1

Registered Nurse Informatics Jobs (NOW HIRING)

RN Informatics Specialist - MCHS

Eau Claire, WI · On-site

$85.47K - $128.25K/yr

... informatics. Assists with the communication between Mayo Clinic Health System, Mayo Health System ... Understands clinical end user and registered nurse job responsibilities and analyzes impact on work ...

Licenses and Certifications (RN) REGISTERED NURSE Upon Hire Preferred * Education Master's Degree in Nursing, Nursing Informatics or Healthcare Business (MBA or MHA) preferred. * Licenses and ...

next page

Showing results 1-20

Registered Nurse Informatics information

See salary details

$42.5K

$98.4K

$166.5K

How much do registered nurse informatics jobs pay per year?

As of Jun 1, 2026, the average yearly pay for registered nurse informatics in the United States is $98,409.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $122,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Registered Nurse Informatics, and why are they important?

To thrive as a Registered Nurse Informatics, you need a strong clinical background as a registered nurse combined with specialized knowledge in health informatics, often supported by a BSN and certifications like the ANCC Nursing Informatics certification. Proficiency with electronic health records (EHRs), data analysis tools, and healthcare information systems is crucial. Excellent communication, problem-solving, and project management skills help bridge the gap between clinical staff and IT teams. These competencies ensure effective implementation and optimization of technology to improve patient care and streamline healthcare processes.

How does a Registered Nurse Informatics professional typically collaborate with clinical and IT teams to implement new healthcare technologies?

Registered Nurse Informatics professionals act as a bridge between clinical staff and IT teams, ensuring that new healthcare technologies meet the needs of both users and patients. They gather feedback from nurses and other clinicians, translate clinical requirements into technical specifications, and assist in configuring or customizing clinical information systems. Collaboration often involves leading training sessions, participating in interdisciplinary meetings, and troubleshooting issues to optimize system performance. This teamwork is essential for successful technology adoption and improving patient care outcomes.

What is a Registered Nurse Informatics?

A Registered Nurse Informatics (RN Informatics) is a licensed nurse who specializes in integrating nursing science with information management and analytical sciences to improve healthcare outcomes. They work at the intersection of nursing, computer science, and information technology, helping to design, implement, and optimize electronic health records (EHR) and other digital healthcare systems. RN Informatics professionals also train staff, analyze data for quality improvement, and ensure technology meets clinical needs. Their work helps streamline workflows, enhance patient safety, and improve the quality of care.

What is the difference between Registered Nurse Informatics vs Registered Nurse?

AspectRegistered Nurse InformaticsRegistered Nurse
CredentialsRN license, possibly additional certifications in informatics or health ITRN license, basic nursing certifications
Work EnvironmentHospitals, clinics, healthcare IT companies, electronic health record (EHR) systemsHospitals, clinics, long-term care facilities
Job FocusIntegrating technology into patient care, data management, system optimizationDirect patient care, clinical procedures, patient education

Registered Nurse Informatics professionals specialize in combining nursing expertise with health IT to improve patient outcomes and streamline healthcare processes. In contrast, Registered Nurses focus primarily on direct patient care. While both roles require RN licensure, informatics nurses often have additional certifications and work more with technology and data systems. Understanding these differences helps healthcare organizations and job seekers identify the right career path or job opportunity.

More about Registered Nurse Informatics jobs
What cities are hiring for Registered Nurse Informatics jobs? Cities with the most Registered Nurse Informatics job openings:
What states have the most Registered Nurse Informatics jobs? States with the most job openings for Registered Nurse Informatics jobs include:
Infographic showing various Registered Nurse Informatics job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $98,409 per year, or $47.3 per hour.
RN Informatics Specialist - MCHS

RN Informatics Specialist - MCHS

Mayo Clinic

Eau Claire, WI • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 10 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 673 frontline employees who took The Breakroom Quiz

131st of 864 rated healthcare providers


Job description

This position will support Mayo Clinic Health System Department of Nursing with expectation to collaborate across the Enterprise, as appropriate.

Provides clinical information system leadership, assists with the implementation of system upgrades and enhancements. Participates in the development and pursuance of the organization's vision and strategic plan related to clinical informatics. Assists with the communication between Mayo Clinic Health System, Mayo Health System and Electronic Medical Record (EMR) vendor. Facilitates communication of functionality and process adoption procedures in a complex clinical environment. Understands clinical end user and registered nurse job responsibilities and analyzes impact on work flows in hospital settings.

This role is eligible for TN sponsorship. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Graduate of a nursing program.
All entry-level associate degree registered nurses with a RN start date of April 1, 2020 and after must provide documented evidence of program completion of a baccalaureate degree in nursing program within five years from the last day of the month of the RN start date. 
All entry-level associate degree registered nurses with a RN start date prior to April 1, 2020 must provide documented evidence of program completion of a baccalaureate degree in nursing program as stipulated by the degree requirement program in place at time of hire. 
5 years experience in clinical nursing practice. 

Ability to read and communicate effectively in English. Proficient computer skills (Microsoft office applications). Demonstrates skills in leadership, problem solving, continuous improvement, verbal and written communication, and team building. Excellent organization, time management and project planning skills. BSN or MSN preferred. Experience in the management and development of clinical information systems, preferred. Experience with Cerner health care solutions, preferred. 

License or certification:

Active Wisconsin RN License or ability to practice professional nursing in the state of Wisconsin.


What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Mayo Clinic logo

About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919