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Sr Manager Clinical Operations Jobs (NOW HIRING)

Iota Biosciences

Manager, Clinical Operations

Alameda, CA · On-site

$145K - $200K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Role We're seeking a Manager of Clinical Operations to lead the oversight, planning, coordination, and execution of clinical projects for our Class III active implantable device program. This ...

Jj

Manager, Clinical Operations

Spring House, PA · On-site +1

  • Retirement

  • PTO

Reports to Director Clinical Operations/Director Operations TA Head, Sr Manager Clinical Operations or County Head or equivalent * Primary interfaces: LTMs, SMs, CTAs, Country Head, other Functional ...

Johnson & Johnson

Manager, Clinical Operations

Raritan, NJ · On-site +1

  • Retirement

  • PTO

Reports to Director Clinical Operations/Director Operations TA Head, Sr Manager Clinical Operations or County Head or equivalent * Primary interfaces: LTMs, SMs, CTAs, Country Head, other Functional ...

Jj

Manager, Clinical Operations

Raritan, NJ · On-site +1

  • Retirement

  • PTO

Reports to Director Clinical Operations/Director Operations TA Head, Sr Manager Clinical Operations or County Head or equivalent * Primary interfaces: LTMs, SMs, CTAs, Country Head, other Functional ...

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How much do sr manager clinical operations jobs pay per year?

As of Aug 16, 2026, the average yearly pay for sr manager clinical operations in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by a Sr Manager Clinical Operations, and how can they be addressed?

A Sr Manager Clinical Operations often encounters challenges such as coordinating cross-functional teams, ensuring regulatory compliance, and managing multiple clinical trial timelines simultaneously. Balancing the needs of various stakeholders—such as sponsors, investigators, and regulatory bodies—requires strong communication and leadership skills. Staying organized with robust project management tools and fostering transparent communication within the team can help address these challenges effectively. Additionally, proactively identifying potential risks and implementing mitigation strategies is key to maintaining smooth clinical trial operations.

What is the difference between Sr Manager Clinical Operations vs Clinical Project Manager?

AspectSr Manager Clinical OperationsClinical Project Manager
CredentialsTypically requires a Bachelor's or Master's in Life Sciences, with experience in clinical operationsRequires similar educational background, often with certifications like PMP
Work EnvironmentOversees multiple projects, manages teams, and ensures compliance across clinical trialsFocuses on managing individual clinical projects, timelines, and deliverables
Employer & Industry UsageCommon in pharmaceutical, biotech, and CRO companies for operational leadershipUsed in similar settings, often as a project-focused role within clinical research teams

The Sr Manager Clinical Operations typically has broader responsibilities overseeing multiple projects and teams, while the Clinical Project Manager concentrates on managing specific clinical trials. Both roles require similar credentials and are vital in clinical research, but differ in scope and focus.

What are the key skills and qualifications needed to thrive as a Sr Manager Clinical Operations, and why are they important?

To thrive as a Sr Manager Clinical Operations, you need a strong background in clinical research, project management, and regulatory compliance, typically supported by a degree in life sciences or a related field and extensive experience in clinical trials. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and GCP guidelines is essential, and certifications such as PMP or ACRP are often preferred. Exceptional leadership, strategic thinking, and communication skills help you effectively lead teams and manage complex projects. These capabilities are crucial for ensuring efficient trial execution, regulatory adherence, and the delivery of high-quality clinical outcomes.

What is a Sr Manager Clinical Operations?

A Sr Manager Clinical Operations is a senior professional responsible for overseeing the planning, execution, and management of clinical trials and studies within a healthcare or pharmaceutical organization. They ensure that clinical projects are conducted efficiently, comply with regulatory standards, and meet organizational goals. This role involves leading clinical operations teams, managing budgets and timelines, and collaborating with cross-functional departments. Sr Managers also play a key role in process improvement and maintaining high standards of data quality and patient safety.
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Sr Manager Clinical Operations jobs near you
Infographic showing various Sr Manager Clinical Operations job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 67% In-person, and 33% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.

Manager, Clinical Operations

Meridian Bioscience, Inc.

