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Remote Principal Scientist Jobs (NOW HIRING)

As our Principal Applied Scientist, you will play a key role in shaping the future of AI at Oracle, with an emphasis on Large Language Models (LLMs) and Generative AI. Your contributions will be ...

As our Principal Applied Scientist, you will play a key role in shaping the future of AI at Oracle, with an emphasis on Large Language Models (LLMs) and Generative AI. Your contributions will be ...

Position Overview We are seeking an experienced and hands-on Principal Scientist, ADME/PK to lead ... We are a remote-first company, with occasional travel for in-person team meetings or scientific ...

About the Principal Data Scientist at Headspace: We are looking for an innovative, strategic and ... City, NY (remote), and Seattle, WA (remote). Candidates must permanently reside in the US ...

Over 750 teammates are dispersed throughout Boston, Raleigh, New York, Lisbon, Singapore, and remote We are hiring a visionary Principal Data Scientist in a critical senior technical leadership role ...

We collaborate closely with platform, product, and operations partners in a fast-moving, remote ... About the role As a Principal Applied Scientist focused on RL post-training, you will lead the ...

Posting Type Remote/Hybrid Job Overview WHO WE ARE Relativity is a leading legal data intelligence ... As a Principal Applied Scientist, Reliability, you will lead the design and validation of ...

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Remote Principal Scientist information

See salary details

$68.5K

$144K

$190.5K

How much do remote principal scientist jobs pay per year?

As of Jun 9, 2026, the average yearly pay for remote principal scientist in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What is the difference between Remote Principal Scientist vs Remote Senior Scientist?

AspectRemote Principal ScientistRemote Senior Scientist
CredentialsAdvanced degree (PhD or equivalent), extensive research experienceMaster's or PhD, significant research background
Work EnvironmentLeads research projects, strategic planning, cross-functional collaborationConducts experiments, data analysis, supports project goals
Industry UsageUsed in biotech, pharma, and research-focused companiesCommon in similar industries, often as a senior technical role

The Remote Principal Scientist typically holds a higher level of responsibility, leading research initiatives and strategic decisions, whereas the Remote Senior Scientist focuses more on executing research tasks and supporting project development. Both roles require advanced scientific credentials and are prevalent in research-intensive industries, but the Principal Scientist has a broader leadership scope.

What does a Remote Principal Scientist do?

A Remote Principal Scientist leads scientific research and development projects from a remote location, often overseeing teams, designing experiments, analyzing data, and providing expert guidance. They are responsible for setting research goals, ensuring scientific integrity, and contributing to strategic decisions in their field. Working remotely, they use digital tools to collaborate with colleagues, present findings, and manage project timelines. Their expertise often influences company policies, product development, or scientific direction.

How does a Remote Principal Scientist effectively collaborate with cross-functional teams while working offsite?

As a Remote Principal Scientist, effective collaboration often relies on leveraging digital communication tools and maintaining proactive engagement with cross-functional teams. Regular virtual meetings, clear documentation, and timely feedback are key to ensuring alignment on project goals and scientific direction. Building strong relationships with team members across research, regulatory, and product development functions helps streamline decision-making and problem-solving, even when working remotely. Adapting to different time zones and communication styles can be a common challenge, but flexibility and strong organizational skills are essential for maintaining productivity and team cohesion.

What are the key skills and qualifications needed to thrive as a Remote Principal Scientist, and why are they important?

To thrive as a Remote Principal Scientist, you need deep expertise in your scientific discipline, a PhD or equivalent experience, and a track record of leading successful research projects. Proficiency with advanced data analysis tools, laboratory information management systems (LIMS), and collaboration platforms is typically required. Strong leadership, communication, and self-motivation are essential soft skills, especially for managing remote teams and cross-functional projects. These skills ensure effective research direction, innovative problem-solving, and successful collaboration in a virtual scientific environment.
More about Remote Principal Scientist jobs
What cities are hiring for Remote Principal Scientist jobs? Cities with the most Remote Principal Scientist job openings:
What are the most commonly searched types of Principal Scientist jobs? The most popular types of Principal Scientist jobs are:
What states have the most Remote Principal Scientist jobs? States with the most job openings for Remote Principal Scientist jobs include:
What job categories do people searching Remote Principal Scientist jobs look for? The top searched job categories for Remote Principal Scientist jobs are:
Infographic showing various Remote Principal Scientist job openings in the United States as of May 2026, with employment types broken down into 1% Internship, 31% Full Time, 64% Part Time, 2% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $144,009 per year, or $69.2 per hour.
[Remote] Principal Applied Scientist

