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Upstream Fermentation Manager Jobs (NOW HIRING)

Fermentation Manager

Akron, OH

$17.25 - $20/hr

BioVerde Tech, LLC is seeking a talented and motivated Fermentation Manager to lead methanotroph ... Successfully lead the process development, scale-up and upstream production of engineered ...

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... managing key aspects of the fermentation process. This includes preparing cultures and inoculums ... control of upstream fermentation vessels. 8. The planning, organization, and sharing of the ...

Pilot Fermentation Engineer - Decatur, IL The Pilot Fermentation Engineer is responsible for ... managers, engineering, operations, and R&D staff (upstream process development, analytical ...

... upstream processand tech transfer effort. Job Responsibilities: * Design, set-up,and executelab-scale fermentation experimentstovalidateprocess parameters. * Support the Technical Manager in ...

Senior Proccess Engineer

Omaha, NE · On-site

$99K - $128K/yr

... managing technical collaborations with external engineering partners and CROs to drive the ... Collaborate closely with R&D (strain design and fermentation) to integrate upstream, downstream ...

Senior Proccess Engineer

Omaha, NE

$99K - $128K/yr

... managing technical collaborations with external engineering partners and CROs to drive the ... Collaborate closely with R&D (strain design and fermentation) to integrate upstream, downstream ...

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Upstream Fermentation Manager information

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$24.5K

$59.5K

$116K

How much do upstream fermentation manager jobs pay per year?

As of Jun 13, 2026, the average yearly pay for upstream fermentation manager in the United States is $59,525.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,000.00 and $68,500.00 per year, depending on experience, location, and employer.

What is the difference between Upstream Fermentation Manager vs Fermentation Supervisor?

AspectUpstream Fermentation ManagerFermentation Supervisor
ResponsibilitiesOversees entire fermentation process, manages teams, develops protocolsSupervises daily fermentation operations, monitors equipment and quality
CredentialsBachelor's degree in microbiology, biochemistry, or related field; experience in fermentationAssociate's or bachelor's degree; hands-on fermentation experience
Work EnvironmentLaboratory and production facilities, managerial settingProduction floor, laboratory, and shift-based work
Industry UsageCommon in biotech, pharmaceuticals, and large-scale fermentation facilitiesTypically found in manufacturing plants and smaller fermentation operations

The Upstream Fermentation Manager generally has broader responsibilities, including team management and protocol development, while the Fermentation Supervisor focuses on daily operational oversight. Both roles require fermentation knowledge, but the manager position often demands more experience and leadership skills.

What are the key skills and qualifications needed to thrive as an Upstream Fermentation Manager, and why are they important?

To thrive as an Upstream Fermentation Manager, you need a strong background in microbiology, biochemical engineering, or a related field, often supported by a relevant advanced degree and experience in fermentation processes. Familiarity with bioreactors, process control systems, and data analysis software, as well as certifications in Good Manufacturing Practice (GMP), are typically required. Leadership, problem-solving, and effective communication are critical soft skills for managing teams and troubleshooting process issues. These skills and qualifications are vital to ensure efficient, high-yield fermentation operations and regulatory compliance in biopharmaceutical or industrial biotechnology environments.

What does an Upstream Fermentation Manager do?

An Upstream Fermentation Manager oversees the initial stages of bioprocessing, focusing on the cultivation of microorganisms or cells to produce desired products such as pharmaceuticals, enzymes, or biofuels. They are responsible for managing fermentation operations, optimizing growth conditions, ensuring quality control, and supervising a team of technicians or scientists. This role involves troubleshooting process issues, maintaining compliance with regulatory standards, and collaborating with other departments to achieve production goals.

What are some common challenges faced by an Upstream Fermentation Manager and how can they be addressed?

Upstream Fermentation Managers often face challenges such as optimizing fermentation conditions to maximize yield, ensuring consistent batch-to-batch performance, and troubleshooting equipment malfunctions or contamination issues. Effective collaboration with process engineers, quality assurance teams, and downstream processing groups is crucial to quickly resolve issues and maintain production targets. Staying current with advancements in fermentation technology and implementing robust standard operating procedures can help address these challenges and improve overall process efficiency.

