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Weekend Nurse Practitioner Jobs in Raleigh, NC (NOW HIRING)

We are proud to partner with Novo Nordisk and are seeking a Full Time Nurse Practitioner, NP, to work at our Occupational Health Center located in Clayton, NC . Why You'll Love This Opportunity

Overview The PRN Nurse Practitioner will serve in a dual Hospice and Palliative Care role. In this position, they will provide comprehensive, patient-centered care across the continuum of serious ...

Overview The Per Diem Nurse Practitioner will serve in a dual Hospice and Palliative Care role. In this position, they will provide comprehensive, patient-centered care across the continuum of ...

Overview The Per Diem Nurse Practitioner will serve in a dual Hospice and Palliative Care role. In this position, they will provide comprehensive, patient-centered care across the continuum of ...

Family Nurse Practitioner (FNP)

Durham, NC · On-site

$100K - $126K/yr

Family Nurse Practitioner (FNP) Our client, a Retail Pharmacy company, is looking for a Family Nurse Practitioner (FNP) for their Durham, NC location. Responsibilities: * Client Nurse Practitioners ...

Family Nurse Practitioner (FNP)

Clayton, NC · On-site

$94K - $119K/yr

Family Nurse Practitioner (FNP) Our client, a Retail Pharmacy company, is looking for a Family Nurse Practitioner (FNP) for their Clayton, NC location. Responsibilities: * Client Nurse Practitioners ...

Family Nurse Practitioner (FNP)

Knightdale, NC · On-site

$99K - $126K/yr

Family Nurse Practitioner (Fnp) Our client, a Retail Pharmacy company, is looking for a Family Nurse Practitioner (FNP) for their Knightdale, NC location. Responsibilities: * Client Nurse ...

Nurse Practitioner

Fuquay Varina, NC · On-site

$41.85 - $90.13/hr

For Nurse Practitioners (NPs): * Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be considered * Active Family Nurse Practitioner (FNP) license in good ...

Nurse Practitioner

Fuquay Varina, NC · On-site

$41.85 - $90.13/hr

For Nurse Practitioners (NPs): * Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be considered * Active Family Nurse Practitioner (FNP) license in good ...

Nurse Practitioner

Fuquay Varina, NC · On-site

$41.85 - $90.13/hr

For Nurse Practitioners (NPs): * Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be considered * Active Family Nurse Practitioner (FNP) license in good ...

Nurse Practitioner - Advanced Practice Provider - Hospital Raleigh, NC Pay From: $48 per hour MUST: The Physician Assistant or Nurse Practitioner must have experience: Valid Nurse Practitioner or ...

We primarily work weekends, with some occasional weekdays under the Reserve Health Readiness ... Active NP license in the state * CPR/BLS Certification * Experience with Primary Care, Urgent Care ...

We primarily work weekends, with some occasional weekdays under the Reserve Health Readiness ... Active NP license in the state * CPR/BLS Certification * Experience with Primary Care, Urgent Care ...

We primarily work weekends, with some occasional weekdays under the Reserve Health Readiness ... Active NP license in the state * CPR/BLS Certification * Experience with Primary Care, Urgent Care ...

Showing results 41-60

Weekend Nurse Practitioner information

See Raleigh, NC salary details

$40.3K

$126.7K

$194.4K

How much do weekend nurse practitioner jobs pay per year?

As of Aug 17, 2026, the average yearly pay for weekend nurse practitioner in Raleigh, NC is $126,650.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,000.00 and $145,800.00 per year, depending on experience, location, and employer.

What is a weekend nurse practitioner?

Weekend Nurse Practitioners are advanced practice registered nurses (APRNs) who primarily work on weekends, providing healthcare services similar to those of physicians. They assess patients, diagnose illnesses, prescribe medications, and develop treatment plans during weekend shifts in settings like hospitals, urgent care centers, or clinics. Their role helps ensure continuous patient care outside of regular weekday hours, addressing urgent and routine health needs when other providers may be unavailable.

What does a weekend nurse practitioner do?

A weekend nurse practitioner, or weekend NP, provides healthcare services for patients during a weekend shift. Some weekend NPs only work on the weekends, while others have a varied schedule and work during the week depending on staffing needs. As a nurse practitioner, you provide primary care to patients. As part of your responsibilities, you may examine and diagnose patients, prescribe medication, and offer treatment. You may perform your duties independently or under the supervision of a physician. Weekend NP positions are available in hospitals, clinics, urgent care facilities, nursing homes, and other health care settings that operate during the weekends.

What are the key skills and qualifications needed to thrive as a weekend nurse practitioner?

To thrive as a Weekend Nurse Practitioner, you need advanced clinical skills, diagnostic abilities, and a master's or doctoral degree in nursing along with national certification and state licensure. Familiarity with electronic health records (EHRs), telehealth platforms, and point-of-care testing tools is often required. Outstanding communication, time management, and independent decision-making skills are crucial for providing care during off-hours with limited resources. These competencies ensure safe, efficient, and high-quality patient care when oversight may be reduced and urgent needs arise.

What are the typical responsibilities and work expectations for a weekend nurse practitioner?

As a Weekend Nurse Practitioner, you are often responsible for providing primary or urgent care services during weekends, which may include assessing patients, diagnosing conditions, prescribing medications, and coordinating care with physicians and other healthcare staff. You may also handle walk-in patients, manage acute cases, and ensure continuity of care for patients admitted over the weekend. The role often requires autonomy, adaptability, and strong decision-making skills, as weekend coverage may involve fewer on-site resources and increased reliance on your clinical judgment. Collaboration with nurses, support staff, and on-call physicians is common, and effective teamwork is essential for delivering quality patient care in this setting.

