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Senior Clinical Data Manager Jobs in Philadelphia, PA

Lead Clinical Data Manager (Remote)

Philadelphia, PA ยท Remote

$68.50K - $217.10K/yr

Your previous roles/job titles may include Clinical Data Manager, Senior Clinical Data Manager, Lead Data Manager, Principal Data Manager, and/or Data Management Project Manager . * Proven success ...

Lead Clinical Data Manager (Remote)

Philadelphia, PA ยท Remote

$68.50K - $217.10K/yr

Your previous roles/job titles may include Clinical Data Manager, Senior Clinical Data Manager, Lead Data Manager, Principal Data Manager, and/or Data Management Project Manager . * Proven success ...

Ability to manage (complete database tasks), track and oversee CRO responsibilities for overall performance management and provide updates to Head of Data Management. Senior Clinical Database ...

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Showing results 1-20

Senior Clinical Data Manager information

See Philadelphia, PA salary details

$75.5K

$117.6K

$176.3K

How much do senior clinical data manager jobs pay per year?

As of May 28, 2026, the average yearly pay for senior clinical data manager in Philadelphia, PA is $117,607.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,900.00 and $131,400.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Clinical Data Manager, and why are they important?

To thrive as a Senior Clinical Data Manager, you need a solid background in clinical research, data management practices, and a relevant degree such as life sciences or computer science. Familiarity with clinical data management systems (CDMS), electronic data capture (EDC) platforms, and knowledge of regulatory guidelines like GCP are essential, along with certifications such as CCDM. Strong leadership, analytical thinking, attention to detail, and excellent communication skills set top performers apart in this role. These skills ensure data integrity, regulatory compliance, and effective collaboration across cross-functional clinical teams, which are critical to the success of clinical trials.

How does a Senior Clinical Data Manager typically collaborate with cross-functional teams during a clinical trial?

As a Senior Clinical Data Manager, you will work closely with clinical operations, biostatistics, medical writers, and regulatory teams throughout the lifecycle of a clinical trial. Your responsibilities often include coordinating data collection processes, ensuring data integrity, and resolving discrepancies by communicating with site monitors and data entry staff. Regular meetings and updates are common to align on data review timelines, discuss protocol amendments, and address any data-related issues swiftly. This high level of collaboration helps ensure that the clinical trial runs smoothly and meets regulatory standards.

What does a Senior Clinical Data Manager do?

A Senior Clinical Data Manager oversees the collection, validation, and management of clinical trial data to ensure its accuracy, integrity, and compliance with regulatory standards. They design and implement data management plans, coordinate with clinical teams, monitor data quality, and resolve discrepancies. In addition, they may lead data management teams and play a key role in preparing data for statistical analysis and regulatory submissions. Their work is crucial for supporting clinical research and ensuring reliable study results.

What is the difference between Senior Clinical Data Manager vs Clinical Data Coordinator?

AspectSenior Clinical Data ManagerClinical Data Coordinator
CredentialsBachelor's/Master's in Life Sciences, Biostatistics, or related field; experience in data managementBachelor's degree in Life Sciences or related field; entry-level experience
Work EnvironmentLeads data management teams, oversees data quality, and ensures complianceSupports data entry, validation, and basic data queries
Industry UsageUsed in pharmaceutical, biotech, and clinical research organizationsCommon in clinical trial sites and research organizations

The Senior Clinical Data Manager typically has more experience, oversees data management processes, and ensures data quality, while the Clinical Data Coordinator handles data entry and validation tasks. Both roles are essential in clinical research but differ in responsibility level and scope.

What are the most commonly searched types of Senior Clinical Data jobs in Philadelphia, PA? The most popular types of Senior Clinical Data jobs in Philadelphia, PA are:
What are popular job titles related to Senior Clinical Data Manager jobs in Philadelphia, PA? For Senior Clinical Data Manager jobs in Philadelphia, PA, the most frequently searched job titles are:
What job categories do people searching Senior Clinical Data Manager jobs in Philadelphia, PA look for? The top searched job categories for Senior Clinical Data Manager jobs in Philadelphia, PA are:
Infographic showing various Senior Clinical Data Manager job openings in Philadelphia, PA as of May 2026, with employment types broken down into 1% As Needed, 83% Full Time, 13% Part Time, 1% Temporary, and 2% Contract. Highlights an 82% Physical, 2% Hybrid, and 16% Remote job distribution, with an average salary of $117,607 per year, or $56.5 per hour.
SR. CLINICAL DATA MANAGER

SR. CLINICAL DATA MANAGER

ACL Digital

King Of Prussia, PA โ€ข On-site

Full-time

This job post hasย expired today.ย Applications are no longer accepted.


Job description

DUTIES:
โ€ข Serve as the DM study lead and the primary point of contact for clinical study teams and external partners, (e.g., external data vendors and CROs) for multiple trials within a given TA.
โ€ข Lead all aspects of all DM activities across all stages of the trial from study start-up through archiving. Accountable for providing comprehensive program level oversight of SDMs to ensure consistency and compliance of program level standards, track milestones/deliverables, escalate and follow to resolution and communicate program level updates to SDMs
โ€ข Provide clear verbal or written information and hands-on support to project team members and to CROs related to eCRF and database design, data quality, and reporting of database / data quality status.
โ€ข Interact cross-functionally and provide project leadership for SDMs within the program
โ€ข Collaborate with data management peers and other cross functional stakeholders to define and develop operational type of reports to assist with data exploration and metrics.
โ€ข Perform & document the oversight of CRO data management activities for assigned studies.
โ€ข Data Management Plan (includes: Data Review, Reconciliation and Cleaning, Coding, SAE Recon, Local Lab Handling activities for CRF and non-CRF data
โ€ข Lead data transfers with CROs and third-party data sources, SAE/AE reconciliation and MedDRA /WHO-DD coding. โ€ข Support the transfer, locking, and archiving of study databases. Lead scheduling and time constrains across multiple projects.
โ€ข Prepare recommendations for new or improved processes for data management and data flow. โ€ข Ensure the eTMF documentation is maintained on a regular basis for assigned studies
โ€ข Perform quality review and inspection readiness tasks to meet quarterly Inspection Readiness Review (IRR) compliance
โ€ข Own the implementation and execution of procedures for data quality review and data acceptance prior to data analyses and/or database lock.
โ€ข Ensure and manage clinical data are processed according to Good Clinical Practices (GCP), Standard Operating Procedures (SOPs) and Data Handling Guidelines
REQUIREMENTS:
  • Master's degree Health Administration, Pharmacy or related discipline
  • 24 months experience
  • Must also have experience with at least one of the following areas/technologies also required: ECS, TMF, CCG, UAT, CRF Specification, QC, DTA/DT
Email resume to: hr.us@acldigital.com

ACL Digital logo

About ACL Digital

Sourced by ZipRecruiter

ACL Digital is a global digital technology firm based in San Jose, CA, US, operating within the IT and services industry. The company offers a broad spectrum of services and solutions, including digital transformation, product engineering, industry solutions, and design-led experiences, among others. ACL Digital has its roots established in 1991 with the aim to become a leading-edge innovator in the digital space and has since grown significantly to work with an array of global customers. The company's mission incorporates a commitment to aiding customers to achieve their business goals by adopting and accelerating their digital transformation journeys.

Industry

Technology, communication and media

Company size

1,001 - 5,000 Employees

Headquarters location

San Jose, CA, US

Year founded

1992