[Remote] Principal Applied Scientist

Oracle

Remote

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 17 days ago


Oracle rating

8.7

Company rating: 8.7 out of 10

Based on 133 frontline employees who took The Breakroom Quiz

38th of 186 rated software companies


Job description

Job Description
Building off our Cloud momentum, Oracle has formed a new organization - Oracle Health & AI. This team will focus on product development and product strategy for Oracle Health, while building out a complete platform supporting modernized, automated healthcare. This is a net new line of business, constructed with an entrepreneurial spirit that promotes an energetic and creative environment. We are unencumbered and will need your contribution to make it a world class engineering center with the focus on excellence.
As our Principal Applied Scientist, you will play a key role in shaping the future of AI at Oracle, with an emphasis on Large Language Models (LLMs) and Generative AI. Your contributions will be pivotal in delivering our new Generative AI-powered solutions for healthcare and enterprise customers.
Responsibilities
  • Collaborate with product managers to translate business and product requirements into AI projects.
  • Collaborate with fellow technical leaders to ensure the successful and timely delivery of models and integration of services.
  • Coordinate with multinational teams to drive projects from research POC to production.
  • Develop new healthcare and enterprise services and features leveraging recent advances in generative AI, machine learning and deep learning.
  • Design and review the architecture of AI solutions, including data, model, training, and evaluation, employing best practices.
  • Lead and mentor both junior and senior applied scientists.
  • Develop production code and advocate for the best coding and engineering practices.
  • Participate in project planning, review, and retrospective sessions.
  • Identify and mitigate risks in our plans and executions, especially at the intersection of business and engineering.

Qualifications and Experience
  • Demonstrated experience in designing and implementing scalable AI models for production.
  • Deep technical understanding of Machine Learning, Deep Learning architectures like Transformers, training methods, and optimizers.
  • Practical experience with the latest technologies in LLM and generative AI, such as parameter-efficient fine-tuning, instruction fine-tuning, and advanced prompt engineering techniques like Tree-of-Thoughts.
  • Hands-on experience with emerging LLM frameworks and plugins, such as LangChain, LlamaIndex, VectorStores and Retrievers, LLM Cache, LLMOps (MLFlow), LMQL, Guidance, etc.
  • Proven experience in designing data collection/annotation solutions and systematic evaluation necessary for developing and maintaining production systems.
  • Commitment to staying up-to-date with the field and applying academic advances to solve complex business problems, and bringing them into production.
  • Strong publication record, including as a lead author or reviewer, in top-tier journals or conferences.
  • Experienced leading senior scientists and early-career scientists.

Preferred Qualifications
  • Knowledge of healthcare and experience delivering healthcare AI models are a significant plus.
  • Familiarity and experience with the latest advancements in computer vision and multimodal modeling is a plus.

Education
  • PhD Computer Science, Mathematics, Statistics, Physics, Linguistics or a related field with a dissertation, thesis or final project centered in Machine Learning and Deep Learning) with 3+ years relevant experience is preferred but not a must; OR
  • Masters or Bachelor's in related field with 5+ years relevant experience

