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Senior Risk Manager Jobs in Massachusetts (NOW HIRING)

As the First Line Risk Senior Manager, you will represent the first line of defense and identify and mitigate potential risks through the identification, management, and mitigation of the risk and ...

As the First Line Risk Senior Manager, you will represent the first line of defense and identify and mitigate potential risks through the identification, management, and mitigation of the risk and ...

Communicates risk management activities and participates in various institute committees and outcomes to senior leadership and other stakeholders. Collaborates with attorneys from the Office of ...

As the First Line Risk Senior Manager , you will represent the first line of defense and identify and mitigate potential risks through the identification, management, and mitigation of the risk and ...

Lead Risk Manager, Payment Fraud Toronto Onsite | Full-Time | Hybrid after onboarding | Reports to ... For a senior risk professional who wants to operate as a general rather than an analyst, this is ...

As the First Line Risk Senior Manager , you will represent the first line of defense and identify and mitigate potential risks through the identification, management, and mitigation of the risk and ...

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Showing results 1-20

Senior Risk Manager information

See Massachusetts salary details

$24.6K

$129.2K

$229.3K

How much do senior risk manager jobs pay per year?

As of Jul 15, 2026, the average yearly pay for senior risk manager in Massachusetts is $129,153.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,300.00 and $158,400.00 per year, depending on experience, location, and employer.

How much do senior risk managers make?

Senior risk managers typically earn between $90,000 and $150,000 annually, depending on experience, industry, and location. They often hold certifications such as FRM or CRM and work in finance, insurance, or corporate risk management environments.

What does a typical day look like for a Senior Risk Manager?

A Senior Risk Manager’s day often includes analyzing complex data to assess potential financial, operational, or strategic risks and developing mitigation strategies accordingly. You’ll regularly collaborate with business leaders across departments, provide expert advice during project planning, and prepare detailed risk reports for executive management or compliance committees. Additionally, you may oversee junior risk team members, guide audit processes, and participate in risk review meetings. This role offers dynamic daily challenges that require both independent analysis and team-oriented communication, making it ideal for those who enjoy both strategic thinking and hands-on collaboration.

What is the highest paying risk management job?

Senior risk management roles, such as Chief Risk Officer (CRO), tend to be the highest paying positions in risk management, often earning six-figure salaries or more depending on the industry and company size. These roles require extensive experience, advanced certifications like FRM or CRM, and strong leadership skills.

What does a senior risk manager do?

A senior risk manager identifies, assesses, and mitigates potential risks that could impact an organization’s financial health, operations, or reputation. They develop risk management strategies, oversee compliance with regulations, and often use tools like risk assessment software. Strong analytical skills and industry certifications such as FRM or CRM are typically required.

What does a Senior Risk Manager do?

A Senior Risk Manager identifies, assesses, and mitigates potential risks that could impact an organization's financial health, operations, or reputation. They develop risk management strategies, ensure compliance with industry regulations, and collaborate with various departments to implement risk controls. Additionally, they analyze market trends and internal processes to proactively address potential threats. Their goal is to minimize risk exposure while supporting business objectives and long-term sustainability.

What are the key skills and qualifications needed to thrive in the Senior Risk Manager position, and why are they important?

To excel as a Senior Risk Manager, you need strong analytical capabilities, a deep understanding of risk assessment methodologies, and a relevant degree such as finance, economics, or business administration. Familiarity with risk modeling software, governance frameworks (like COSO or ISO 31000), and industry certifications such as FRM or CRM are highly valued. Exceptional communication, leadership, and decision-making skills help distinguish top performers in this role. These abilities are essential for effectively identifying, evaluating, and mitigating potential risks while supporting organizational objectives.

What is the highest salary for a risk manager?

The highest salaries for senior risk managers can exceed $150,000 annually, especially in large financial institutions or corporations in high-cost areas. Factors such as experience, certifications like FRM or PRM, and industry sector influence top-tier compensation levels.
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Sr. Clinical Risk Manager

Sr. Clinical Risk Manager

Deciphera Pharmaceuticals

Waltham, MA • On-site, Remote

$157K - $215K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 21 days ago


Job description

Company Description
Job Description
We are seeking a highly experienced Senior Clinical Risk Manager to lead the execution of our Risk-Based Quality Management (RBQM) strategy across a portfolio of complex clinical trials. In this role, you will partner with cross-functional teams, Clinical Research Organizations (CROs), and key stakeholders to proactively identify, assess, and mitigate risks-ensuring high-quality study delivery and compliance with global regulatory requirements.
This is a highly visible role that requires strong leadership, strategic thinking, and deep RBQM expertise to support study and program-level success.
RBQM Execution & Study Delivery
  • Lead the development and management of study-level risk assessments, including Risk Assessment Categorization Tools (RACTs) and integrated Quality Risk Management Plans (iQRMPs)
  • Maintain risk logs and ensure accurate, real-time tracking of study risks
  • Facilitate periodic risk review meetings and drive proactive risk identification and mitigation
  • Provide expert guidance on site risk levels, study health, and performance trends
  • Define and implement study-specific monitoring strategies, including risk-based monitoring approaches such as targeted SDV or centralized monitoring

Risk Oversight & Reporting
  • Document, communicate, and escalate risks to leadership as appropriate
  • Track, trend, and report Key Risk Indicators (KRIs) to support data-driven decision-making
  • Partner with internal teams and external vendors to manage risks, mitigations, and issue resolution timelines
  • Ensure CROs and service providers adhere to RBQM processes and expectations
  • Support or lead program-level RBQM activities and escalations

Governance, Compliance & Continuous Improvement
  • Serve as a subject matter expert (SME) for RBQM across the organization
  • Ensure adherence to SOPs, work instructions, and regulatory requirements
  • Contribute to ongoing enhancement of RBQM processes and tools
  • Champion a culture of quality, compliance, and continuous improvement

Qualifications
Required Qualifications
  • Bachelor's degree in a scientific or technical discipline (or equivalent experience)
  • 8+ years of Clinical Operations or Development experience, including at least 7 years focused on RBQM
  • Prior in-house RBQM experience
  • Experience operating at the Manager or Senior Manager level within RBQM

Preferred Experience & Skills
  • Strong knowledge of RBQM principles, methodologies, and implementation practices
  • Deep understanding of global clinical research regulations (e.g., ICH-GCP, 21 CFR Part 11)
  • Experience supporting regulatory inspections and audits related to RBQM
  • Proven ability to lead process improvement initiatives
  • Strong collaboration skills with CROs and external partners
  • Excellent communication, problem-solving, and risk management capabilities

Additional Information
Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $157,000 - $215,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.
Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera's competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
Benefits:
  • Competitive salary and annual bonus.
  • Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
  • Generous parental leave and family planning benefits.
  • Outstanding culture and opportunities for personal and professional growth.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.