1

Weekend Nurse Practitioner Jobs in Raleigh, NC (NOW HIRING)

Nurse Practitioner

Clayton, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Knightdale, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend. Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Raleigh, NC ยท On-site

$41.85 - $90.13/hr

FT Weekend Leesville Church Rd/surrounding Raleigh areas float. FTW is 30-35hrs/week including ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Knightdale, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend. Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Raleigh, NC ยท On-site

$41.85 - $90.13/hr

FT Weekend Leesville Church Rd/surrounding Raleigh areas float. FTW is 30-35hrs/week including ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Raleigh, NC ยท On-site

$41.85 - $90.13/hr

FT Weekend Leesville Church Rd/surrounding Raleigh areas float. FTW is 30-35hrs/week including ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Knightdale, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend. Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Clayton, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Clayton, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Raleigh, NC ยท On-site

$41.85 - $90.13/hr

FT Weekend Leesville Church Rd/surrounding Raleigh areas float. FTW is 30-35hrs/week including ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Knightdale, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend. Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Nurse Practitioner

Clayton, NC ยท On-site

$41.85 - $90.13/hr

FT is 30-35hrs/week including every other weekend Position Summary: As the largest retail health ... Minimum one year of NP experience is preferred; however, qualified new graduate NPs will be ...

Physician Assistant / PA - Cardiology

Cary, NC ยท On-site

$125K - $140K/yr

No call, no weekends * Outpatient setting * NP will see on average 18-22 patients per day - this will be a mix of new and established patients * APP will just a team with 1 MD, 2 APPs - total team ...

next page

Showing results 1-20

Weekend Nurse Practitioner information

See Raleigh, NC salary details

$40.3K

$126.7K

$194.4K

How much do weekend nurse practitioner jobs pay per year?

As of Sep 8, 2026, the average yearly pay for weekend nurse practitioner in Raleigh, NC is $126,650.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,000.00 and $145,800.00 per year, depending on experience, location, and employer.

What is a weekend nurse practitioner?

Weekend Nurse Practitioners are advanced practice registered nurses (APRNs) who primarily work on weekends, providing healthcare services similar to those of physicians. They assess patients, diagnose illnesses, prescribe medications, and develop treatment plans during weekend shifts in settings like hospitals, urgent care centers, or clinics. Their role helps ensure continuous patient care outside of regular weekday hours, addressing urgent and routine health needs when other providers may be unavailable.

What does a weekend nurse practitioner do?

A weekend nurse practitioner, or weekend NP, provides healthcare services for patients during a weekend shift. Some weekend NPs only work on the weekends, while others have a varied schedule and work during the week depending on staffing needs. As a nurse practitioner, you provide primary care to patients. As part of your responsibilities, you may examine and diagnose patients, prescribe medication, and offer treatment. You may perform your duties independently or under the supervision of a physician. Weekend NP positions are available in hospitals, clinics, urgent care facilities, nursing homes, and other health care settings that operate during the weekends.

What are the key skills and qualifications needed to thrive as a weekend nurse practitioner?

To thrive as a Weekend Nurse Practitioner, you need advanced clinical skills, diagnostic abilities, and a master's or doctoral degree in nursing along with national certification and state licensure. Familiarity with electronic health records (EHRs), telehealth platforms, and point-of-care testing tools is often required. Outstanding communication, time management, and independent decision-making skills are crucial for providing care during off-hours with limited resources. These competencies ensure safe, efficient, and high-quality patient care when oversight may be reduced and urgent needs arise.

What are the typical responsibilities and work expectations for a weekend nurse practitioner?

As a Weekend Nurse Practitioner, you are often responsible for providing primary or urgent care services during weekends, which may include assessing patients, diagnosing conditions, prescribing medications, and coordinating care with physicians and other healthcare staff. You may also handle walk-in patients, manage acute cases, and ensure continuity of care for patients admitted over the weekend. The role often requires autonomy, adaptability, and strong decision-making skills, as weekend coverage may involve fewer on-site resources and increased reliance on your clinical judgment. Collaboration with nurses, support staff, and on-call physicians is common, and effective teamwork is essential for delivering quality patient care in this setting.