$17.25 - $20/hr

Other

Posted 16 days ago


Job description

BioVerde Tech, LLC is seeking a talented and motivated Fermentation Manager to lead methanotroph fermentation research, development and scaleup activities at its Ohio laboratory and pilot site on the campus of the University of Akron. Thorough hands-on understanding of fermentation technology is required along with experience in process design and optimization, technical transfer, control system implementation, analytical process monitoring, and scaleup from bench to pilot.


The successful candidate will have a current operational knowledge of high cell-density industrial fermentation platforms and methodologies, including fed-batch and continuous processes and harvest operations. Experience in gas fermentation is desirable. This role offers the opportunity to contribute to groundbreaking advancements in biotechnology while working with a passionate and innovative team committed to a sustainable future.


*Direct applicants only.


About BioVerde: BioVerde Tech, LLC is pioneering the commercialization of low-carbon-intensity chemical and fuel products from renewable feedstock sources using engineered methanotrophic microbes. By replacing petroleum-based inputs the BioVerde technology platform offers a sustainable and cost-effective alternative for industrial applications. BioVerde was recently awarded over $12M in Federal grant funding from the US Department of Commerce’s Economic Development Administration Technology Hubs initiative for scaleup of its patent-protected technologies.


Essential Duties and Responsibilities:

  • Successfully lead the process development, scale-up and upstream production of engineered methanotrophic bacteria for biomass and chemical products derived from aerobic methane fermentation
  • Bioreactor / gas feed setup, operation and proper handling of samples (gas, liquid, cell mass) and harvested biomass and broth at benchtop and pilot scales
  • Develop and maintain SOPs internally and in partnership with technology providers / vendors
  • Continuous improvement of technical capabilities and quality practices
  • Broad use of expertise and knowledge to solve complex non-routine technical problems
  • Evaluate process data, perform troubleshooting and root-cause analysis, and provide strategic recommendations leading to improved economics and process robustness
  • Lead the execution, completion and review of manufacturing documentation including batch production records, quality system documents and reports
  • Maintain detailed records of experimental procedures, data, and results using ELN and LIMS;
  • Prepare reports and presentations for internal and external stakeholders
  • Serve as subject matter expert within the company and with partners/customers
  • Ensure compliance with all environmental, health, and safety regulations, policies and procedures
  • Supervise, mentor and provide training for development of fermentation staff as company grows
  • Contribute to building a highly collaborative culture that encourages continuous learning, improvement, and innovation, and encourages and mentors team members to expand their technical skill base


Required Skills and Qualifications:

Education and Experience:

  • BS (+10 y), MS(+5 y) or PhD degree in Life Sciences, Chemistry, Chemical/Biochemical Engineering or related discipline is required. A PhD is preferred but not essential depending upon relevant experience
  • Minimum 5 – 10 years of fermentation experience in an industrial setting. PhD with post doctorate work experience in fermentation would be considered.


Technical Skills and Experience:

  • Operational experience in high cell density fermentation
  • Operational experience with scale-up of fermentation processes from bench (1 L) to pilot (100 L+)
  • Operational experience with biomass and liquid harvest processes including tangential flow filtration, depth filtration and centrifugation
  • Experience with gas fermentation and safety systems desirable


Soft Skills:

  • Strong organizational, interpersonal and project management skills
  • Proven track record of effective performance and management potential
  • Highly independent and self-motivated; must work well as part of a team that includes local and remote members
  • Ability to work in a fast-paced, innovative environment and adapt to evolving priorities
  • Excellent written and verbal communication skills


Work Environment

The position is full-time in Akron, Ohio (University of Akron National Polymer Innovation Center).


Equal Opportunity Statement

BioVerde Tech LLC is an Equal Opportunity Employer. We are committed to fostering an inclusive and diverse workplace where all individuals are treated with respect and dignity. We welcome applications from candidates of all backgrounds and do not discriminate based on race, color, religion, sex, sexual orientation, gender, identity, national origin, age, disability, veteran status or any other legally protected status. If hired, BioVerde Tech LLC will require that you provide evidence of your legal right to work in the United States. BioVerde will not sponsor applicants for work visas at any time during recruitment or employment.