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Senior Process Safety Engineer Jobs in Charleston, SC

Alcami Corporation

Sr. Process Engineer

Charleston, SC · On-site

$99K - $128K/yr

The Sr. Process Engineer is accountable for driving results in a fast-paced environment by providing technical support for clinical and commercial parenteral Drug Product manufacturing. The Sr. ...

Alcami Corporation

Sr. Process Engineer

Charleston, SC · On-site

$99K - $128K/yr

Job Summary The Sr. Process Engineer is accountable for driving results in a fast-paced environment by providing technical support for clinical and commercial parenteral Drug Product manufacturing.

Alcami Corporation

Sr. Process Engineer

Charleston, SC · On-site

$99K - $128K/yr

Job Summary The Sr. Process Engineer is accountable for driving results in a fast-paced environment by providing technical support for clinical and commercial parenteral Drug Product manufacturing.

PIP Global

Reliability Engineer

Charleston, SC · On-site

$97K - $123K/yr

The Reliability Engineer is responsible for driving equipment reliability, maintainability ... Develop equipment reliability dashboards. 2. Process Safety Management (PSM) Compliance * Ensure ...

RadNet, Inc.

Reliability Engineer

North Charleston, SC · On-site

$90 - $120/hr

Reliability Engineer #3867 Charleston, South Carolina, United States Full-time Job Summary The ... Develop equipment reliability dashboards. 2. Process Safety Management (PSM) Compliance * Ensure ...

Patrick Industries

Process Engineer

Summerville, SC · On-site

Ensure compliance with safety and regulatory standards throughout the manufacturing process. Qualifications: * 3+ years of experience in process engineering, preferably in wire harness or related ...

Patrick Industries

Process Engineer

Summerville, SC

Ensure compliance with safety and regulatory standards throughout the manufacturing process. Qualifications: * 3+ years of experience in process engineering, preferably in wire harness or related ...

JCTM, LLC

Systems Safety Specialist

North Charleston, SC · On-site

$110 - $140/hr

Expand your expertise by supporting advanced C5ISR sensor technologies and applying modern system safety methodologies, hazard‑tracking tools, engineering processes, and defense acquisition ...

New

Alcami Corporation

Process Engineer

Charleston, SC

The Process Engineer is accountable for driving results in a fast-paced environment by providing ... Such personal protective equipment may include, but not limited to safety eyewear, hearing ...

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Senior Process Safety Engineer information

See Charleston, SC salary details

$70.2K

$113.3K

$159.6K

How much do senior process safety engineer jobs pay per year?

As of Aug 21, 2026, the average yearly pay for senior process safety engineer in Charleston, SC is $113,342.00, according to ZipRecruiter salary data. Most workers in this role earn between $97,300.00 and $125,900.00 per year, depending on experience, location, and employer.

What does a senior process safety engineer do?

A Senior Process Safety Engineer is responsible for ensuring that industrial processes, especially those involving hazardous materials, are designed and operated safely to prevent accidents and minimize risks. They analyze operations, conduct safety assessments, and implement systems to comply with safety regulations. Additionally, they lead incident investigations, develop safety procedures, and provide technical guidance to engineering teams to promote a strong safety culture within the organization.

What are the key skills and qualifications needed to thrive as a senior process safety engineer, and why are they important?

To thrive as a Senior Process Safety Engineer, you need a solid background in chemical or process engineering, in-depth knowledge of process safety management (PSM), and typically a bachelor's degree in engineering with relevant certifications like CSP or CCPSC. Familiarity with process hazard analysis (PHA) tools, safety lifecycle software (such as PHA-Pro or BowTieXP), and regulatory standards (OSHA, API) is crucial. Strong analytical thinking, leadership, and effective communication skills help you guide multidisciplinary teams and convey complex safety issues clearly. These competencies are vital to ensure operational safety, regulatory compliance, and the prevention of major incidents in high-risk industrial environments.

What are the main challenges a senior process safety engineer faces when implementing new safety protocols across multiple facilities?

A Senior Process Safety Engineer often encounters challenges such as ensuring consistent application of safety standards across diverse sites, gaining buy-in from cross-functional teams, and adapting protocols to facility-specific hazards. Additionally, balancing regulatory compliance with operational efficiency requires strong communication and project management skills. Successfully addressing these challenges usually involves close collaboration with site managers, operations teams, and regulatory bodies, as well as ongoing training and audits to maintain high safety standards.

