ZipRecruiter

Log In

1

Trial Master File Jobs in Raleigh, NC (NOW HIRING)

IQVIA

Clinical Trial Assistant

Durham, NC · On-site

$34K - $118K/yr

Essential Functions Assist Clinical Research Associates (CRAs) and Regulatory and Start-Up (RSU) team with accurately updating and maintaining clinical documents and systems (e.g., Trial Master File ...

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

... in the Trial Master File to ensure inspection readiness. • Assist in the development of study documents and tools including informed consent forms, project plans, budgets, logs, templates ...

Fortrea

Clinical Trials Associate I

Durham, NC · On-site

$30.25 - $41.50/hr

Maintain Trial Master File documentation within the appropriate TMF platform, participate in TMF QC, as assigned, and track and /archive as applicable. * Audit and CAPA tracking. * Set up and ...

Fortrea

Clinical Trials Associate I

Durham, NC · On-site

$32.25 - $44.25/hr

Maintain Trial Master File documentation within the appropriate TMF platform, participate in TMF QC, as assigned, and track and /archive as applicable. * Audit and CAPA tracking. * Set up and ...

IQVIA, Inc.

CRA 2, Oncology, IQVIA

Durham, NC · On-site

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

CRA 2, Oncology, IQVIA

Durham, NC · On-site

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

CRA 2, Oncology, IQVIA

Durham, NC · On-site

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

Syneos Health

CTM - Future Roles (US)

Morrisville, NC · On-site

Reconciles contents of the ISF with the Trial Master File (TMF). Ensures the investigator/physician site is aware of the requirement of archiving essential documents in accordance with local ...

IQVIA, Inc.

Sr. CRA 1, Oncology, IQVIA Biotech

Durham, NC · On-site

$87K - $169K/yr

May support start-up phase. • Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is ...

IQVIA

Clinical Research Associate, Full Service

Durham, NC · On-site

$47K - $169K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) verify that the Investigator's Site File (ISF) is maintained in accordance with GCP / ICH ...

IQVIA

Clinical Research Associate

Durham, NC · On-site

$87K - $182K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

Clinical Research Associate

Durham, NC · On-site

$71K - $189K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

next page

Showing results 1-20

All JobsTrial Master File JobsTrial Master File Jobs in Raleigh, NC

Trial Master File information

See Raleigh, NC salary details

$11

$38

$75

How much do trial master file jobs pay per hour?

As of Jun 23, 2026, the average hourly pay for trial master file in Raleigh, NC is $38.39, according to ZipRecruiter salary data. Most workers in this role earn between $24.86 and $46.70 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Trial Master File position, and why are they important?

To thrive in a Trial Master File (TMF) Specialist role, you need meticulous organizational skills, comprehensive knowledge of regulatory requirements for clinical trials, and often a bachelor's degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, document management platforms, and relevant GCP (Good Clinical Practice) certifications is commonly required. Attention to detail, proactive communication, and the ability to collaborate effectively across clinical research teams are key soft skills. These competencies ensure regulatory compliance and seamless documentation, which are critical for the successful conduct and audit-readiness of clinical trials.

What is a Trial Master File job?

A Trial Master File (TMF) job involves managing and maintaining essential documents related to clinical trials to ensure compliance with regulatory requirements. Professionals in this role organize, track, and audit critical trial documentation to support inspections and submissions. They work closely with clinical teams, sponsors, and regulatory authorities to ensure proper documentation is accurate, complete, and audit-ready throughout the trial lifecycle.

What are the typical responsibilities and daily tasks of a Trial Master File (TMF) Specialist?

As a TMF Specialist, your main responsibilities include managing, organizing, and maintaining all essential clinical trial documentation to ensure compliance with regulatory standards. On a daily basis, you will review and upload documents to eTMF systems, track document status, resolve discrepancies, and support study teams during audits or inspections. You'll collaborate closely with clinical research associates, project managers, and quality assurance teams to ensure the TMF is complete and inspection-ready at all times. The work is detail-oriented and deadline-driven, offering opportunities to develop expertise in regulatory standards and advance into roles such as TMF Manager or Clinical Trial Associate.

What is the salary of trial master file?

