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Clinical Project Manager - Oncology (Client Dedicated/Remote)

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture - where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives - we're able to create a place where everyone feels like they belong.

Job Responsibilities

CLINICAL PROJECT MANAGER II - ONCOLOGYSponsor Dedicated | Remote - United States

Are you passionate about advancing cancer research and bringing innovative therapies to patients worldwide? We are seeking experienced Clinical Project Managers with strong global oncology clinical trial experience to join a high-performing sponsor-dedicated team supporting a diverse portfolio of oncology studies across multiple indications and phases of development.

This is a fully remote, US-based opportunity, with up to 25% travel, where you will play a critical role in the operational leadership and execution of global clinical trials. We are specifically seeking professionals with 3+ years of hands-on Clinical Project Management experience leading global oncology studies and collaborating with cross-functional teams, vendors, and international stakeholders.

WHAT YOU'LL DO

As a Clinical Project Manager II, you will help drive the operational execution and delivery of global oncology clinical trials, ensuring studies are conducted efficiently, compliantly, and according to established timelines.

Key Responsibilities

• Support and partner with Clinical Study Leads and cross-functional study teams on global oncology trials

• Lead day-to-day study management activities across study startup, conduct, maintenance, and closeout

• Manage study timelines, deliverables, risks, and issue resolution

• Oversee external vendors, CROs, central laboratories, imaging vendors, and specialty providers

• Coordinate Clinical Trial Team (CTT) meetings and drive action item follow-up

• Support study-level planning, forecasting, and operational strategy execution

• Monitor study performance metrics and proactively identify areas requiring intervention

• Ensure inspection readiness and compliance with applicable regulations and sponsor requirements

• Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality

• Contribute to study status reporting and executive-level communications

• Support achievement of study milestones, enrollment targets, database locks, and study closeout activities

• Travel up to 25%

WHAT YOU WILL BRINGRequired Qualifications

• Bachelor's degree in a scientific, healthcare, or related field is required

• 3+ years of Clinical Project Management experience supporting global oncology clinical trials

• Experience managing studies across multiple countries and regions (North America, Europe, Asia-Pacific, Latin America, or other global regions)

• Vendor management experience required

• Strong understanding of clinical trial operations and study lifecycle management

• Experience supporting Phase I, Phase II, Phase III, and/or Phase IV oncology studies

• Strong working knowledge of ICH-GCP guidelines and clinical research regulations

• Proficiency with Microsoft Office Suite

• Ability to work effectively within global, cross-functional matrix organizations

ONCOLOGY THERAPEUTIC AREA EXPERIENCE

Candidates should have direct clinical trial experience supporting one or more oncology indications:

• Lung cancer (NSCLC, SCLC)

• Melanoma

• Renal cell carcinoma (kidney)

• Bladder cancer

• Head & neck squamous cell carcinoma

• Triple-negative breast cancer

• Cervical cancer

• Gastric and gastroesophageal cancers

• Esophageal cancer

• Hepatocellular carcinoma (liver)

• Endometrial cancer

• Ovarian cancer

• Colorectal cancer

• Biliary tract cancer

• Prostate cancer

• Urothelial carcinoma

• Hematologic malignancies (multiple myeloma, lymphoma, leukemia)

• Antibody-drug conjugates (ADCs)

• Personalized cancer vaccines

• KRAS inhibitors

• T-cell engagers

• Cell-directed immunotherapies

Candidates should be prepared to discuss the indications supported, study phases, geographic scope, and their specific responsibilities on each program.

PREFERRED QUALIFICATIONS

• Experience independently leading global oncology studies

• Experience supporting complex, multi-regional Phase II and Phase III programs

• Experience with early-phase oncology studies (Phase I/Ib)

• Experience with immuno-oncology, targeted therapies, cell therapy, or hematologic malignancies

• Familiarity with CTMS, eTMF, IRT/RTSM, and clinical data review platforms

• Experience working in sponsor-dedicated or FSP environments

KEY SKILLS & COMPETENCIES

• Strong project management and organizational skills

• Excellent communication and stakeholder management abilities

• Proven ability to manage multiple priorities in a fast-paced environment

• Strong risk identification and mitigation capabilities

• Detail-oriented with a focus on quality, compliance, and execution

• Strong collaboration skills across global teams and functions

• Ability to influence without direct authority and drive accountability across study teams

CLINICAL PHASE EXPERIENCE

We welcome candidates with experience supporting:

• Phase I / First-in-Human Studies

• Phase I/Ib Dose Escalation Studies

• Phase II Proof-of-Concept Studies

• Phase II/III Registrational Studies

• Phase III Global Pivotal Trials

• Phase IV and Post-Marketing Studies

Experience supporting global, multi-country oncology programs through multiple phases of development is highly preferred.

WHY JOIN US?

• Work on innovative oncology programs advancing new treatment options for cancer patients worldwide

• Support cutting-edge therapies across solid tumors, hematologic malignancies, immuno-oncology, and cell and gene therapy

• Join a collaborative, sponsor-dedicated team focused on operational excellence

• Enjoy the flexibility of a fully remote US-based role

• Expand your impact across global clinical development programs and contribute to bringing life-changing therapies to patients

If you are an experienced Oncology Clinical Project Manager with 3+ years of global clinical trial management experience and a passion for advancing cancer research, we would love to hear from you.

Salary Range $120,000-135,000

We are always excited to connect with great talent. This posting is intended for a [possible] upcoming opportunity rather than a live role. By expressing your interest, you'll be added to our talent pipeline and considered should this role become available.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.