What is the difference between Weekend Nurse Practitioner vs Weekend Physician Assistant?

AspectWeekend Nurse PractitionerWeekend Physician Assistant
CredentialsMaster's or Doctoral degree in Nursing, Nurse Practitioner certificationMaster's degree in Physician Assistant Studies, PA certification
Work EnvironmentClinics, urgent care, primary care settings, often in outpatient facilitiesUrgent care, emergency departments, outpatient clinics, similar settings
Employer & IndustryHospitals, clinics, healthcare organizations, outpatient facilitiesHospitals, urgent care centers, clinics, healthcare organizations

Weekend Nurse Practitioners and Weekend Physician Assistants share similar work environments and employer types, often working in outpatient and urgent care settings. The main difference lies in their credentials and certification pathways, with NPs holding advanced nursing degrees and PAs completing physician assistant programs. Both roles are vital for providing healthcare services during weekends, offering flexibility and extended care hours.

Can a weekend nurse practitioner work 3 days a week?

A weekend nurse practitioner can work three days a week if the employer's schedule and state regulations permit it. Many nurse practitioners have flexible schedules, but they must meet licensing, credentialing, and practice scope requirements, which can vary by location and employer policies.

What is a good side hustle for a weekend nurse practitioner?

A weekend nurse practitioner can pursue telehealth consulting, providing virtual patient care or health advice outside regular hours. They can also offer health coaching, wellness assessments, or freelance medical writing, leveraging their clinical skills and certifications to generate additional income on weekends.

What are the most commonly searched types of Nurse Practitioner jobs in Raleigh, NC?

The most popular types of Nurse Practitioner jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Weekend Nurse Practitioner jobs?

Cities near Raleigh, NC with the most Weekend Nurse Practitioner job openings:

Infographic showing various Weekend Nurse Practitioner job openings in Raleigh, NC as of August 2026, with employment types broken down into 3% As Needed, 63% Full Time, 15% Part Time, and 19% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $126,650 per year, or $60.9 per hour.

Nurse Practitioner (NP)

Amergis Healthcare Staffing

Holly Springs, NC โ€ข On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 4 days ago


Job description

The Nurse Practitioner provides health care services to patients within scope of license, performs physical examinations and diagnostic tests, assessments and screenings, prescribes medications, and instructs patients and family members on medical conditions and treatment.  Additionally, the Nurse Practitioner may have an area of specialty practice.

Minimum Requirements:

  • Current Nurse Practitioner Certification and license in the state of practice required
  • Certification as a Nurse Practitioner by a nationally accredited nursing organization (e.g. American Academy of Nurse Practitioners โ€“ AANP, American Nurses Credentialing Center โ€“ ANCC) is preferred
  • Specialty Certification as per client request and or state regulations if applicable 
  • One year experience as an NP preferred
  • Maintain collaboration agreements, per state requirements
  • Current CPR if applicable
  • TB questionnaire, PPD or chest x-ray if applicable 
  • Current Health certificate (per contract or state regulation) 
  • Must meet all federal, state and local requirements 
  • Must be at least 18 years of age 
Benefits
At Amergis, we firmly believe that our employees are the heartbeat of our organization and we are happy to offer the following benefits:
  • Competitive pay & weekly paychecks
  • Health, dental, vision, and life insurance
  • 401(k) savings plan
  • Awards and recognition programs 
*Benefit eligibility is dependent on employment status. 

About Amergis
Amergis, formerly known as Maxim Healthcare Staffing, has served our clients and communities by connecting people to the work that matters since 1988. We provide meaningful opportunities to our extensive network of healthcare and school-based professionals, ready to work in any hospital, government facility, or school. Through partnership and innovation, Amergis creates unmatched staffing experiences to deliver the best workforce solutions.  

Amergis is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.