are the key skills and qualifications needed to thrive in bioprocess development?

To thrive in Bioprocess Development, you need a strong background in biology, chemistry, and process engineering, typically supported by a degree in biotechnology, biochemical engineering, or a related field. Familiarity with bioreactors, cell culture techniques, analytical instrumentation, and regulatory standards such as GMP is essential. Critical thinking, problem-solving, and effective collaboration are vital soft skills for optimizing processes and addressing complex production challenges. These skills ensure efficient scale-up, quality control, and innovation in the development of biologics and other bioproducts.

What are some typical challenges faced in a bioprocess development role, and how are they addressed?

Professionals in Bioprocess Development often encounter challenges such as optimizing process parameters for scalability, maintaining product consistency, and troubleshooting unexpected variability during production runs. To address these, teams rely on rigorous experimental design, data analysis, and close collaboration with upstream and downstream processing teams. Effective communication and adaptability are crucial, as protocols may need rapid adjustment in response to new findings or regulatory requirements. Continual learning and cross-functional teamwork are key to overcoming these challenges and ensuring successful process development.

What is the difference between Bioprocess Development vs Bioprocess Manufacturing?

AspectBioprocess DevelopmentBioprocess Manufacturing
CredentialsDegree in Biotechnology, Bioengineering, or related fieldsSimilar credentials, often with additional certifications in GMP or quality assurance
Work EnvironmentLaboratory and pilot plant settings focused on process design and optimizationProduction facilities focused on large-scale manufacturing
Industry UsageEarly-stage process design, scale-up, and validationLarge-scale production, process execution, and quality control

Bioprocess Development focuses on designing and optimizing processes in labs and pilot plants, while Bioprocess Manufacturing involves large-scale production and process execution. Both roles require similar educational backgrounds but differ in their focus and work environment.

What are popular job titles related to Bioprocess Development jobs in California?

For Bioprocess Development jobs in California, the most frequently searched job titles are:

What job categories do people searching Bioprocess Development jobs in California look for?

The top searched job categories for Bioprocess Development jobs in California are:

What cities in California are hiring for Bioprocess Development jobs?

Cities in California with the most Bioprocess Development job openings:

Bioprocess Development jobs near you
Infographic showing various Bioprocess Development job openings in California as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 16% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $52,718 per year, or $25.3 per hour.

Associate, Bioprocess Development

Menlo Park, CA

Orca Bio
Pharmaceutical and Medicine Manufacturing • 51 - 200 employees
Learn more about Orca Bioexternal

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 15 days ago

Job description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

Position Summary:

You will focus on developing a process for antibody and antibody conjugate manufacturing, and facilitating tech transfer. You will jointly manage a GMP clean room in Menlo Park, CA, including equipment maintenance, inventory, logbook management and so on. You will perform process development and engineering runs in a GMP environment, contribute to process design, troubleshooting, scale-up/scale-out, assay development, and technology transfer to advance Orca’s clinical pipeline from first-in-human through commercialization. This role collaborates closely with members of the manufacturing, quality, facilities, and supply chain teams.

Essential Duties & Key Responsibilities:
  • Bridge development and manufacturing activities by translating process learnings into robust, executable procedures, batch records, and tech transfer documentation.
  • Perform development and engineering runs according to written procedures in a GMP environment.
  • Perform investigations on process & product deviations for continuous process improvement.
  • Help to manage a GMP clean room following Orca internal procedures. Share responsibility for equipment maintenance and calibration, inventory, environmental monitoring, and logbook management.
  • Perform experiments and assays which increase process understanding and control.
  • Help to perform stability and formulation studies.
  • Collaborate with external vendors and internal teams to design and implement novel technologies for manufacturing, development, and tech transfer.
  • Support continuous improvements of records and follow the operating procedure with strong attention to details.
  • Maintain detailed records of experiments. Practice good data management and documentation habits.
  • Organize and present data in a manner that is easily understood by other team members in lab notes, reports, and presentations.
  • Closely collaborate with Orca teams across manufacturing, quality control, quality assurance, analytical development, and others.
Required Qualifications:
  • Bachelor’s degree in Chemistry, Chemical Engineering, Biotechnology, Biochemistry, or related field with 2-5 years of experience in process sciences, or manufacturing science and technology experience.
  • Master’s degree in one of the above fields with 1-3 years of process sciences or manufacturing science and technology experience preparing biologics.
  • Willingness to work in a BSL-2 environment and handle human blood samples
  • Willingness to learn flow cytometry and cell staining techniques for analysis of cell populations. Prior experience is a plus.
Preferred Qualifications:
  • Experience with protein expression and purification workflows
  • Experience with techniques for protein characterization
  • Competence in aseptic technique and mammalian cell culture
  • Experience preparing and characterizing protein conjugates
  • Familiarity with FPLC instruments
  • Experience preparing and analyzing plasmid DNA and performing transformations and transfections
Professional Qualities:
  • Clear and effective communicator and listener
  • Detail oriented and organized
  • Writes clearly and concisely
  • Takes ownership and responsibility for tasks
  • Strives to learn new things
  • Comfortable working in both exploratory development settings and highly controlled GMP manufacturing environments
Travel Requirements:
  • Travel to Orca’s Sacramento manufacturing facilities as-needed.
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
 
Who we are
 
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
 
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
 
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
 
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
 
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
 
Notice to staffing firms
 
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.