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Sr Clinical Research Associate Jobs in Raleigh, NC

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Clinical Research Associate II

Raleigh, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

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Clinical Research Associate II

Raleigh, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

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Clinical Research Associate II

Cary, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

IQVIA

Clinical Research Associate 2, IQVIA

Durham, NC · On-site

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH/NASH, dermatology and/or asthma/respiratory clinical trials. Women's Health experience is a plus! Job ...

IQVIA

Clinical Research Associate 2, IQVIA

Durham, NC · On-site

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH/NASH, dermatology and/or asthma/respiratory clinical trials. Women's Health experience is a plus! Job ...

IQVIA, Inc.

Clinical Research Associate 2, IQVIA

Durham, NC · On-site

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH/NASH, dermatology and/or asthma/respiratory clinical trials. Women's Health experience is a plus! Job ...

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

What You'll Do As a senior clinical research professional, you will lead and support complex clinical trials throughout the study lifecycle while serving as a trusted resource for research teams ...

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

What You'll Do As a senior clinical research professional, you will lead and support complex clinical trials throughout the study lifecycle while serving as a trusted resource for research teams ...

IQVIA

Clinical Research Associate

Durham, NC · On-site

$87K - $182K/yr

Req Good knowledge of, and skill in applying, applicable clinical research regulatory requirements. i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines.

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All JobsSr Clinical Research Associate JobsSr Clinical Research Associate Jobs in Raleigh, NC

Sr Clinical Research Associate information

See Raleigh, NC salary details

$35K

$91.7K

$139.5K

How much do sr clinical research associate jobs pay per year?

As of Sep 4, 2026, the average yearly pay for sr clinical research associate in Raleigh, NC is $91,681.00, according to ZipRecruiter salary data. Most workers in this role earn between $60,800.00 and $124,400.00 per year, depending on experience, location, and employer.

What is a Sr Clinical Research Associate?

A Sr Clinical Research Associate (Senior CRA) is an experienced professional responsible for overseeing clinical trials to ensure they comply with regulatory requirements, protocols, and Good Clinical Practice (GCP) guidelines. They monitor study sites, review data, ensure participant safety, and act as a liaison between the sponsor and clinical sites. Senior CRAs often mentor junior staff, manage multiple studies, and contribute to improving clinical trial processes. Their role is vital in bringing new medical treatments and devices from research to market.

What are the key skills and qualifications needed to thrive as a Sr Clinical Research Associate?

To thrive as a Sr Clinical Research Associate, you need a robust background in clinical research, regulatory compliance, and study monitoring, usually supported by a bachelor's degree in life sciences and significant industry experience. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and certifications such as ACRP or SOCRA are highly valued. Outstanding attention to detail, strong organizational skills, and effective communication enable successful oversight of trial sites and collaboration with study teams. These skills are vital for ensuring the integrity, safety, and compliance of clinical trials, directly impacting study outcomes and regulatory approval.

What are some common challenges faced by a Sr Clinical Research Associate when monitoring multiple clinical trial sites?

As a Sr Clinical Research Associate (CRA), juggling multiple trial sites can be challenging due to varying site compliance levels, differing investigator engagement, and diverse patient populations. You may encounter issues such as inconsistent data entry, protocol deviations, and varying levels of site staff training. Effective time management, strong communication skills, and a proactive approach to problem-solving are essential to ensure all sites adhere to protocols and timelines. Additionally, frequent travel and adapting to each site's workflow can add complexity, but these challenges also provide valuable opportunities for professional growth.

What is the difference between Sr Clinical Research Associate vs Clinical Research Associate?

AspectSr Clinical Research AssociateClinical Research Associate
Required credentialsBachelor's degree, experience, often certifications like CCRP or RACBachelor's degree, entry-level or less experience, certifications optional
Work environmentPharmaceutical companies, CROs, clinical trial sitesSimilar settings, often entry-level roles in clinical trials
Employer and industry usageUsed in pharmaceutical and biotech industries, more senior rolesCommon in clinical research, entry to mid-level roles
Search and comparison intentOften searched for career progression or senior rolesOften searched for entry-level positions or understanding roles

The main difference between a Sr Clinical Research Associate and a Clinical Research Associate lies in experience, responsibilities, and qualifications. The senior role typically requires more experience, certifications, and involves overseeing complex trials, while the CRA is often an entry-level or mid-level position focused on supporting clinical trial activities.

