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Process Improvement Manager Jobs in Columbia, SC

Continuous Improvement Engineer

Gaston, SC · On-site

$75K - $100K/yr

... Management System (WMS) adoption and process compliance • Develop SOPs, training materials, and process documentation • Lead root cause analysis and corrective action efforts • Support change ...

The role requires an understanding of ETO systems and processes including Bid Manager, MI Manager ... Lead projects related to improvement and development of Product Line Systems and ETO tools while ...

The role requires an understanding of ETO systems and processes including Bid Manager, MI Manager ... Lead projects related to improvement and development of Product Line Systems and ETO tools while ...

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Process Improvement Manager information

See Columbia, SC salary details

$37.2K

$84K

$122.5K

How much do process improvement manager jobs pay per year?

As of Sep 7, 2026, the average yearly pay for process improvement manager in Columbia, SC is $84,046.00, according to ZipRecruiter salary data. Most workers in this role earn between $67,000.00 and $99,200.00 per year, depending on experience, location, and employer.

What is a process improvement manager?

A process improvement manager oversees the daily operations of a business or organization and suggests ways to improve efficiency and productivity. As a process improvement manager, you use software systems and other tools to collect data about processes. You analyze the information, identify areas that need improvement, and develop more efficient production systems. Qualifications to become a process improvement manager include several years of experience in the industry, especially in leadership roles.

What does a process improvement manager do?

A Process Improvement Manager is responsible for analyzing business processes and identifying areas where efficiency, quality, or productivity can be improved. They use methodologies like Lean, Six Sigma, or Kaizen to streamline workflows, reduce waste, and enhance customer satisfaction. Their role often involves leading cross-functional teams, implementing best practices, and measuring the impact of improvements. Ultimately, they help organizations save time and resources while delivering better results.

What are the key skills and qualifications needed to thrive as a process improvement manager, and why are they important?

To thrive as a Process Improvement Manager, you need expertise in process analysis, project management, and a strong background in business or engineering, often supported by a bachelor’s degree and certifications like Six Sigma or Lean. Familiarity with process mapping tools, data analysis software, and continuous improvement methodologies is typically required. Exceptional problem-solving, communication, and leadership skills help drive change and foster cross-functional collaboration. These capabilities are crucial for identifying inefficiencies, implementing sustainable improvements, and achieving organizational goals.

What are some common challenges process improvement managers face when implementing new initiatives, and how can they be addressed?

Process Improvement Managers often encounter resistance to change from employees who are accustomed to established workflows. Gaining buy-in from stakeholders and ensuring clear communication across departments are critical for successful implementation. To address these challenges, it's important to involve team members early in the process, provide training, and highlight the benefits of proposed improvements. Regular feedback sessions and transparent progress updates also help foster collaboration and minimize pushback.

What is the difference between Process Improvement Manager vs Business Analyst?

AspectProcess Improvement ManagerBusiness Analyst
Required CredentialsBachelor's degree; certifications like Six Sigma or LeanBachelor's degree; certifications like CBAP or PMI-PBA
Work EnvironmentLeads process optimization projects across departmentsAnalyzes business needs and recommends solutions
Employer & Industry UsageManufacturing, healthcare, finance, and techIT, finance, consulting, and corporate sectors

The Process Improvement Manager focuses on optimizing processes and implementing efficiency strategies, often leading cross-functional teams. In contrast, a Business Analyst primarily analyzes business requirements and recommends solutions to improve operations. While both roles require analytical skills and certifications like Six Sigma, their core responsibilities and work environments differ, making each role unique in organizational impact.

More about Process Improvement Manager jobs

What are the most commonly searched types of Process Improvement jobs in Columbia, SC?

The most popular types of Process Improvement jobs in Columbia, SC are:

What job categories do people searching Process Improvement Manager jobs in Columbia, SC look for?

The top searched job categories for Process Improvement Manager jobs in Columbia, SC are:

What cities near Columbia, SC are hiring for Process Improvement Manager jobs?

Cities near Columbia, SC with the most Process Improvement Manager job openings:

Infographic showing various Process Improvement Manager job openings in Columbia, SC as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 17% Part Time, 3% Contract, and 1% Nights. Highlights an 89% Physical, 2% Hybrid, and 9% Remote job distribution, with an average salary of $84,046 per year, or $40.4 per hour.

Change Control, Continuous Improvement Manager

NEPHRON SC, LLC

West Columbia, SC

Full-time

Re-posted 3 days ago


Job description

Description

Job Purpose:

The Change Control Continuous Improvement Manager is responsible for identifying, developing, and implementing process improvement initiatives within the Change Control and Document Revision functions. This role serves as a subject matter expert (SME) and internal lead for optimizing document lifecycle management, change control workflows, and electronic quality management system (eQMS) performance.  

