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Biomarker Jobs (NOW HIRING)

Manage biomarker related operational work for clinical trials and programs. Act as biomarker operation representative to lead/participate in cross-functional activities and initiatives. Act as key ...

Manager, Biomarker Operations

Cambridge, MA ยท On-site

$109K - $174K/yr

The Role Moderna is seeking a Biomarker Operations Manager to support biomarker and clinical teams across its clinical trials as well as with external biorepositories, assay laboratories and CROs.

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Biomarker information

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$49K

$203.5K

$400K

How much do biomarker jobs pay per year?

As of Sep 4, 2026, the average yearly pay for biomarker in the United States is $203,468.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,500.00 and $400,000.00 per year, depending on experience, location, and employer.

What is a biomarker?

A Biomarker job involves researching and identifying biological indicators (biomarkers) that help diagnose diseases, track disease progression, or monitor treatment responses. Professionals in this field work in pharmaceuticals, biotechnology, or healthcare, using advanced laboratory techniques and data analysis to validate biomarkers for clinical use. They collaborate with scientists, clinicians, and regulatory teams to ensure biomarkers meet medical and regulatory standards. This role is crucial in developing precision medicine, improving patient care, and advancing drug development.

What skills and qualifications are needed to thrive as a biomarker?

To thrive as a biomarker scientist, you need a strong background in molecular biology, biochemistry, or related biomedical sciences, often supported by an advanced degree (MS or PhD). Familiarity with laboratory techniques such as ELISA, PCR, mass spectrometry, and data analysis software like R or SAS is essential. Critical thinking, attention to detail, and effective communication help biomarker scientists excel in both independent and collaborative research settings. These skills ensure accurate identification and validation of biomarkers, which are crucial for advancing diagnostics, drug development, and patient care.

What typical challenges do biomarker scientists face in their daily work?

Biomarker scientists often encounter challenges related to variability in biological samples, stringent validation protocols, and the complex interpretation of large or multidimensional datasets. Overcoming these obstacles requires a meticulous approach to experimental design, robust data analysis, and effective troubleshooting skills. Teamwork is also essential, as biomarker scientists regularly collaborate with clinicians, bioinformaticians, and regulatory experts to ensure research breakthroughs translate into real-world patient benefits. Developing resilience and adaptability helps professionals stay effective despite shifting project requirements or unforeseen experimental hurdles.

How to become a clinical biomarker lead?

To become a clinical biomarker lead, candidates typically need a strong background in biomedical sciences, such as a PhD or master's degree in biology, chemistry, or related fields. Relevant experience includes working in clinical research, biomarker development, or diagnostics, along with skills in data analysis and regulatory compliance. Certifications in clinical research or laboratory management can also enhance prospects for leadership roles in this field.

What does a biomarker do?

A biomarker is a biological molecule, gene, or characteristic that indicates a normal or abnormal process, or a response to a treatment. Biomarkers are used in research and clinical settings to diagnose diseases, monitor health conditions, and guide treatment decisions. Biomarker professionals often analyze biological samples using laboratory techniques and may require knowledge of biochemistry and data analysis.

What does a biomarker scientist do?

A biomarker scientist researches and develops biological markers used to detect or monitor diseases, conditions, or responses to treatment. They analyze biological samples using techniques like molecular biology, biochemistry, and data analysis, often working in laboratories or research settings. Their work supports diagnostics, drug development, and personalized medicine.
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Infographic showing various Biomarker job openings in the United States as of August 2026, with employment types broken down into 97% Full Time, 1% Part Time, and 2% Contract. Highlights an 76% Physical, 6% Hybrid, and 18% Remote job distribution, with an average salary of $203,468 per year, or $97.8 per hour.

Principal Scientist II, Translational Biomarker Strategy Lead

Novartis Group Companies

Cambridge, MA โ€ข On-site

Other

Retirement

Posted 26 days ago


Job description

Job Description Summary

Novartis Biomedical Research is seeking a highly motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic advisor on DAx project teams.
This role will lead the development and execution of preclinical and translational biomarker strategies from target validation through development candidate nomination and early clinical planning. The Biomarker Strategy Lead will partner closely with Biology, In Vitro, In Vivo, Data Science and Biomarker Development to ensure biomarker plans are aligned with key program decisions and support target engagement, pharmacodynamic assessment, patient stratification, and translational decision-making.
The successful candidate will act as the single point of contact for biomarker strategy within assigned DAx programs, integrating scientific, technical, operational, and external capabilities to deliver execution-ready biomarker plans that enable efficient progression of the portfolio.


Job Description

Major accountabilities:

  • Lead development of stage-appropriate preclinical and translational biomarker strategies for DAx programs from target validation through early clinical development readiness.
  • Serve as the biomarker representative and single point of contact on assigned DAx project teams.
  • Define biomarker hypotheses, context of use, evidence requirements, and decision criteria aligned with program milestones.
  • Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships.
  • Partner across Biology, In Vitro, In Vivo, Data Science, Preclinical Safety, Quantitative Sciences, Translational Medicine, and Biomarker Development to align biomarker activities and execution.
  • Generate translational evidence linking target biology, pharmacology, and biomarkers to support key portfolio decisions.
  • Drive external collaborations and leverage innovative technologies, datasets, and human sample resources to strengthen biomarker strategies and research-to-development transition.

Minimum Qualifications

  • PhD, MD, PharmD, or equivalent in biology, pharmacology, immunology, translational medicine, molecular biology, or related discipline.
  • 7+ years of experience in translational research, biomarker strategy, biomarker discovery, or drug development within the pharmaceutical or biotechnology industry.
  • Demonstrated experience developing biomarker strategies supporting drug discovery and development programs.
  • Strong understanding of biomarker applications including target engagement, pharmacodynamics, patient stratification, disease activity, and mechanism-based biomarkers.
  • Experience leading cross-functional matrix teams and influencing scientific strategy without direct authority.
  • Excellent communication, presentation, and stakeholder management skills.

Rewards

At Novartis,we'recommitted to reimagining medicine together - and rewarding the people who make it happen.

The rewards of being part of our team go far beyond base pay and incentives.We also offer a variety of competitive benefits inkindto help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeingresourcesand global recognition programs. In addition, we provide flexible and hybrid working options, where possible, anda minimum of14 weekspaid parental leave.

Expected Annual Base Salary Range for role:

  • USA: 114,100.00 - 211,900.00 USD Annual

The salary offered isdeterminedbased on gender-neutralobjectives, such as relevant skills,competenciesand experiencein accordance withthe Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Further details will be provided during the application process.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse,equitableand inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.

Readourbrochureto learn more about our global total rewards offering:https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf

Note: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the applicationprocess.

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Why Novartis:Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating,supportingand inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards:Read our handbook to learn about all the wayswe'llhelp you thrive personally and professionally:https://www.novartis.com/careers/benefits-rewards


EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.


Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.


Salary Range

$114,100.00 - $211,900.00


Skills Desired

Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Curious Mindset, Data Analysis, Detail-Oriented, Drug Development, Ethics, Gene Therapy, Immunology, Inventory Management, Machine Learning (ML), Medical Research, Molecular Biology, Python (Programming Language), Science