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Clinical Research Operations Manager Jobs in Raleigh, NC

NCSU

Research Operations Manager II

Raleigh, NC

Posting Information Posting Number PG194299EP Internal Recruitment No Working Title Research Operations Manager II Anticipated Hiring Range $65,000 - $70,600 Work Schedule Mon-Fri, 8am-5pm Job ...

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

As a Clinical Research Coordinator in the Ophthalmology Clinical Research Unit (CRU) , you will ... Investigational Product & Study Operations * Manage all aspects of investigational product ...

Duke University

Clinical Research Coordinator

Durham, NC

$23.50 - $31.25/hr

As a Clinical Research Coordinator in the Ophthalmology Clinical Research Unit (CRU) , you will ... Investigational Product & Study Operations * Manage all aspects of investigational product ...

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

Clinical Trial Operations * Coordinate and manage complex clinical research studies, including drug, device, and procedural trials involving randomization, blinding, crossover designs, and ...

Duke University

Clinical Research Coordinator

Durham, NC

$23.50 - $31.25/hr

Clinical Trial Operations * Coordinate and manage complex clinical research studies, including drug, device, and procedural trials involving randomization, blinding, crossover designs, and ...

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Clinical Research Operations Manager information

See Raleigh, NC salary details

$30.9K

$86.6K

$164.7K

How much do clinical research operations manager jobs pay per year?

As of Aug 28, 2026, the average yearly pay for clinical research operations manager in Raleigh, NC is $86,560.00, according to ZipRecruiter salary data. Most workers in this role earn between $64,000.00 and $100,200.00 per year, depending on experience, location, and employer.

What does a clinical research operations manager do?

A Clinical Research Operations Manager oversees the daily operations of clinical trials to ensure they are conducted efficiently, ethically, and in compliance with regulatory standards. They coordinate between research staff, sponsors, and regulatory bodies, manage budgets and timelines, and ensure proper documentation and reporting. Their role is essential in maintaining the quality and integrity of clinical studies from start to finish.

How does a clinical research operations manager collaborate with cross-functional teams during a study?

As a Clinical Research Operations Manager, you will work closely with cross-functional teams including clinical trial coordinators, data managers, regulatory affairs specialists, and principal investigators. Your role involves facilitating clear communication between departments, ensuring that study milestones are met, and resolving operational issues as they arise. Regular meetings and status updates are common, and you'll often act as a liaison to keep all stakeholders aligned on study objectives, timelines, and compliance requirements. This collaborative approach is crucial for maintaining study integrity and ensuring successful trial outcomes.

What are the key skills and qualifications needed to thrive as a clinical research operations manager, and why are they important?

To thrive as a Clinical Research Operations Manager, you need a solid background in clinical research, regulatory compliance, and project management, often supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and certifications such as ACRP or SOCRA are highly valuable. Leadership, problem-solving, and excellent organizational and communication skills help you manage teams and collaborate effectively with stakeholders. These skills and qualities are crucial for ensuring the successful execution of clinical trials while maintaining regulatory standards and operational efficiency.

What are popular job titles related to Clinical Research Operations Manager jobs in Raleigh, NC?

For Clinical Research Operations Manager jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Clinical Research Operations Manager jobs in Raleigh, NC look for?

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What cities near Raleigh, NC are hiring for Clinical Research Operations Manager jobs?

Cities near Raleigh, NC with the most Clinical Research Operations Manager job openings:

Clinical Research Operations Manager jobs near you
Infographic showing various Clinical Research Operations Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 88% Full Time, 10% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $86,560 per year, or $41.6 per hour.

