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Technology Program Manager Jobs in Columbia, SC (NOW HIRING)

Mentis Systems

Engineering Program Manager

Sumter, SC · On-site

$103K/yr

One of the largest global medical technology companies in the world, the role of the Global Integrated Engineering Program Manager is pivotal. This position is at the heart of our mission to advance ...

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Lead Technical Program Manager

North, SC · On-site +1

$119K - $155K/yr

Attackers can evade endpoint detection, firewalls and many other technologies - but they can't ... As a Technical Program Manager for Labs, you are the architect of predictability in a world of ...

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All JobsTechnology Program JobsTechnology Program Manager JobsTechnology Program Manager Jobs in Columbia, SC

Technology Program Manager information

See Columbia, SC salary details

$18

$42

$64

How much do technology program manager jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for technology program manager in Columbia, SC is $42.12, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $50.05 per hour, depending on experience, location, and employer.

What is the difference between Technology Program Manager vs Project Manager?

AspectTechnology Program ManagerProject Manager
CredentialsTypically requires PMP, PgMP, or similar certificationsOften requires PMP or CAPM certifications
Work EnvironmentManages multiple related projects within tech programsFocuses on individual projects with specific deliverables
Industry UsageCommon in tech companies, IT departments, and software firmsUsed across various industries including tech, construction, and healthcare

The main difference is that a Technology Program Manager oversees multiple related projects within a technology program, focusing on strategic alignment and long-term goals. In contrast, a Project Manager handles specific projects with defined scopes and deliverables. Both roles require similar certifications but differ in scope and responsibilities.

How does a Technology Program Manager typically collaborate with cross-functional teams during a project lifecycle?

A Technology Program Manager works closely with cross-functional teams—including engineering, product management, quality assurance, and business stakeholders—throughout the entire project lifecycle. They facilitate regular meetings to align on project goals, timelines, and deliverables, ensuring transparent communication and quick issue resolution. By acting as a central point of coordination, they help balance conflicting priorities, manage dependencies, and keep all team members accountable for their contributions. This collaborative approach is vital for delivering complex technology initiatives on time and within scope.

What does a Technology Program Manager do?

A Technology Program Manager oversees the planning, execution, and delivery of technology-related projects within an organization. They coordinate cross-functional teams, manage resources, set timelines, and ensure that programs align with business goals. Their role often involves risk management, stakeholder communication, and ensuring that projects are completed on time and within budget. Technology Program Managers play a key part in driving innovation and implementing new technologies to support business growth.

What are the key skills and qualifications needed to thrive as a Technology Program Manager, and why are they important?

To thrive as a Technology Program Manager, you need a strong background in project management, technical expertise, and experience with software development lifecycles, often supported by a bachelor's degree in a related field. Familiarity with tools like Jira, Microsoft Project, and certifications such as PMP or Agile/Scrum Master are commonly required. Exceptional leadership, stakeholder management, and communication skills help drive cross-functional teams toward shared goals. These abilities are crucial for ensuring that complex technology projects are delivered successfully, on time, and within budget.
What job categories do people searching Technology Program Manager jobs in Columbia, SC look for? The top searched job categories for Technology Program Manager jobs in Columbia, SC are:
What cities near Columbia, SC are hiring for Technology Program Manager jobs? Cities near Columbia, SC with the most Technology Program Manager job openings:
Technology Program Manager jobs near you
Manufacturing Science & Technology Program Manager

