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Trial Master File Jobs in Raleigh, NC (NOW HIRING)

Winaxis

Clinical Research Coordinator

Raleigh, NC · On-site

$23.50 - $31.25/hr

Maintain Trial Master File (TMF), Investigator Site File (ISF), and essential study documents. Report adverse events and serious adverse events according to protocol and regulatory requirements.

AstraZeneca

Global Study Manager

Durham, NC

Trial Master File (TMF) Management * Risk Management * Budget Tracking and Reconciliation * Cross-Functional Collaboration * Project Management * Stakeholder Management Why AstraZeneca: Here, your ...

New

AstraZeneca

Global Study Manager

Durham, NC · On-site

Trial Master File (TMF) Management * Risk Management * Budget Tracking and Reconciliation * Cross-Functional Collaboration * Project Management * Stakeholder Management Why AstraZeneca: Here, your ...

AstraZeneca

Global Study Manager

Durham, NC · On-site

Trial Master File (TMF) Management * Risk Management * Budget Tracking and Reconciliation * Cross-Functional Collaboration * Project Management * Stakeholder Management Why AstraZeneca: Here, your ...

AstraZeneca

Global Study Manager

Durham, NC

Ensure study-related documentation within assigned scope is complete, accurate, and maintained in the Trial Master File (TMF). Support budget management activities, including invoice reconciliation ...

New

Aerogen

Clinical Trial Manager

Morrisville, NC · On-site

Contribute high‑quality required documents for inclusion in the Trial Master File to ensure inspection readiness. * Assist in developing study documents and tools, including informed consent forms ...

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

... in the Trial Master File to ensure inspection readiness. • Assist in the development of study documents and tools including informed consent forms, project plans, budgets, logs, templates ...

Veranex

Sr Clinical Research Associate

Raleigh, NC · On-site

$98K - $140K/yr

Supports and maintains documentation of all clinical research activities in the study trial master file (TMF), e.g., monitoring reports, site correspondence, device inventory information. * Drives ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

TalentBurst, Inc.

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. " Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

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All JobsTrial Master File JobsTrial Master File Jobs in Raleigh, NC

Trial Master File information

See Raleigh, NC salary details

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$38

$75

How much do trial master file jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for trial master file in Raleigh, NC is $38.39, according to ZipRecruiter salary data. Most workers in this role earn between $24.86 and $46.70 per hour, depending on experience, location, and employer.

What is a trial master file?

A Trial Master File (TMF) job involves managing and maintaining essential documents related to clinical trials to ensure compliance with regulatory requirements. Professionals in this role organize, track, and audit critical trial documentation to support inspections and submissions. They work closely with clinical teams, sponsors, and regulatory authorities to ensure proper documentation is accurate, complete, and audit-ready throughout the trial lifecycle.

What are the typical responsibilities and daily tasks of a trial master file specialist?

As a TMF Specialist, your main responsibilities include managing, organizing, and maintaining all essential clinical trial documentation to ensure compliance with regulatory standards. On a daily basis, you will review and upload documents to eTMF systems, track document status, resolve discrepancies, and support study teams during audits or inspections. You'll collaborate closely with clinical research associates, project managers, and quality assurance teams to ensure the TMF is complete and inspection-ready at all times. The work is detail-oriented and deadline-driven, offering opportunities to develop expertise in regulatory standards and advance into roles such as TMF Manager or Clinical Trial Associate.

What are the key skills and qualifications needed to thrive in the trial master file position, and why are they important?

To thrive in a Trial Master File (TMF) Specialist role, you need meticulous organizational skills, comprehensive knowledge of regulatory requirements for clinical trials, and often a bachelor's degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, document management platforms, and relevant GCP (Good Clinical Practice) certifications is commonly required. Attention to detail, proactive communication, and the ability to collaborate effectively across clinical research teams are key soft skills. These competencies ensure regulatory compliance and seamless documentation, which are critical for the successful conduct and audit-readiness of clinical trials.

What are popular job titles related to Trial Master File jobs in Raleigh, NC?

For Trial Master File jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Trial Master File jobs in Raleigh, NC look for?

The top searched job categories for Trial Master File jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Trial Master File jobs?

Cities near Raleigh, NC with the most Trial Master File job openings:

Trial Master File jobs near you
Infographic showing various Trial Master File job openings in Raleigh, NC as of September 2026, with employment types broken down into 71% Full Time, 10% Temporary, and 19% Contract. Highlights an 82% In-person, and 18% Remote job distribution, with an average salary of $79,855 per year, or $38.4 per hour.

Clinical Research Coordinator

Raleigh, NC • On-site

Winaxis
IT Services • 11 - 50 employees
Learn more about Winaxisexternal

$23.50 - $31.25/hr

Full-time

Medical, PTO

Posted 5 days ago

Job description

Job Title : Clinical Research Coordinator (CRC) Experience : 0–3 Years Location : Dallas, Texas Employment Type : Full-time Job Summary:- We are looking for a motivated and detail-oriented Clinical Research Coordinator to support the planning, execution, and management of clinical research studies. The ideal candidate should have 0–3 years of experience in clinical research and a strong understanding of Good Clinical Practice (GCP), ICH guidelines, and regulatory requirements. Fresh graduates with relevant internships or clinical research training are encouraged to apply. Key Responsibilities Coordinate and manage clinical research studies in compliance with study protocols, ICH-GCP guidelines, and applicable regulations. Screen, recruit, and enroll study participants. Obtain informed consent from study participants. Schedule and coordinate patient visits and follow-up appointments. Collect, verify, and maintain accurate study documentation and source data. Enter clinical data into Electronic Data Capture (EDC) systems. Maintain Trial Master File (TMF), Investigator Site File (ISF), and essential study documents. Report adverse events and serious adverse events according to protocol and regulatory requirements. Coordinate with investigators, sponsors, CROs, and ethics committees. Prepare for monitoring visits, audits, and regulatory inspections. Ensure protocol compliance and participant safety throughout the study. Assist with study start-up, close-out activities, and regulatory submissions. Required Qualifications Bachelor's or Master's degree in Life Sciences, Pharmacy, Nursing, Biotechnology, Microbiology, or a related field. 0–3 years of experience in clinical research or clinical trial coordination. Knowledge of ICH-GCP, FDA, and local regulatory guidelines. Familiarity with EDC systems and Microsoft Office. Strong organizational, communication, and documentation skills. Ability to work independently and as part of a multidisciplinary team. Preferred Qualifications GCP Certification. Clinical Research certification is an added advantage. Experience with site coordination or patient recruitment. Knowledge of clinical trial documentation and regulatory submissions. Key Skills Clinical Trial Coordination ICH-GCP Compliance Patient Recruitment Informed Consent Process Source Documentation Electronic Data Capture (EDC) Trial Master File (TMF) Regulatory Documentation Adverse Event Reporting Data Management Communication & Coordination Attention to Detail Time Management Benefits Competitive salary Health insurance Performance-based incentives Training and career development opportunities Paid leave and holidays Exposure to global clinical research projects How to Apply Interested candidates can submit their updated resume along with a cover letter highlighting their clinical research experience, certifications, and relevant skills.