Cincinnati, OH • On-site

Other

Re-posted yesterday

Job description

About Meridian
Meridian Bioscience is a fully integrated life science company that develops, manufactures, markets and distributes a broad range of innovative diagnostic products. We are dedicated to developing and delivering better solutions that give answers with speed, accuracy and simplicity that are redefining the possibilities of life from discovery to diagnosis. We are looking for talented and passionate individuals that help drive our vision. Our innovative culture will allow interested candidates to discover and create, through collaboration, cutting edge solutions to tough problems.
Job Summary
The Manager, Clinical Operations is a seasoned professional with wide-ranging experience and a thorough understanding of clinical study management, biospecimen acquisition, FDA and ICH regulations and Good Clinical Practices (GCP). The candidate must be self-motivated, able to work and lead in a remote team environment and be able to establish strong, positive relationships with both internal departments, external clinical study sites and biospecimen vendors.
The successful candidate contributes to the development of Clinical Affairs processes and procedures at the project and company levels pertaining to Clinical Operations involvement in our clinical studies. The Manager, Clinical Operations will provide leadership and career development, mentoring and training for CRA, biorepository and clinical trial logistics staff as well as is responsible for Clinical Operations staff resourcing.
Key Duties
Tasks/Duties/Responsibilities:
  • Manage and facilitate the personal development of CRAs, including fostering career growth, and providing relevant company-specific, ethical, and regulatory trainings. Serves as a mentor and guide to junior employees. In addition, oversee the personal development of clinical trial logistics and biorepository personnel.
  • Partner with the Clinical Affairs Director to create and implement the strategic vision for the Clinical Operations team to ensure the high-quality end-to-end management of clinical trials, clinical trial logistics and internal/external biospecimen acquisition.
  • Lead Clinical Operations level initiatives for the development, maintenance and implementation of processes, tools, templates and plans.
  • Regularly monitor the overall health of the clinical studies from the study initiation to closure including regular evaluation of key metrics (enrollment, site activation), monitoring and escalation of project risks and mitigation plans when appropriate.
  • Lead and prepare the content for internal meetings with leadership, internal cross functional teams and external collaborators.
  • Functions as a working manager and takes on CRA responsibilities, as needed
  • Oversee CRAs during site visits (site initiation visit, interim monitoring visits and close-out visits), as needed.
  • Oversee the clinical operations aspects of timely data monitoring and partner with Clinical Affairs team leaders and study sites regarding generation and reconciliation of queries to ensure business timelines are met.
  • Direct the creation and collection of required study documents both internally and with the investigational study sites.
  • Responsible for all aspects of the biospecimen acquisition program, including forecasting and managing resources, timelines and budgets for external and internal biospecimen acquisition.
  • Implement strategies and best practices for the Clinical Operations team to build and maintain relationships with investigational study sites and vendors.
  • Responsible for resource allocation for the Clinical Operations team for assigned projects.
  • Travel: 30%
  • Other duties as assigned.

Qualifications
  • B.S. in Biological/Health Sciences or related Scientific fields; master's degree preferred
  • Certificate of completion from a Clinical Research Associate program is preferred
  • Minimum of 5 years of experience mentoring, managing, and leading a team
  • Minimum of 5 years experience as a CRA and/or Lead CRA
  • Minimum of 1-2 years experience with managing and/or working in clinical trial logistics and/or biorepository operations.
  • Experience with internal sample collection is preferred.
  • Basic knowledge in the areas of microbiology, immunology or molecular biology and biochemistry as related to infectious diseases.
  • Thorough knowledge of FDA, ICH and GCP guidelines
  • Strong knowledge and experience with TMF/eTMF, EDC systems and CTMS preferred.
  • Be an initiative-taker, detail oriented, organized, and able to prioritize and balance workloads to meet strict critical deadlines along with performing under pressure in a fast- paced environment.
  • Highly motivated, readily adapts to changing priorities.
  • Excellent organizational skills with high attention to detail is required.
  • Able to work successfully under tight timelines.
  • Ability to manage, prioritize, and routinely report progress on multiple projects to cross functional teams and Clinical Management.
  • Ability to read, understand and follow all company SOPs and guidelines and ensures compliance in direct reports.

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