Site Operations Manager Jobs in Reston, VA (NOW HIRING)

Job Title: Associate Director Site Supply Chain

Join AstraZeneca's Cell Therapy Operations as the Associate Director, Site Supply Chain, leading end-to-endplanningand site operationsat our Rockville Manufacturing facility. Reporting to the Site Supply ChainSeniorDirector, you will set and execute the site supply chain strategy to ensure reliable, efficient production and uninterrupted supply of cell therapy products for patients in need. Partnering closely with Manufacturing, Quality, Operations, and Global Supply Chain, you will drive the S&OE cadence, optimize capacity and inventory, enable new product introductions, and embed resilient processes and digital tools across the network. If you bring deepexpertisein supply chain and capacity planning within cell therapy or advanced therapies, this is an opportunity to shape a rapidly scaling platform with meaningful patient impact.

Whatyou'lldo

• End-to-end site operations planning: Lead the integrated site planning process forRockvilleto support clinical and commercial manufacturing, including demand review, capacity evaluation, production scheduling, site slot management, and finite scheduling tooptimizeresources, cycle time, and throughput whilemaintainingcompliance and quality. Ensure on-time availability and deployment of material through planning, scheduling, and replenishment strategies,and bytakingappropriate actionsto prevent supply disruptions. Responsible for maximizing inventory turns while minimizing inventory valuation and scrap.

• Manufacturing capacity andutilizationplanning: Build andmaintainrobust short-, mid-, and long-range capacity scenarios in partnership with Site Operations; balance labor, cleanroom suites, materials, and critical path steps to maximizeutilizationand agility.

• Change leadership: Own supply chaininputs totechnical changes, process improvements, and new product introductions; conduct change assessments, de-risk launches, and ensure supply continuity through scale-up and tech transfer.

• Performance and resilience: Accountable for setting up and leading a robust monthly review process (S&OE) thatvalidatesthe supply plan for the 0-36 monthhorizon. Improve service, inventory, and cost through standard work, process excellence, and digital enablement; implement planning governance, slotting rules, and exception management to strengthen S&OE and response to variability. Build tools for S&OE performance and KPI management to enable continuous improvement of site operations and execution.

• Cross-functional leadership: Lead and coach a high-performing team; align stakeholders across Manufacturing, Quality, MS&T, and Global Supply Chain; communicate clear priorities, risks, and trade-offs to senior leadership.

• Data and systems excellence: Drive maximumutilizationof enterprise software (ERP), demand planning, slotting, and inventory optimization tools; translate complex data into actionable recommendations that elevate site operations.

EssentialSkills andExperience"

• Bachelor's degree with 8+ years of experience, orMaster'sdegree with 6+ years of experience in supply chain, operations, or related disciplines.

• Minimum2+yearsexecuting site supply chain strategies that improve capacity, inventory levels, production efficiency, service levels, and overall reliability.

• Advanced analytical capability with the ability to convert data and scenarios into clear recommendations and plans.

• Demonstratedpeopleleadership and cross-functional influence in GMP manufacturing environments.

• Proficiencywith ERP and advanced planning systems, demand planning and slot management tools, and inventory optimization solutions.

Preferred Skills and Experience:

• Degree in Supply Chain Management, Operations Management, Engineering, Sciences, Business Administration, or related field; advanced degree preferred.

• 10+ years across supply chain planning, demand forecasting, inventory management, and production planning-ideally in pharma/biotech-with specific experience in cell therapy or advanced therapies.

• Strong knowledge of autologous cell therapy supply chains, including Make-to-Order and Make-to-Stock models, vein-to-vein considerations, and cell therapy capacity planning.

• Experience implementing digital planning capabilities, network modeling, or scenario planning in highly regulated, high-mix/low-volume operations.

• APICS/ASCM or equivalent certification preferred

The annual base pay (or hourly rate of compensation) for this position ranges from $ 124,069.60 - 186,104.40 .Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.