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Senior Principal Scientist Jobs (NOW HIRING)

Apex Companies

Sr Principal Scientist

Austin, TX · On-site

Your Responsibilities as a Scientist 7 - Sr Principal Scientist: * Serve as senior technical lead on cumulative project total >$2.5M annually. * Contribute to successful business development of >$1M ...

Ardent Mills

Sr. Principal Scientist

Denver, CO · On-site

Join Us Today The Sr. Principal Scientist serves as a scientific leader and recognized subject matter expert in grain science, flour functionality, baking applications, ingredient technology, and ...

Ardent Mills

Sr. Principal Scientist

Denver, CO · On-site

$145 - $170/hr

The Sr. Principal Scientist serves as a scientific leader and recognized subject matter expert in grain science, flour functionality, baking applications, ingredient technology, and food innovation.

Ardent Mills

Sr. Principal Scientist

Denver, CO · On-site

The Sr. Principal Scientist serves as a scientific leader and recognized subject matter expert in grain science, flour functionality, baking applications, ingredient technology, and food innovation.

Ardent Mills

Sr. Principal Scientist

Denver, CO

The Sr. Principal Scientist serves as a scientific leader and recognized subject matter expert in grain science, flour functionality, baking applications, ingredient technology, and food innovation.

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Senior Principal Scientist information

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$68.5K

$144K

$190.5K

How much do senior principal scientist jobs pay per year?

As of Aug 24, 2026, the average yearly pay for senior principal scientist in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What is a senior principal scientist?

A Senior Principal Scientist is an advanced-level research professional who leads complex scientific projects and provides strategic direction within their field of expertise. They typically oversee teams of scientists, develop research programs, and contribute to the advancement of scientific knowledge or product innovation. This role often requires extensive experience, a doctoral degree, and a proven track record of impactful research. Senior Principal Scientists also mentor junior staff and collaborate with cross-functional teams to achieve organizational goals.

What does a senior principal scientist do?

As a Senior Principal Scientist, you will often serve as a scientific leader and subject matter expert on cross-functional project teams, working closely with colleagues in research, development, regulatory, and commercial departments. Your responsibilities may include designing experiments, interpreting complex data, and providing strategic input to guide project direction. Effective collaboration and communication are key, as you will mentor junior scientists, align research goals with business objectives, and ensure scientific rigor across projects. This role often involves presenting findings to both technical and non-technical stakeholders, requiring the ability to translate complex science into actionable recommendations.

What skills and qualifications are needed to be a senior principal scientist?

To thrive as a Senior Principal Scientist, you need an advanced degree (PhD) in a relevant scientific field, extensive research experience, and a strong track record of publications and project leadership. Familiarity with specialized laboratory equipment, data analysis software, and regulatory compliance systems is typically required. Exceptional problem-solving, mentorship, and collaboration skills help distinguish top performers in this position. These qualifications are crucial for driving scientific innovation, ensuring research quality, and leading multidisciplinary teams to achieve impactful results.

What is the difference between Senior Principal Scientist vs Principal Scientist?

AspectSenior Principal ScientistPrincipal Scientist
Required CredentialsAdvanced degrees (PhD), extensive research experience, industry certificationsMaster's or PhD, significant research background
Work EnvironmentLeading complex projects, mentoring teams, strategic planningConducting research, developing new methods, supporting project teams
Employer & Industry UsageResearch institutions, biotech, pharma, tech companiesResearch labs, R&D departments in similar industries

Senior Principal Scientists typically hold more advanced credentials and lead strategic initiatives, mentoring teams and overseeing large projects. Principal Scientists focus on conducting research and developing innovations, often supporting senior staff. Both roles are vital in R&D, but the Senior Principal Scientist has a broader leadership and strategic scope.

What is the average salary for a Senior Principal Scientist?

The average salary for a Senior Principal Scientist in the US typically ranges from $130,000 to $180,000 annually, depending on industry, location, and experience. Senior Principal Scientists often hold advanced degrees and have extensive expertise in their field, which can influence compensation levels.
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Cities with the most Senior Principal Scientist job openings:

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Senior Principal Scientist jobs near you
Infographic showing various Senior Principal Scientist job openings in the United States as of August 2026, with employment types broken down into 89% Full Time, 9% Part Time, 1% Temporary, and 1% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $144,009 per year, or $69.2 per hour.

Sr Principal Scientist

Apex Companies

Austin, TX • On-site

Full-time

Medical, Dental, Life, Retirement

Posted 18 days ago

Job description

Your Responsibilities as a Scientist 7 - Sr Principal Scientist:

  • Serve as senior technical lead on cumulative project total >$2.5M annually.
  • Contribute to successful business development of >$1M annually.
  • Write and review technical reports and proposals.
  • Prepare and deliver marketing presentations.
  • Assist with project management activities.
  • Mentor and train scientific staff and ensure quality work product.

What we're looking for:

  • BS in related scientific field, Master's preferred.
  • Professional accreditation. 
  • 15+ years of experience with environmental services including technical writing and providing technical oversight.
  • Business development.
  • Project Management.
  • Ability to mentor and train staff.
  • Strong technical writing skills, the ability to successfully multi-task, safety awareness, and a good record and understanding of safe work practices.
  • Microsoft 365 / CRM
  • Valid driver's license, good driving history and reliable transportation are required.

Why you'll love working for us:

  • Company-subsidized medical and dental.
  • Company-paid life, short, and long-term disability.
  • 401k match, tuition assistance, and more.
  • Cross-training and the ability to work on a variety of projects.
  • Performance-based bonuses or other incentives.
  • Working with the best and brightest in the industry.
  • 2,000+ employee national firm with 70+ locations across the US.

#LI-MW1

Apex Job Title: Scientist 7 - Sr Principal Scientist

Req ID: 11921

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