What is the difference between Weekend Nurse Practitioner vs Weekend Physician Assistant?

AspectWeekend Nurse PractitionerWeekend Physician Assistant
CredentialsMaster's or Doctoral degree in Nursing, Nurse Practitioner certificationMaster's degree in Physician Assistant Studies, PA certification
Work EnvironmentClinics, urgent care, primary care settings, often in outpatient facilitiesUrgent care, emergency departments, outpatient clinics, similar settings
Employer & IndustryHospitals, clinics, healthcare organizations, outpatient facilitiesHospitals, urgent care centers, clinics, healthcare organizations

Weekend Nurse Practitioners and Weekend Physician Assistants share similar work environments and employer types, often working in outpatient and urgent care settings. The main difference lies in their credentials and certification pathways, with NPs holding advanced nursing degrees and PAs completing physician assistant programs. Both roles are vital for providing healthcare services during weekends, offering flexibility and extended care hours.

What are the most commonly searched types of Nurse Practitioner jobs in Raleigh, NC?

The most popular types of Nurse Practitioner jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Weekend Nurse Practitioner jobs?

Cities near Raleigh, NC with the most Weekend Nurse Practitioner job openings:

Infographic showing various Weekend Nurse Practitioner job openings in Raleigh, NC as of August 2026, with employment types broken down into 3% As Needed, 69% Full Time, 20% Part Time, and 8% Contract. Highlights an 92% In-person, and 8% Remote job distribution, with an average salary of $126,650 per year, or $60.9 per hour.

Nurse Practitioner, NP

Premise Health

Clayton, NC • On-site

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 15 days ago


Premise Health rating

8.0

Company rating: 8.0 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

87th of 887 rated healthcare providers


Job description

Premise's mission is to help people get, stay, and be well. We hope you will join us in our mission and experience why amazing health starts with amazing healthcare. For more information, visit www.jobs.premisehealth.com.  We are proud to partner with Novo Nordiskand are seeking a Full Time Nurse Practitioner, NP, to work at our Occupational Health Center located in Clayton, NC. Why You'll Love This Opportunity
  • Autonomous Practice: Enjoy the independence of serving as the sole provider in the health center while receiving collaborative support from nearby clinical teams when needed.
  • Predictable Schedule:
    • Monday, Tuesday, Wednesday & Friday: 8:00 AM – 5:00 PM
    • Thursday: 12:00 PM – 9:00 PM
  • Ideal Patient Volume: Focus on delivering quality care without the pressure of high patient volumes.
  • Supportive Environment: Practice independently while knowing an experienced team is available for collaboration and support.
  • Outstanding Benefits: Competitive benefits package, generous paid time off, and a CME allowance to support your continued professional growth.

What You’ll Do

  • Conducts physical exams and preventive health measures per guidelines
  • Performs procedures such as injections, suturing, wound care, and infection management
  • Develops patient care plans, records progress, and ensures continuity of care
  • Educates patients on treatment plans, health maintenance, and development
  • Orders and interprets diagnostic tests to assess clinical conditions
  • Collaborates with physicians and healthcare teams for comprehensive care
  • Prescribes or recommends treatments, including medications and therapies
  • Refers patients to specialists or physicians as needed
  • Maintains patient health records ensure accurate and up-to-date documentation and records
  • Educates and coaches nursing staff on best practices
  • Performs other duties as assigned

What You’ll Bring

  • Maintains state RN licenses/certificates to practice
  • Maintains Nurse Practitioner licenses/certificates to practice
  • Maintains State Prescriptive Authority (if applicable)
  • Federal DEA license (matching each state of practice as applicable)
  • Current national certification (ANCC or AANP required)
  • Master’s Degree in Science of Nursing (if Master Degree in Science certificate does not state Nursing on it then a copy of transcripts is required)
  • Current certification with hands-on training in AHA, ARC or equivalent Basic Life Support for health care providers is required; Advanced Cardiac Life Support may also be required based on contract scope of services
  • At least three years of clinical experience as a Nurse Practitioner in an ambulatory care, occupational health, family practice or emergency department setting

Work-life balance is at the foundation of how decisions are made and where Premise is headed. We can only help people get, stay, and be well if we do the same for ourselves. In addition to competitive pay, Premise offers full-time team members benefits including medical, dental, vision, life and disability insurance, a 401(k) program with company match, paid holidays and vacation time, a company-sponsored wellness program, EAP, access to virtual primary care and virtual behavioral health at no cost for team members and their dependents. Additional benefits can be viewed here: https://jobs.premisehealth.com/benefits.

Premise is an equal opportunity employer; we value inclusion and do not discriminate based on race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy and related conditions), gender identity or expression, sexual orientation, age, physical or mental disability, genetic information, past, current or prospective service in the uniformed services, or any other characteristic protected under applicable federal, state, or local law.

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About Premise Health

Sourced by ZipRecruiter

Premise Health is the world's leading direct healthcare provider and one of the largest digital providers in the country, serving over 11 million eligible lives across more than 2,500 of the largest commercial and municipal employers in the U.S. Premise partners with its clients to offer fully connected care - in-person and in the digital environment. It operates more than 800 onsite and nearsite wellness centers in 45 states and Guam, delivering care through the Digital Wellness Center and onsite, nearsite, mobile, and event solutions. Premise delivers value by simplifying complexity and breaking down barriers to give diverse member populations access to convenient, integrated, high-quality care. We offer more than 30 products, delivering the breadth and depth of care required to serve organizations' total populations. The result is healthcare that meets the needs of members and their families, helping them live healthier while lowering costs for organizations.

Industry

Health care and social assistance

Company size

5,001 - 10,000 Employees

Headquarters location

Brentwood, TN, US

Year founded

1975