Essential Duties and Responsibilities:

1. Continuous Improvement - Change Control and Document Revision
  • Lead continuous improvement efforts for change management processes, including initiation, impact assessment, approval routing, implementation, and closure. 
  • Analyze data to identify bottlenecks, recurring delays, incomplete submissions, and compliance risks. 
  • Establish and monitor key performance indicators (KPIs) for change control and document revision cycle time, on-time closure rates, and rejection rates. 
  • Collaborate with cross-functional stakeholders (Manufacturing, Engineering, Regulatory Affairs, Validation, and Quality) to ensure change control requirements are clearly understood and consistently applied. 
  • Conduct root cause analysis on change control deficiencies and implement corrective process improvements. 
2. eQMS System Optimization & Data Analysis
  • Serve as a functional lead and SME for the eQMS (Dot Compliance) as it relates to document control and change control modules. 
  • Generate and analyze quality system reports and dashboards to support management review, audit readiness, and performance trending. 
  • Identify and drive system configuration improvements to enhance workflow automation, routing efficiency, and compliance controls. 
  • Develop and maintain eQMS user training materials and deliver training to document control and change control end users.
3. Training & Change Management
  • Develop and deliver training programs on document control and change control processes, tools, and regulatory expectations. 
  • Champion a culture of quality and continuous improvement across the organization by communicating process changes clearly and effectively. 
  • Serve as a resource and mentor to Document Control and Change Control staff on best practices and quality system requirements. 

Supplemental Functions: 

  • Assist in Quality Assurance approval of Change controls in Quality Management System for documents,      materials and equipment/process changes.
  • Review revision of controlled documents to ensure compliance with the regulatory submissions and requirements.
  • Participate in management review meetings by presenting quality metrics and improvement initiative status updates. 
  • Maintain a high level of confidentiality with respect to Nephron and employee information. 
  • Participate in cross-functional project teams as a quality systems subject matter expert. 
  • Perform other job-related duties as assigned. 

Job Specifications and Qualifications: 

  • Associate or Bachelor's degree in Business Administration, Life Sciences, or a related field.
  • 3-4 years of experience in document control and/or Quality Assurance within a regulated environment (pharmaceutical, biotechnology, or related industry).
  • Working knowledge of cGMP, FDA regulations, and data integrity principles.
  • Minimum 3 years of experience with Document Management Systems (e.g., TrackWise, TrackWise Digital, Dot Compliance, Electronic Batch Records).
  • Experience with batch record lifecycle management, including generation, issuance, reconciliation, and archival. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and Adobe Acrobat (PDF workflows). 
  • Strong attention to detail with excellent organizational and documentation skills. 
  • Effective written and verbal communication skills. 
  • Ability to manage multiple priorities, meet deadlines, and work independently in a fast-paced environment.

Knowledge & Skills: 

  • In-depth knowledge of document control and change control principles within a regulated pharmaceutical, biotechnology, or medical device environment. 
  • Strong understanding of cGMP, FDA 21 CFR Parts 211 and 820, ICH Q10, ISO 9001, and ISO 13485 regulatory requirements. 
  • Demonstrated experience applying continuous improvement methodologies to quality system processes. 
  • Proficiency with eQMS platforms (TrackWise, TrackWise Digital, Dot      Compliance) including workflow configuration and reporting. 
  • Strong data analysis skills with the ability to translate metrics into actionable improvement plans. 
  • Excellent technical writing skills with experience authoring SOPs, work instructions, and process maps. 
  • Strong project management skills with the ability to lead multiple improvement initiatives simultaneously. 
  • Effective communication and facilitation skills, with the ability to influence cross-functional stakeholders without direct authority. 
  • High attention to detail and commitment to accuracy, traceability, and compliance. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint, Visio) and data visualization  tools. 
  • Ability to work independently, prioritize effectively, and deliver results in a fast-paced, regulated environment. 

Education/Experience: 

  • Bachelor's degree in Life Sciences, Pharmacy, Engineering, Business Administration, or a related field required. 
  • Minimum 4-6 years of experience in Quality Assurance, Document Control, or Change Control within a regulated pharmaceutical, biotechnology, or medical device environment. 
  • Minimum 2-3 years of demonstrated experience leading or supporting continuous improvement initiatives within a quality systems function. 
  • Hands-on experience with eQMS platforms (e.g., TrackWise, Veeva Vault, MasterControl, Dot Compliance) required. 
  • Demonstrated experience managing document control processes, including document lifecycle management, data integrity, and records retention. 
  • Experience with batch record management, including generation, issuance, reconciliation, and archival. 
  • 3-4 years of leadership and/or project management experience, including team oversight and cross-functional coordination. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and Adobe Acrobat. 

Working Conditions / Physical Requirements:

  • This position requires frequent standing, sitting, walking, typing, and occasional bending and lifting of up to 40 lbs. throughout the facility. 
  • Ability to adapt to changing priorities and shift focus to meet evolving organizational and business needs. 
  • May be required to wear appropriate personal protective equipment (PPE) in designated areas. 
  • Standard work schedule is Monday through Friday, 8-hour shifts; additional hours may be required based on business demands.  

Job Purpose:

The Change Control Continuous Improvement Manager is responsible for identifying, developing, and implementing process improvement initiatives within the Change Control and Document Revision functions. This role serves as a subject matter expert (SME) and internal lead for optimizing document lifecycle management, change control workflows, and electronic quality management system (eQMS) performance.  

