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Trial Master File Jobs in Raleigh, NC (NOW HIRING)

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

... in the Trial Master File to ensure inspection readiness. • Assist in the development of study documents and tools including informed consent forms, project plans, budgets, logs, templates ...

Fortrea

TMF Lead II - FSP - US

Durham, NC · On-site

$30.25 - $41.50/hr

The TMF Management team is responsible for the completeness and accuracy of the Trial Master File (TMF) for all sponsored studies. The TMF Lead II is the Subject Matter Expert for TMF across all ...

Fortrea

TMF Lead II - FSP - US

Durham, NC · Remote

$32.25 - $44.25/hr

The TMF Management team is responsible for the completeness and accuracy of the Trial Master File (TMF) for all sponsored studies. The TMF Lead II is the Subject Matter Expert for TMF across all ...

Veranex

Sr Clinical Research Associate

Raleigh, NC · On-site

$98K - $140K/yr

Supports and maintains documentation of all clinical research activities in the study trial master file (TMF), e.g., monitoring reports, site correspondence, device inventory information. * Drives ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

System One

Clinical Study Manager

Durham, NC · On-site

... the Trial Master File, including accurate filing, reconciliation, ongoing review, and execution of quality control activities. * Draft, review, and/or approve study-related documents, including ...

IQVIA

CRA 2, Oncology, IQVIA

Durham, NC

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA, Inc.

CRA 2, Oncology, IQVIA

Durham, NC · On-site

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

CRA 2, Oncology, IQVIA

Durham, NC

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

Syneos Health

CTM - Future Roles (US)

Morrisville, NC · On-site

Reconciles contents of the ISF with the Trial Master File (TMF). Ensures the investigator/physician site is aware of the requirement of archiving essential documents in accordance with local ...

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Trial Master File information

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How much do trial master file jobs pay per hour?

As of Aug 4, 2026, the average hourly pay for trial master file in Raleigh, NC is $38.39, according to ZipRecruiter salary data. Most workers in this role earn between $24.86 and $46.70 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the trial master file position, and why are they important?

To thrive in a Trial Master File (TMF) Specialist role, you need meticulous organizational skills, comprehensive knowledge of regulatory requirements for clinical trials, and often a bachelor's degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, document management platforms, and relevant GCP (Good Clinical Practice) certifications is commonly required. Attention to detail, proactive communication, and the ability to collaborate effectively across clinical research teams are key soft skills. These competencies ensure regulatory compliance and seamless documentation, which are critical for the successful conduct and audit-readiness of clinical trials.

What is a trial master file?

A Trial Master File (TMF) job involves managing and maintaining essential documents related to clinical trials to ensure compliance with regulatory requirements. Professionals in this role organize, track, and audit critical trial documentation to support inspections and submissions. They work closely with clinical teams, sponsors, and regulatory authorities to ensure proper documentation is accurate, complete, and audit-ready throughout the trial lifecycle.

What are the typical responsibilities and daily tasks of a trial master file specialist?

As a TMF Specialist, your main responsibilities include managing, organizing, and maintaining all essential clinical trial documentation to ensure compliance with regulatory standards. On a daily basis, you will review and upload documents to eTMF systems, track document status, resolve discrepancies, and support study teams during audits or inspections. You'll collaborate closely with clinical research associates, project managers, and quality assurance teams to ensure the TMF is complete and inspection-ready at all times. The work is detail-oriented and deadline-driven, offering opportunities to develop expertise in regulatory standards and advance into roles such as TMF Manager or Clinical Trial Associate.

What are the most commonly searched types of Trial Master File jobs in Raleigh, NC? The most popular types of Trial Master File jobs in Raleigh, NC are:
What are popular job titles related to Trial Master File jobs in Raleigh, NC? For Trial Master File jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Trial Master File jobs in Raleigh, NC look for? The top searched job categories for Trial Master File jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Trial Master File jobs? Cities near Raleigh, NC with the most Trial Master File job openings:
Trial Master File jobs near you
Infographic showing various Trial Master File job openings in Raleigh, NC as of July 2026, with employment types broken down into 78% Full Time, 18% Part Time, 1% Temporary, and 3% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $79,855 per year, or $38.4 per hour.

Associate Scientist, Laboratory Operations

IQVIA

Durham, NC • On-site

$42K - $89K/yr

Full-time

This job post has expired 1 day ago. Applications are no longer accepted.

IQVIA rating

8.1

Company rating: 8.1 out of 10

Based on 53 frontline employees who took The Breakroom Quiz

59th of 221 rated it services

Job description

We are seeking Associate Scientist, Laboratory Operations to join IQVIA Laboratories at Durham, NC.
We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.
Job Summary:
Perform routine laboratory analysis and testing procedures while supporting accurate documentation, study file maintenance, and Trial Master File delivery. Assist clinical and regulatory teams with documentation, systems updates, tracking activities, and project communications to support compliant study execution.
What You'll Be Doing:
  • Perform routine analysis and laboratory testing procedures to obtain data from client specimens
  • Provide timely documentation and review of work performed in accordance with applicable procedures
  • Assist Clinical Research Associates and Regulatory and Start-Up teams with updating and maintaining clinical documents and systems, including the Trial Master File
  • Support preparation, handling, distribution, filing, and archiving of clinical documentation and reports
  • Assist with periodic review of study files for completeness
  • Coordinate tracking and management of Case Report Forms, queries, clinical data flow, and clinical trial supplies
  • Serve as a central contact for designated project communications, correspondence, and associated documentation
  • Complete various laboratory tasks including inventory, equipment maintenance, general maintenance logs, cell culture, assay training, data compilation, and scheduling support
What We Are Looking For:
  • High School Diploma or equivalent required
  • Years of experience in relevant fields - 3-4 years administrative support experience
  • Minimum one year clinical research experience strongly preferred
  • Computer skills including working knowledge of Microsoft Word, Excel and PowerPoint
  • Basic knowledge of applicable clinical research regulatory requirement, i.e., Good Clinical Practice and International Conference on Harmonization guidelines as provided in company training
  • Knowledge of applicable protocol requirements as provided in company training
  • Experience with Trial Master File maintenance, clinical documentation, Case Report Forms, queries, and clinical data flow tracking
  • Other equivalent combination of education, training, and experience may be accepted in lieu of degree
The Knowledge, Skills and Abilities Needed for This Role:
  • Written and verbal communication skills including good command of English language
  • Effective time management and organizational skills
  • Ability to establish and maintain effective working relationships with coworkers, managers, and clients
  • Strong attention to detail when reviewing, filing, archiving, and maintaining study documentation
  • Ability to support multiple project communications, documentation workflows, and laboratory operations activities within project timelines
What We Offer You:
We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees' physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey.
To learn more about our benefits, visit IQVIA benefits.
If you're looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible!

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more athttps://jobs.iqvia.com

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $42,700.00 - $89,000.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

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About IQVIA

Sourced by ZipRecruiter

At IQVIA, we are passionate about helping customers and partners improve results and patient outcomes. Everything we do contributes to this vision for creating a healthier world. In today’s healthcare environment, it’s not only about how much data, information, and technology you have at your fingertips – it’s what you do with it. IQVIA is focused on making intelligent connections for customers across the entire healthcare ecosystem to help you drive healthcare forward. Whether that means partnering with novel technology companies to boost patient engagement, leveraging AI & machine learning to accelerate results, or using decentralized trials to reach the right patients wherever they are – we are always looking for smarter ways to move you forward.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Durham, NC, US

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