Manufacturing Science & Technology Program Manager

Nephron Pharmaceuticals

West Columbia, SC • On-site

Full-time

Re-posted 8 days ago

Job description

Job Purpose:
The MS&T Program Manager leads and coordinates cross-functional programs that support manufacturing, process robustness, and lifecycle management of pharmaceutical products. This role serves as a critical bridge between Manufacturing, Quality, R&D, and Engineering, ensuring that processes are scientifically sound, scalable, and continuously improved.
The Program Manager drives initiatives such as technology transfer, process development, process optimization, and new product introduction, ensuring alignment with regulatory requirements and business objectives. This position plays a key role in maintaining a state of control across commercial manufacturing while enabling innovation and operational excellence.
Essential Duties and Responsibilities:
  • Lead and manage MS&T programs and projects, ensuring delivery on scope, timelines, and business objectives
  • Serve as the primary coordinator for process and product development activities technology transfer activities, including process scale-up, site transfers, and new product introductions (NPI)
  • Coordinate and lead special projects and cross-functional initiatives, ensuring alignment across Manufacturing, Engineering, Quality, and MS&T
  • Partner with Engineering and Quality to ensure timely change control execution, including impact assessments, implementation plans, and closure activities
  • Coordinate and oversee process development and process improvement studies, including experimental design, execution, and data analysis
  • Act as a central point of contact for engineering-driven initiatives, including equipment upgrades, facility modifications, and process improvements
  • Partner with R&D, Manufacturing, and Quality to ensure robust process design and successful commercialization of new products
  • Process performance monitoring, including trend analysis, statistical evaluation, and identification of improvement opportunities
  • Lead cross-functional investigations into process deviations, non-conformances, and out-of-trend results, ensuring root cause identification and effective CAPAs
  • Support and optimize aseptic and sterile manufacturing processes (including BFS, if applicable), ensuring compliance and process control.
  • Establish and maintain process control strategies, including critical process parameters (CPPs) and critical quality attributes (CQAs) as applicable.
  • Collaborate with Engineering and Manufacturing on process improvements, equipment changes, and scale-up activities
  • Ensure all MS&T activities comply with cGMP, FDA, EMA, and global regulatory requirements
  • Support regulatory filings, supplements, and responses by providing technical and scientific documentation
  • Lead or support risk assessments (e.g., FMEA) to evaluate process changes and improvements
  • Drive continuous improvement initiatives using data-driven and Lean/Six Sigma methodologies
  • Oversee knowledge management and technical documentation, ensuring accurate and compliant records
  • Manage program budgets, resources, and timelines, ensuring efficient execution of MS&T initiatives
  • Provide technical leadership and mentorship to MS&T engineers and project team members.
  • Act as a key point of contact during regulatory inspections and audits for MS&T-related topics
  • Supplemental Functions:
  • Provide escalation support for critical operational issues impacting production output or customer delivery commitments
  • Drive a culture of operational excellence, accountability, and continuous improvement across all functions

Requirements
Knowledge & Skills:
• Deep knowledge of pharmaceutical manufacturing and distribution regulations, including cGMP, FDA guidelines, and GDP
• Strong expertise in manufacturing operations, production planning, inventory control and end-to-end supply chain logistics
• Understanding of manufacturing systems, WMS, ERP platforms, automation technologies, and data analytics
• Proven ability to lead and develop cross-functional teams in manufacturing and supply chain environments
• Strong problem-solving in regulated, high-stakes environments
• Excellent collaboration and communication skills across Manufacturing, Quality, Regulatory, and Supply Chain functions
• Experience with Lean, Six Sigma, or similar continuous improvement methodologies
• High attention to detail and organizational skills to ensure quality, traceability, and audit readiness at all times
Education/Experience:
• Bachelor's or Master's in engineering, life sciences, or related field.
• 5-10+ years in MS&T, manufacturing, or process development
• 2-5+ years in program/project management roles Demonstrated experience in pharmaceutical or sterile manufacturing environments, preferably including aseptic processing or BFS (blow-fill-seal) technologies
• Strong background in driving operational efficiencies
• Experience leading continuous improvement initiatives using Lean, Six Sigma, or similar methodologies (certification is often preferred)
• Prior involvement in regulatory inspections, internal/external audits, and handling of deviations, CAPAs, recalls, and product investigations
• Experience supporting product launches, scale-up activities, and supply chain integration during periods of growth or organizational change
Working Conditions / Physical Requirements:
  • This position requires bending, typing, lifting (up to 40 1bs.), standing, sitting and walking throughout the facility.

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