Essential Duties and Responsibilities:

1. Continuous Improvement - Change Control and Document Revision
  • Lead continuous improvement efforts for change management processes, including initiation, impact assessment, approval routing, implementation, and closure. 
  • Analyze data to identify bottlenecks, recurring delays, incomplete submissions, and systemic      compliance risks. 
  • Establish and monitor key performance indicators (KPIs) for change control and document revision cycle      time, on-time closure rates, and rejection rates. 
  • Collaborate with cross-functional stakeholders (Manufacturing, Engineering, Regulatory Affairs, Validation, and Quality) to ensure change control requirements are clearly understood and consistently applied. 
  • Conduct root cause analysis on change control deficiencies and implement corrective process improvements. 
2. eQMS System Optimization & Data Analysis
  • Serve as a functional lead and SME for the eQMS (Dot Compliance) as it relates to document control and change control modules. 
  • Generate and analyze quality system reports and dashboards to support management review, audit readiness, and performance trending. 
  • Identify and drive system configuration improvements to enhance workflow automation, routing efficiency, and compliance controls. 
  • Develop and maintain eQMS user training materials and deliver training to document control and change control end users.
3. Training & Change Management
  • Develop and deliver training programs on document control and change control processes, tools, and regulatory expectations. 
  • Champion a culture of quality and continuous improvement across the organization by communicating process changes clearly and effectively. 
  • Serve as a resource and mentor to Document Control and Change Control staff on best practices and quality system requirements. 

Supplemental Functions: 

  • Assist in Quality Assurance approval of Change controls in Quality Management System for documents, materials and equipment/process changes.
  • Review revision of controlled documents to ensure compliance with the regulatory submissions and requirements.
  • Participate in management review meetings by presenting quality metrics and improvement initiative status updates. 
  • Maintain a high level of confidentiality with respect to Nephron and employee information. 
  • Participate in cross-functional project teams as a quality systems subject matter expert. 
  • Perform other job-related duties as assigned. 

Job Specifications and Qualifications: 

  • Associate or Bachelor's degree in Business Administration, Life Sciences, or a related field.
  • 3-4 years of experience in document control and/or Quality Assurance within a regulated environment (pharmaceutical, biotechnology, or related industry).
  • Working knowledge of cGMP, FDA regulations, and data integrity principles.
  • Minimum 3 years of experience with Document Management Systems (e.g., TrackWise, TrackWise Digital, Dot Compliance, Electronic Batch Records).
  • Experience with batch record lifecycle management, including generation, issuance, reconciliation, and archival. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and Adobe Acrobat (PDF workflows). 
  • Strong attention to detail with excellent organizational and documentation skills. 
  • Effective written and verbal communication skills. 
  • Ability to manage multiple priorities, meet deadlines, and work independently in a fast-paced environment.

Knowledge & Skills: 

  • In-depth knowledge of document control and change control principles within a regulated pharmaceutical, biotechnology, or medical device environment. 
  • Strong understanding of cGMP, FDA 21 CFR Parts 211 and 820, ICH Q10, ISO 9001, and ISO 13485 regulatory requirements. 
  • Demonstrated experience applying continuous improvement methodologies to quality system processes. 
  • Proficiency with eQMS platforms (TrackWise, TrackWise Digital, Dot Compliance) including workflow configuration and reporting. 
  • Strong data analysis skills with the ability to translate metrics into actionable improvement plans. 
  • Excellent technical writing skills with experience authoring SOPs, work instructions, and process maps. 
  • Strong project management skills with the ability to lead multiple improvement initiatives simultaneously. 
  • Effective communication and facilitation skills, with the ability to influence cross-functional stakeholders without direct authority. 
  • High attention to detail and commitment to accuracy, traceability, and compliance. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint, Visio) and data visualization tools. 
  • Ability to work independently, prioritize effectively, and deliver results in a fast-paced, regulated environment. 

Education/Experience: 

  • Bachelor's degree in Life Sciences, Pharmacy, Engineering, Business Administration, or a related field required. 
  • Minimum 4-6 years of experience in Quality Assurance, Document Control, or Change Control within a regulated pharmaceutical, biotechnology, or medical      device environment. 
  • Minimum 2-3 years of demonstrated experience leading or supporting continuous improvement initiatives within a quality systems function. 
  • Hands-on experience with eQMS platforms (e.g., TrackWise, Veeva Vault, MasterControl, Dot Compliance) required. 
  • Demonstrated experience managing document control processes, including document lifecycle management, data integrity, and records retention. 
  • Experience with batch record management, including generation, issuance, reconciliation, and archival. 
  • 3-4 years of leadership and/or project management experience, including team oversight and cross-functional coordination. 
  • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and Adobe Acrobat. 

Working Conditions / Physical Requirements:

  • This position requires frequent standing, sitting, walking, typing, and occasional bending and lifting of up to 40 lbs. throughout the facility. 
  • Ability to adapt to changing priorities and shift focus to meet evolving organizational and business needs. 
  • May be required to wear appropriate personal protective equipment (PPE) in designated areas. 
  • Standard work schedule is Monday through Friday, 8-hour shifts; additional hours may be required based on business demands.