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Senior Clinical Data Manager Jobs (NOW HIRING)

AccuScan Sciences

Clinical Data Manager

Milpitas, CA · On-site

Position Summary The Clinical Data Manager (CDM) is responsible for the end-to-end management, quality control, and analysis of clinical cohort data. This role ensures data integrity, identifies and ...

AccuScan Sciences

Clinical Data Manager

Milpitas, CA

Position Summary The Clinical Data Manager (CDM) is responsible for the end-to-end management, quality control, and analysis of clinical cohort data. This role ensures data integrity, identifies and ...

ZS

Clinical Data Manager

Philadelphia, PA · On-site

... Manager to lead a high-velocity team focused on the future of Biometrics and Clinical Data. We are ... Bridge Strategy & Tech: Act as a hands-on liaison between senior stakeholders and engineering teams ...

Abbott

Clinical Data Manager

Maple Grove, MN · On-site

$45 - $47/hr

Clinical Data Manager Location: Maple Grove, MN Duration: 7 Months 100% Onsite Summary: The Clinical Data Manager is responsible for managing the development, documentation, and execution of risk ...

Collabera

Clinical Data Manager

Irvine, CA

Clinical Data Manager Location: Irvine, CA USA 92618 Duration: 12 months (Strong Possibility of Extension) Employment Type: W2 Contingent Worker SUMMARY OF POSITION: As a key member of the Global ...

IQVIA

Senior Data Team Lead (Remote)

Oakland, CA · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Atlanta, GA · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Dallas, TX · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Charleston, SC · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Austin, TX · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Chicago, IL · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Tampa, FL · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Charleston, WV · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Anaheim, CA · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Virginia Beach, VA · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Las Vegas, NV · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

IQVIA

Senior Data Team Lead (Remote)

Richmond, VA · Remote

$86K - $217K/yr

Lead data management for complex, global clinical trials from study setup to database lock. * Serve as the main client contact for all data management deliverables. * Oversee SAE, PK, and external ...

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Senior Clinical Data Manager information

See salary details

$79K

$123.1K

$184.5K

How much do senior clinical data manager jobs pay per year?

As of Aug 12, 2026, the average yearly pay for senior clinical data manager in the United States is $123,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $137,500.00 per year, depending on experience, location, and employer.

What does a senior clinical data manager do?

A Senior Clinical Data Manager oversees the collection, validation, and management of clinical trial data to ensure its accuracy, integrity, and compliance with regulatory standards. They design and implement data management plans, coordinate with clinical teams, monitor data quality, and resolve discrepancies. In addition, they may lead data management teams and play a key role in preparing data for statistical analysis and regulatory submissions. Their work is crucial for supporting clinical research and ensuring reliable study results.

What are the key skills and qualifications needed to thrive as a senior clinical data manager, and why are they important?

To thrive as a Senior Clinical Data Manager, you need a solid background in clinical research, data management practices, and a relevant degree such as life sciences or computer science. Familiarity with clinical data management systems (CDMS), electronic data capture (EDC) platforms, and knowledge of regulatory guidelines like GCP are essential, along with certifications such as CCDM. Strong leadership, analytical thinking, attention to detail, and excellent communication skills set top performers apart in this role. These skills ensure data integrity, regulatory compliance, and effective collaboration across cross-functional clinical teams, which are critical to the success of clinical trials.

How does a senior clinical data manager typically collaborate with cross-functional teams during a clinical trial?

As a Senior Clinical Data Manager, you will work closely with clinical operations, biostatistics, medical writers, and regulatory teams throughout the lifecycle of a clinical trial. Your responsibilities often include coordinating data collection processes, ensuring data integrity, and resolving discrepancies by communicating with site monitors and data entry staff. Regular meetings and updates are common to align on data review timelines, discuss protocol amendments, and address any data-related issues swiftly. This high level of collaboration helps ensure that the clinical trial runs smoothly and meets regulatory standards.

What is the difference between Senior Clinical Data Manager vs Clinical Data Coordinator?

AspectSenior Clinical Data ManagerClinical Data Coordinator
CredentialsBachelor's/Master's in Life Sciences, Biostatistics, or related field; experience in data managementBachelor's degree in Life Sciences or related field; entry-level experience
Work EnvironmentLeads data management teams, oversees data quality, and ensures complianceSupports data entry, validation, and basic data queries
Industry UsageUsed in pharmaceutical, biotech, and clinical research organizationsCommon in clinical trial sites and research organizations

The Senior Clinical Data Manager typically has more experience, oversees data management processes, and ensures data quality, while the Clinical Data Coordinator handles data entry and validation tasks. Both roles are essential in clinical research but differ in responsibility level and scope.

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Senior Clinical Data Manager jobs near you
Infographic showing various Senior Clinical Data Manager job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 12% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $123,055 per year, or $59.2 per hour.

Clinical Data Manager

AccuScan Sciences

Milpitas, CA • On-site

Full-time

Re-posted 3 days ago

Job description

Position Summary

The Clinical Data Manager (CDM) is responsible for the end-to-end management, quality control, and analysis of clinical cohort data. This role ensures data integrity, identifies and resolves irregularities, and partners closely with laboratory operations and bioinformatics engineering to enable high-quality and timely data delivery. The CDM will play a critical role in supporting clinical data pipelines, investigating anomalies, and driving MRD-focused analyses, pipeline improvements, and research initiatives.

Clinical Data Management & QC

• Manage and track clinical cohorts, ensuring accurate sample metadata and traceability

• Perform QC review, validation checks, and deviation logging across datasets

• Identify and investigate irregularities (e.g., contamination, sample swaps, unexpected results)

• Ensure reproducibility, traceability, and audit readiness of clinical datasets

Data Investigation & Pipeline Interaction

• Investigate abnormalities using statistical and bioinformatics approaches

• Run and monitor pipelines for data reprocessing and corrections

• Interface with bioinformatics pipelines via command line and scripting

• Troubleshoot data issues end-to-end from raw data through final outputs

Cross-Functional Collaboration

• Act as liaison between Lab Operations and Bioinformatics Engineering

• Ensure rapid resolution of data issues and timely delivery

• Communicate findings clearly and escalate issues when necessary

Data Systems & Reporting

• Interact with internal databases and correct inconsistencies

• Develop dashboards to monitor cohort progress, QC metrics, and delivery timelines

• Generate reports summarizing data quality, deviations, and investigations

Advanced Analysis & Research Support

• Perform in-depth analysis on unblinded clinical datasets

• Identify biological signals, artifacts, and noise sources (especially in MRD contexts)

• Drive improvements to pipelines and QC heuristics based on data insights

• Support development of new assays and analytical approaches

• Contribute to publications, internal reports, and regulatory documentation

Regulatory & External Collaboration

• Support documentation for regulatory submissions and audit readiness

• Prepare clinical datasets for collaborators

• Manage data transfer, submission, and tracking across studies

Requirements

Required Qualifications & Skills

• PhD in Bioinformatics, Computational Biology, Statistics, or related field

• 3–7+ years of experience in clinical data management or clinical genomics

• Strong experience with NGS data, including MRD (minimal residual disease) analysis

• Proficiency in Python (pandas or similar for data analysis)

• Experience with SQL or database systems

• Familiarity with Linux/Unix and command-line tools

• Strong statistical and analytical skills

• Ability to work cross-functionally in a fast-paced environment

Preferred

• Experience with tumor-normal and cfDNA workflows

• Experience building dashboards or tracking tools

• Knowledge of GCP and regulatory processes

• Experience supporting submissions and publications