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Weekend Nurse Practitioner Jobs in Raleigh, NC (NOW HIRING)

Accounting Search

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

USA Staffing Network

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Client Growth Resources

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

RRC Solutions Group

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Soap Creek Resources

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

ExcelliSearch, Inc.

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Experienced Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

SteveRecruiter, LLC

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Your Talent Team LLC

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Ron Sunshine Associates LLC

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Zaddy Solutions

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

MJR Recruiting

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Welsh and Associates

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Experienced Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Pernini Legal

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Riverscape Search Agency

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

Ridgemont Resources

Nurse Practitioner

Cary, NC · On-site

$125K/yr

Nurse Practitioner Opportunity Well-established outpatient rheumatology practice is seeking an ... No weekends Compensation & Benefits * Salary starting at $125k and up * Medical insurance paid by ...

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All JobsNurse Practitioner JobsWeekend Nurse Practitioner JobsWeekend Nurse Practitioner Jobs in Raleigh, NC

Weekend Nurse Practitioner information

See Raleigh, NC salary details

$40.3K

$126.7K

$194.4K

How much do weekend nurse practitioner jobs pay per year?

As of Sep 8, 2026, the average yearly pay for weekend nurse practitioner in Raleigh, NC is $126,650.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,000.00 and $145,800.00 per year, depending on experience, location, and employer.

What is a weekend nurse practitioner?

Weekend Nurse Practitioners are advanced practice registered nurses (APRNs) who primarily work on weekends, providing healthcare services similar to those of physicians. They assess patients, diagnose illnesses, prescribe medications, and develop treatment plans during weekend shifts in settings like hospitals, urgent care centers, or clinics. Their role helps ensure continuous patient care outside of regular weekday hours, addressing urgent and routine health needs when other providers may be unavailable.

What does a weekend nurse practitioner do?

A weekend nurse practitioner, or weekend NP, provides healthcare services for patients during a weekend shift. Some weekend NPs only work on the weekends, while others have a varied schedule and work during the week depending on staffing needs. As a nurse practitioner, you provide primary care to patients. As part of your responsibilities, you may examine and diagnose patients, prescribe medication, and offer treatment. You may perform your duties independently or under the supervision of a physician. Weekend NP positions are available in hospitals, clinics, urgent care facilities, nursing homes, and other health care settings that operate during the weekends.

What are the key skills and qualifications needed to thrive as a weekend nurse practitioner?

To thrive as a Weekend Nurse Practitioner, you need advanced clinical skills, diagnostic abilities, and a master's or doctoral degree in nursing along with national certification and state licensure. Familiarity with electronic health records (EHRs), telehealth platforms, and point-of-care testing tools is often required. Outstanding communication, time management, and independent decision-making skills are crucial for providing care during off-hours with limited resources. These competencies ensure safe, efficient, and high-quality patient care when oversight may be reduced and urgent needs arise.

What are the typical responsibilities and work expectations for a weekend nurse practitioner?

As a Weekend Nurse Practitioner, you are often responsible for providing primary or urgent care services during weekends, which may include assessing patients, diagnosing conditions, prescribing medications, and coordinating care with physicians and other healthcare staff. You may also handle walk-in patients, manage acute cases, and ensure continuity of care for patients admitted over the weekend. The role often requires autonomy, adaptability, and strong decision-making skills, as weekend coverage may involve fewer on-site resources and increased reliance on your clinical judgment. Collaboration with nurses, support staff, and on-call physicians is common, and effective teamwork is essential for delivering quality patient care in this setting.

What is the difference between Weekend Nurse Practitioner vs Weekend Physician Assistant?

AspectWeekend Nurse PractitionerWeekend Physician Assistant
CredentialsMaster's or Doctoral degree in Nursing, Nurse Practitioner certificationMaster's degree in Physician Assistant Studies, PA certification
Work EnvironmentClinics, urgent care, primary care settings, often in outpatient facilitiesUrgent care, emergency departments, outpatient clinics, similar settings
Employer & IndustryHospitals, clinics, healthcare organizations, outpatient facilitiesHospitals, urgent care centers, clinics, healthcare organizations

Weekend Nurse Practitioners and Weekend Physician Assistants share similar work environments and employer types, often working in outpatient and urgent care settings. The main difference lies in their credentials and certification pathways, with NPs holding advanced nursing degrees and PAs completing physician assistant programs. Both roles are vital for providing healthcare services during weekends, offering flexibility and extended care hours.

Can a weekend nurse practitioner work 3 days a week?

A weekend nurse practitioner can work three days a week if the employer's schedule and state regulations permit it. Many nurse practitioners have flexible schedules, but they must meet licensing, credentialing, and practice scope requirements, which can vary by location and employer policies.

What is a good side hustle for a weekend nurse practitioner?

A weekend nurse practitioner can pursue telehealth consulting, providing virtual patient care or health advice outside regular hours. They can also offer health coaching, wellness assessments, or freelance medical writing, leveraging their clinical skills and certifications to generate additional income on weekends.
More about Weekend Nurse Practitioner jobs

What are the most commonly searched types of Nurse Practitioner jobs in Raleigh, NC?

The most popular types of Nurse Practitioner jobs in Raleigh, NC are:

What are popular job titles related to Weekend Nurse Practitioner jobs in Raleigh, NC?

For Weekend Nurse Practitioner jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Weekend Nurse Practitioner jobs in Raleigh, NC look for?

The top searched job categories for Weekend Nurse Practitioner jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Weekend Nurse Practitioner jobs?

Cities near Raleigh, NC with the most Weekend Nurse Practitioner job openings:

Weekend Nurse Practitioner jobs near you
Infographic showing various Weekend Nurse Practitioner job openings in Raleigh, NC as of August 2026, with employment types broken down into 3% As Needed, 63% Full Time, 15% Part Time, and 19% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $126,650 per year, or $60.9 per hour.

Nurse Practitioner

Accounting Search

Cary, NC • On-site

$125K/yr

Other

Medical, Vision, Retirement, PTO

Re-posted 6 days ago

Job description

Nurse Practitioner Opportunity

Well-established outpatient rheumatology practice is seeking an experienced Nurse Practitioner to join our team. We are open to NPs with backgrounds in Primary Care, Internal Medicine, or Rheumatology.

This position offers an excellent schedule, employer-paid benefits, and the opportunity to transition into or continue a career in rheumatology.

Schedule
  • 4 days per week in the clinic
  • Half-day Friday remote
  • 8:30 AM–5:00 PM
  • No call
  • No weekends
Compensation & Benefits
  • Salary starting at $125k and up
  • Medical insurance paid by the practice
  • Vision insurance paid by the practice
  • 3 weeks PTO
  • 8 paid federal holidays
  • 401(k) with 4% employer match
  • $2,500 CME allowance
  • 3 paid CME days
  • Paid malpractice insurance
  • 6 weeks paid maternity leave
Qualifications
  • Licensed and Board-Certified Nurse Practitioner
  • DEA license or ability to obtain
  • 3+ years of experience in Primary Care, Internal Medicine, or Rheumatology preferred
  • Strong clinical and patient communication skills

Apply