What is the difference between Senior Process Safety Engineer vs Process Safety Engineer?

AspectSenior Process Safety EngineerProcess Safety Engineer
CertificationsTypically holds API, NEBOSH, or equivalent certificationsOften requires similar certifications, but less experience needed
Work EnvironmentLeads safety projects, mentors junior staff, and manages complex risk assessmentsSupports safety initiatives, conducts hazard analyses, and assists in safety documentation
Employer & Industry UsageCommon in oil & gas, chemical, and refining industriesUsed across similar industries, often as entry to mid-level role

The main difference between a Senior Process Safety Engineer and a Process Safety Engineer lies in experience, leadership responsibilities, and project scope. Senior professionals typically lead safety initiatives and mentor others, while Process Safety Engineers focus on supporting safety tasks and analysis. Both roles are vital for maintaining safety standards in high-risk industries.

What are the most commonly searched types of Process Safety Engineer jobs in Charleston, SC?

The most popular types of Process Safety Engineer jobs in Charleston, SC are:

What are popular job titles related to Senior Process Safety Engineer jobs in Charleston, SC?

For Senior Process Safety Engineer jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Senior Process Safety Engineer jobs in Charleston, SC look for?

The top searched job categories for Senior Process Safety Engineer jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Senior Process Safety Engineer jobs?

Cities near Charleston, SC with the most Senior Process Safety Engineer job openings:

Senior Process Safety Engineer jobs near you
Infographic showing various Senior Process Safety Engineer job openings in Charleston, SC as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 17% Part Time, 2% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $113,342 per year, or $54.5 per hour.

Sr. Process Engineer

Alcami Corporation

Charleston, SC • On-site

$99K - $128K/yr

Full-time

Re-posted 11 days ago

Alcami rating

7.8

Company rating: 7.8 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

Job description

At Alcami, we deliver reliable solutions that unlock the potential of transformative medicines from discovery to commercialization, through trusted partnership with our clients, recognized industry expertise and proven regulatory track record.

Are you interested in joining our team?


The Sr. Process Engineer is accountable for driving results in a fast-paced environment by providing technical support for clinical and commercial parenteral Drug Product manufacturing. The Sr. Process Engineer’s responsibilities include but are not limited to the following: performing tech transfers of new processes and technologies into the site, preparation of documentation to support process validation and batch manufacturing, troubleshooting manufacturing processes, completing process deviations and investigations, and coordinating lab studies with the formulation development lab. These functions will be executed following standard operating procedures and batch records in accordance with FDA and EU requirements and current Good Manufacturing Practices.


  • 100% on-site position.
  • 1st Shift: Monday - Friday, 8:00am - 5:00pm.

  • Provides technical assistance for process tech transfer and validation efforts for assigned manufacturing projects.
  • Writes Master Batch Records with a strong understanding of equipment, critical process parameters, in-process tests, etc.
  • Monitors manufacturing processes during production runs to assess any technical process issues and provides troubleshooting support as needed.
  • Author manufacturing investigations and complete CAPA assignments.
  • Composes process validation documentation, including CQA assessment, pFMEA risk assessment, and process validation protocols.
  • Identifies specific parameters, sampling, and tests used in the validation protocols of new and existing products.
  • Interact with clients during routinely scheduled project meetings.
  • Ensures timely completion and compliance with cGMP and all other relevant company training requirements.
  • Other duties as assigned.

  • Bachelor’s degree in Engineering, Pharmacy, or Chemistry.
  • 5 years of experience of technical support in a sterile pharmaceutical manufacturing environment.
  • Previous experience supporting tech transfer of parenteral Drug Products preferred.

  • Excellent verbal communication, written communication, documentation, negotiation, critical thinking, analytical, problem solving, detail orientation, organization and time management skills required.
  • Working knowledge of cGMP requirements related to sterile Drug Product manufacturing processes.
  • Working knowledge of EU regulations preferred.
  • Proficiency with Microsoft office (Word, Excel, Outlook) required.
  • Ability to interact with internal stakeholders and external customers.

  • Up to 5% domestic travel.

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is required to frequently stand, walk, sit; talk or hear; use hands to finger, handle or feel. The employee is required some of the time to reach with hands and arms. The employee is required occasionally to climb or balance; and taste or smell. The employee must frequently lift and/or move up to 25 pounds. There is no special vision requirement for this job. The employee may occasionally work near moving mechanical parts; fumes or airborne particles; toxic or caustic chemicals.

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