Clinical Operations Manager

UNC-Chapel Hill

Chapel Hill, NC • On-site

Full-time

Medical, Life, Retirement, PTO

Re-posted 28 days ago

University Of North Carolina At Chapel Hill rating

7.5

Company rating: 7.5 out of 10

Based on 48 frontline employees who took The Breakroom Quiz

314th of 625 rated colleges and universities

Job description

Posting Information
Department LCCC - Clinical Trials-426806 Career Area Research Professionals Posting Open Date 06/01/2026 Application Deadline 09/03/2026 Open Until Filled No Position Type Permanent Staff (EHRA NF) Working Title Clinical Operations Manager Appointment Type EHRA Non-Faculty Position Number 20076534, 20010901 Vacancy ID NF0009791 Full Time/Part Time Full-Time Permanent FTE 1 Hours per week 40 Position Location North Carolina, US Hiring Range Salary commensurate with qualifications Proposed Start Date 06/29/2026
Position Information
Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.
One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.
University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.
Primary Purpose of Organizational Unit
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.
Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.
Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.
Position Summary
The Clinical Operations Manager provides oversight and management of a large number of clinical research staff to ensure safe, compliant, efficient, and effective conduct of oncology clinical trials. This position provides expert level knowledge in clinical trial practices and regulations. This position works under the direct supervision of the Assistant Director of Clinical Research Operations to ensure safe implementation of oncology clinical trials. The Clinical Operations Manager manages clinical research staff assigned to various disease teams within the Clinical Protocol Office (CPO) providing daily management/supervision, resource and effort allocation, overseeing research compliance and data integrity, and assisting in strategic planning and operational support. This position creates and champions a collaborative and positive relationship dynamic with internal staff and external agencies/organizations.
Minimum Education and Experience Requirements
Master's degree in a discipline related to the field assigned; or Bachelor's degree in a discipline related to the field assigned and two years of research/analysis, preferably with one year in a supervisory role; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Required Qualifications, Competencies, and Experience
Advanced knowledge of ICH GCP, Federal Regulations and Guidelines and ability to follow established regulations, procedures, and protocols; clinical research experience; Experience in interviewing/hiring process and performance management; Possess strong decision-making skills and the ability to problem solve and troubleshoot issues; Strong organizational skills with the ability to manage large volumes of information; High level of accuracy and attention to detail; High level of comfort with technology; Strong computer skills; Ability to gather data and document procedures; Ability to plan work and coordinate multiple projects; Ability to contribute to preparation and delivery of reports, trainings and SOPs; Customer oriented and ability to work within, build and lead a team; Exceptional interpersonal skills and excellent verbal and written communication skills in daily interactions with the ability to interpret and apply UNC policies and federal, state, and local regulations; Ability to work on evenings, weekends and/or holidays occasionally required.
Preferred Qualifications, Competencies, and Experience
Therapeutic clinical trial coordination experience involving drugs and/or devices, to include work in oncology;
SOCRA/ACRP certification;
Supervisory experience;
Experience in Phase I, II, and III clinical research;
Experience navigating medical records and data extraction;
Experience leading a large team.
Special Physical/Mental Requirements Campus Security Authority Responsibilities

Not Applicable.

Special Instructions Quick Link https://unc.peopleadmin.com/postings/319826
Posting Contact Information
Department Contact Name and Title Gretchen Harrison Department Contact Telephone or Email gretchen_harrison@med.unc.edu Office of Human Resources Contact Information

If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to employment@unc.edu
Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status.

Equal Opportunity Employer Statement
The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.

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About University of North Carolina at Chapel Hill

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The University of North Carolina at Chapel Hill (UNC-Chapel Hill), located in Chapel Hill, NC, US, is renowned for being one of the leading research institutes in the world. Operating within the education industry, this public research university offers a broad range of undergraduate, graduate, and professional programs across various disciplines. UNC-Chapel Hill was chartered in 1789 and has maintained its legacy of academic excellence and innovative research for more than two centuries. The institution operates under the core values of excellence, innovation, engagement, accessibility, diversity, and inclusivity. Their mission is to serve the people of North Carolina and the United States by teaching a diverse community of students to become the next generation of leaders.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Chapel Hill, NC, US

Year founded

1789

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