What are the most commonly searched types of Sr Clinical Research jobs in Raleigh, NC?

The most popular types of Sr Clinical Research jobs in Raleigh, NC are:

What are popular job titles related to Sr Clinical Research Associate jobs in Raleigh, NC?

For Sr Clinical Research Associate jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Sr Clinical Research Associate jobs in Raleigh, NC look for?

The top searched job categories for Sr Clinical Research Associate jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Sr Clinical Research Associate jobs?

Cities near Raleigh, NC with the most Sr Clinical Research Associate job openings:

Sr Clinical Research Associate jobs near you
Infographic showing various Sr Clinical Research Associate job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, 1% Temporary, and 1% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $91,681 per year, or $44.1 per hour.

Clinical Research Associate - Full-Service

Syneos Health, Inc.

Morrisville, NC • On-site

$60 - $80/hr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago

New

Key responsibilities

  • Manage site qualification, monitoring, management, and close-out activities across the study lifecycle to ensure compliance with regulatory standards.

  • Verify informed consent processes, assess safety and data integrity issues, and review source documents and CRF data accuracy.

  • Manage investigational product inventory, reconcile storage and dispensation, and support audit readiness and study documentation.

Syneos Health rating

8.1

Company rating: 8.1 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

39th of 86 rated pharmaceutical

Job description

Clinical Research Associate - Full-Service

Updated: Yesterday
Location: Morrisville, NC, United States
Job ID:25109785-OTHLOC-1500-2DCT-2DR

Description

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization that accelerates customer success. As a Clinical Research Associate – Full Service you will be responsible for managing site qualification, monitoring, management, and close‑out activities across the study lifecycle, ensuring compliance with ICH‑GCP, GPP and company SOPs. You will collaborate with investigators, study teams and sponsors to maintain study integrity and support clinical trial success.

Job Responsibilities
  • Perform site qualification, initiation, interim monitoring, management activities and close‑out visits (on‑site or remotely) ensuring regulatory, ICH‑GCP and Good Pharmacoepidemiology Practice compliance.
  • Verify informed consent processes and protect subject confidentiality; assess safety and data integrity issues at investigator sites.
  • Follow the Clinical Monitoring/Site Management Plan to assess site processes, conduct source document review, verify CRF data accuracy, resolve queries and support electronic data capture requirements.
  • Manage investigational product inventory and reconciliation, ensuring proper dispensation, storage and handling.
  • Review the Investigator Site File for accuracy and completeness, and reconcile with the Trial Master File.
  • Document activities via confirmation letters, follow‑up letters, trip reports and communication logs per SOPs; support recruitment, retention and awareness strategies.
  • Manage project‑level site activities, budgets and timelines; act as primary liaison with site personnel and the Central Monitoring Associate.
  • Attend Investigator Meetings and sponsor face‑to‑face meetings; participate in global monitoring and training sessions.
  • Assist in audit readiness and support audit preparation and follow‑up actions.
  • Maintain up‑to‑date knowledge of ICH‑GCP, regulations and SOPs; complete required training.
  • Support study lifecycle activities, including study identification through close‑out and real‑world late‑phase study designs; train junior staff and identify out‑of‑scope activities.
Qualifications
  • Bachelor’s degree or RN in a related field, or equivalent combination of education, training and experience.
  • Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements.
  • Strong computer skills and ability to adopt new technologies.
  • Excellent communication, presentation and interpersonal skills.
  • Ability to travel up to 75% of the time.
  • U.S. only: compliance with Site access data requirements as part of employment.
Benefits and Compensation

This position may include a company car or car allowance, health benefits (medical, dental, vision), company match 401(k), employee stock purchase plan eligibility, commissions/bonus potential, and flexible paid time off. Eligibility for paid sick time may vary by location. Salary will vary based on qualifications, skills and proficiency.

Equal Opportunity Employer

Syneos Health is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants in performing the essential functions of the job.

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