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Biomarker Jobs (NOW HIRING)

Integrated Resources INC

Biomarker Scientist

Andover, MA · On-site

$35.75 - $44.75/hr

A position is available for a skilled cell biologist/immunologist to join a state-of-the-art cellular biomarker-biomeasures laboratory in PDM, Andover. Expertise in cellular and functional assays ...

PSG Global Solutions

Biomarker Scientist

New Haven, CT

$35.50 - $44.50/hr

Primary Responsibilities: * Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external ...

BeiGene, Inc.

Senior Project Manager, Clinical Biomarker

$140K - $185K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Manage biomarker related operational work for clinical trials and programs. Act as biomarker operation representative to lead/participate in cross-functional activities and initiatives. Act as key ...

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How much do biomarker jobs pay per year?

As of Aug 14, 2026, the average yearly pay for biomarker in the United States is $203,468.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,500.00 and $400,000.00 per year, depending on experience, location, and employer.

What is a biomarker?

A Biomarker job involves researching and identifying biological indicators (biomarkers) that help diagnose diseases, track disease progression, or monitor treatment responses. Professionals in this field work in pharmaceuticals, biotechnology, or healthcare, using advanced laboratory techniques and data analysis to validate biomarkers for clinical use. They collaborate with scientists, clinicians, and regulatory teams to ensure biomarkers meet medical and regulatory standards. This role is crucial in developing precision medicine, improving patient care, and advancing drug development.

What skills and qualifications are needed to thrive as a biomarker?

To thrive as a biomarker scientist, you need a strong background in molecular biology, biochemistry, or related biomedical sciences, often supported by an advanced degree (MS or PhD). Familiarity with laboratory techniques such as ELISA, PCR, mass spectrometry, and data analysis software like R or SAS is essential. Critical thinking, attention to detail, and effective communication help biomarker scientists excel in both independent and collaborative research settings. These skills ensure accurate identification and validation of biomarkers, which are crucial for advancing diagnostics, drug development, and patient care.

What typical challenges do biomarker scientists face in their daily work?

Biomarker scientists often encounter challenges related to variability in biological samples, stringent validation protocols, and the complex interpretation of large or multidimensional datasets. Overcoming these obstacles requires a meticulous approach to experimental design, robust data analysis, and effective troubleshooting skills. Teamwork is also essential, as biomarker scientists regularly collaborate with clinicians, bioinformaticians, and regulatory experts to ensure research breakthroughs translate into real-world patient benefits. Developing resilience and adaptability helps professionals stay effective despite shifting project requirements or unforeseen experimental hurdles.

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Cities with the most Biomarker job openings:

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Biomarker jobs near you
Infographic showing various Biomarker job openings in the United States as of August 2026, with employment types broken down into 95% Full Time, 2% Part Time, and 3% Contract. Highlights an 81% Physical, 6% Hybrid, and 13% Remote job distribution, with an average salary of $203,468 per year, or $97.8 per hour.

Sr. Scientist, Bioanalytical Biomarker Sciences

City Therapeutics

Cambridge, MA • On-site

$38.50 - $48.25/hr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 25 days ago