Oracle is committed to incorporating generative AI into our applications and workflows for business users. This role presents a unique opportunity to work on pioneering AI technologies and contribute to Oracle's Generative AI strategy. At Oracle, we value diversity and encourage continuous learning for career growth. Come join our team to make a significant difference!
Qualifications
Disclaimer:
Certain U.S. based or U.S. customer or client-facing roles may be required to comply with applicable requirements, such as immunization/occupational health mandates, and/or drug testing requirements.
Range and benefit information provided in this posting are specific to the stated locations only
US: Hiring Range in USD from: $120,100 to $251,600 per annum. May be eligible for bonus, equity, and compensation deferral.
Oracle maintains broad salary ranges for its roles in order to account for variations in knowledge, skills, experience, market conditions and locations, as well as reflect Oracle's differing products, industries and lines of business.
Candidates are typically placed into the range based on the preceding factors as well as internal peer equity.
Oracle US offers a comprehensive benefits package which includes the following:
1. Medical, dental, and vision insurance, including expert medical opinion
2. Short term disability and long term disability
3. Life insurance and AD&D
4. Supplemental life insurance (Employee/Spouse/Child)
5. Health care and dependent care Flexible Spending Accounts
6. Pre-tax commuter and parking benefits
7. 401(k) Savings and Investment Plan with company match
8. Paid time off: Flexible Vacation is provided to all eligible employees assigned to a salaried (non-overtime eligible) position. Accrued Vacation is provided to all other employees eligible for vacation benefits. For employees working at least 35 hours per week, the vacation accrual rate is 13 days annually for the first three years of employment and 18 days annually for subsequent years of employment. Vacation accrual is prorated for employees working between 20 and 34 hours per week. Employees working fewer than 20 hours per week are not eligible for vacation.
9. 11 paid holidays
10. Paid sick leave: 72 hours of paid sick leave upon date of hire. Refreshes each calendar year. Unused balance will carry over each year up to a maximum cap of 112 hours.
11. Paid parental leave
12. Adoption assistance
13. Employee Stock Purchase Plan
14. Financial planning and group legal
15. Voluntary benefits including auto, homeowner and pet insurance
The role will generally accept applications for at least three calendar days from the posting date or as long as the job remains posted.
Career Level - IC4
About Us
Only Oracle brings together the data, infrastructure, applications, and expertise to power everything from industry innovations to life-saving care. And with AI embedded across our products and services, we help customers turn that promise into a better future for all. Discover your potential at a company leading the way in AI and cloud solutions that impact billions of lives.
True innovation starts when everyone is empowered to contribute. That's why we're committed to growing a workforce that promotes opportunities for all with competitive benefits that support our people with flexible medical, life insurance, and retirement options. We also encourage employees to give back to their communities through our volunteer programs.
We're committed to including people with disabilities at all stages of the employment process. If you require accessibility assistance or accommodation for a disability at any point, let us know by emailing accommodation-request_mb@oracle.com or by calling 1-888-404-2494 in the United States.
Oracle is an Equal Employment Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability and protected veterans' status, or any other characteristic protected by law. Oracle will consider for employment qualified applicants with arrest and conviction records pursuant to applicable law.

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About Oracle

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An Oracle career can span industries, roles, Countries and cultures, giving you the opportunity to flourish in new roles and innovate, while blending work life in. Oracle has thrived through 40+ years of change by innovating and operating with integrity while delivering for the top companies in almost every industry. In order to nurture the talent that makes this happen, we are committed to an inclusive culture that celebrates and values diverse insights and perspectives, a workforce that inspires thought leadership and innovation. Oracle offers a highly competitive suite of Employee Benefits designed on the principles of parity, consistency, and affordability. The overall package includes certain core elements such as Medical, Life Insurance, access to Retirement Planning, and much more. We also encourage our employees to engage in the culture of giving back to the communities where we live and do business. At Oracle, we believe that innovation starts with diversity and inclusion and to create the future we need talent from various backgrounds, perspectives, and abilities. We ensure that individuals with disabilities are provided reasonable accommodation to successfully participate in the job application, interview process, and in potential roles. to perform crucial job functions. That's why we're committed to creating a workforce where all individuals can do their best work. It's when everyone's voice is heard and valued that we're inspired to go beyond what's been done before.

Industry

It services

Company size

10,000+ Employees

Headquarters location

Redwood City, CA, US

Year founded

1977

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