The Trial Master File (TMF) role typically offers a salary range between $60,000 and $100,000 annually, depending on experience, location, and the size of the organization. Professionals in this field often have skills in document management, regulatory compliance, and clinical trial processes, which can influence compensation.

What jobs pay 2000 a day?

High-paying jobs that can pay around $2,000 a day often include specialized roles such as trial master file managers in clinical research, senior consultants, or freelance professionals like consultants, surgeons, or legal experts. These roles typically require advanced skills, certifications, or extensive experience and may involve project-based or contract work with high hourly or daily rates.

Can you be a CRA with no experience?

A Clinical Research Associate (CRA) typically requires some prior knowledge of clinical trial processes, regulations, and monitoring techniques. While entry-level positions may be available, most employers prefer candidates with relevant education or experience in healthcare, life sciences, or related fields, along with familiarity with electronic data capture tools and Good Clinical Practice (GCP) guidelines.

What jobs pay $500,000 a year in the US?

High-level roles related to managing clinical trials, such as Trial Master File managers or directors, typically do not reach $500,000 annually. Executive positions in pharmaceutical companies, biotech firms, or clinical research organizations, such as Chief Medical Officers or Vice Presidents, are more likely to earn this level of compensation, often including bonuses and stock options. These roles require extensive experience, advanced degrees, and leadership skills in the industry.
What are the most commonly searched types of Trial Master File jobs in Raleigh, NC? The most popular types of Trial Master File jobs in Raleigh, NC are:
What are popular job titles related to Trial Master File jobs in Raleigh, NC? For Trial Master File jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Trial Master File jobs in Raleigh, NC look for? The top searched job categories for Trial Master File jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Trial Master File jobs? Cities near Raleigh, NC with the most Trial Master File job openings:
Trial Master File jobs near you
Clinical Trial Assistant

Clinical Trial Assistant

IQVIA

Durham, NC • On-site

$34K - $118K/yr

Full-time

This job post has expired today. Applications are no longer accepted.

IQVIA rating

8.2

Company rating: 8.2 out of 10

Based on 52 frontline employees who took The Breakroom Quiz

45th of 204 rated it services

Job description

Essential Functions
Assist Clinical Research Associates (CRAs) and Regulatory and Start-Up (RSU) team with accurately updating and maintaining clinical documents and systems (e.g., Trial Master File (TMF)) that track site compliance and performance within project timelines.
Assist the clinical team with the preparation, handling, distribution, filing, and archiving of clinical documentation and reports according to the scope of work and standard operating procedures.
Assist with periodic review of study files for completeness.
Assist CRAs and RSU with preparation, handling and distribution of Clinical Trial Supplies and maintenance of tracking information.
Assist with the tracking and management of Case Report Forms (CRFs), queries and clinical data flow.
Act as a central contact for the clinical team for designated project communications, correspondence and associated documentation.
May accompany CRAs on site visits to assist with clinical monitoring duties upon completion of required training.
Qualifications
Bachelor's DegreeRequired
3 years administrative support experience.
Equivalent combination of education, training and experience.
Computer skills including working knowledge of Microsoft Word, Excel and PowerPoint.
Written and verbal communication skills including good command of English language.
Effective time management and organizational skills.
Ability to establish and maintain effective working relationships with coworkers, managers, and clients.
Awareness of applicable clinical research regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines as provided in company training.
Knowledge of applicable protocol requirements as provided in company training.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more athttps://jobs.iqvia.com

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $34,400.00 - $118,600.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

What IQVIA employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

IQVIA logo

About IQVIA

Sourced by ZipRecruiter

At IQVIA, we are passionate about helping customers and partners improve results and patient outcomes. Everything we do contributes to this vision for creating a healthier world. In today’s healthcare environment, it’s not only about how much data, information, and technology you have at your fingertips – it’s what you do with it. IQVIA is focused on making intelligent connections for customers across the entire healthcare ecosystem to help you drive healthcare forward. Whether that means partnering with novel technology companies to boost patient engagement, leveraging AI & machine learning to accelerate results, or using decentralized trials to reach the right patients wherever they are – we are always looking for smarter ways to move you forward.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Durham, NC, US

View All IQVIA Jobs

Apply