Job description

TEAM: Bioanalytical and Biomarker Sciences
Position Summary:
We are seeking a highly motivated and skilled Senior Scientist with expertise in bioanalytical and biomarker assays to join our growing Translational Sciences team. This role will report to the Head of Bioanalytical and Biomarker Sciences (BBS) and will represent the BBS function across discovery and early development programs.
The successful candidate will bring strong experience in bioanalytical/biomarker assay development, qualification, validation, and will provide critical analytical support to enable data-driven decision-making from drug candidate selection through clinical development. This individual will work closely with internal research teams, cross-functional program partners, and external CROs to support both discovery- and development-stage programs.
The ideal candidate will have hands-on experience with a variety of assays including ligand binding assays, ideally, in a regulated environment. He/She will play a key role in advancing analytical method development, overseeing PK/PD sample analysis, interpreting complex data, and directing CRO activities as needed to ensure high-quality, decision-enabling bioanalytical and biomarker data.
Key Responsibilities
  • Design and execute bioanalytical and biomarker assay development, qualification, and validation activities, including, ligand-binding (ELISA, hybridization ELISA etc.), and immunogenicity assays, both internally and through CRO partners, to support drug candidate selection and regulatory submissions.
  • Generate and oversee bioanalytical data in partnership with PK scientists to support nonclinical programs and inform dose selection for Phase 1-3 clinical siRNA candidates.
  • Serve as the bioanalytical and biomarker lead on multidisciplinary project teams, collaborating with chemistry, platform biology, computational biology, clinical, regulatory, CMC, and other cross-functional partners to advance discovery and early development programs.
  • Manage CRO activities related to bioanalytical and biomarker assay development, qualification, validation, and sample analysis in support of discovery, nonclinical, and CTA/IND-enabling studies.
  • Prepare high-quality bioanalytical summaries, technical reports, and regulatory document contributions, including sections for INDs/CTAs, Investigator's Brochures, briefing books, and other submission materials.
  • Ensure compliance with applicable regulatory guidelines, SOPs, study protocols, and data integrity principles across all bioanalytical and biomarker-related activities.
  • Lead the preparation, review, and implementation of CRO Statements of Work (SOWs) for bioanalytical and biomarker activities, ensuring clear study scope, deliverables, timelines, assay requirements, sample analysis plans, reporting expectations, and executional alignment with program objectives.
  • Monitor emerging trends and best practices in bioanalytical science, biomarker assay technologies, and analytical platforms, and contribute to the implementation of innovative tools and approaches.

Qualifications
  • Ph D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 3-5+ years of relevant industry experience, or M.S. with 6+ years of relevant industry experience.
  • Strong expertise in regulated bioanalytical assay development, including assay qualification, validation, and regulatory requirements to support nonclinical and clinical studies.
  • Proficiency across multiple bioanalytical assay platforms, including ligand-binding assays, and immunogenicity assays in support of PK, PD, biomarker, and anti-drug antibody assessments.
  • Experience managing CRO relationships and externalized bioanalytical activities, including SOW preparation, review, implementation, study execution, data review, and timely delivery of high-quality reports.
  • Familiarity with regulatory expectations and guidance relevant to early-stage drug development.
  • Demonstrated adaptability, ownership, and collaborative mindset, with the ability to manage diverse responsibilities and shifting priorities in a dynamic, fast-paced environment.
  • Excellent problem-solving, analytical, and communication skills, with the ability to interpret complex quantitative data and clearly convey key findings to diverse scientific, clinical, regulatory, and cross-functional audiences.

Preferred Qualifications
  • Proven experience developing and supporting bioanalytical and biomarker assays for oligonucleotide therapeutics, with experience in siRNA or other RNA-based modalities preferred.
  • Experience working with CROs and managing outsourced bioanalytical and biomarker assay activities, including assay development, qualification, validation, sample analysis, data review, troubleshooting, and report finalization.
  • Experience supporting IND/CTA-enabling studies and/or early clinical development programs, including generation and interpretation of bioanalytical data for regulatory submissions.
  • Knowledge of regulatory bioanalytical guidance and expectations, including FDA, EMA, and ICH guidelines, is a plus.

Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including relevant skills, experience, internal equity, relevant education or training and market dynamics. In addition, this role is eligible for an annual cash bonus and equity compensation. City Therapeutics offers a comprehensive and competitive benefits package including medical, dental, vision, life insurance, health and dependent care FSA accounts, HSA/HRA accounts with company contributions, in addition to a 401(k) with competitive company match.
Per Year Salary Range: $136,000 to $154,000.
City Therapeutics is accepting resumes/CVs from direct applicants only. Recruitment agency submissions will not be accepted at this time.
City Therapeutics is an Equal Opportunity and Affirmative Action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership, or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing); or any other characteristic protected by law.
Please note this role is required to be on-site at our offices in Cambridge, MA 5 days a week.

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