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"Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky"

Mineralys is a fully remote company.

National Sales Director

The National Sales Director (NSD) will serve as a senior field leader responsible for building and leading a high-performing commercial organization across a large U.S. geography in support of Mineralys' first product launch. This role will lead a team of Regional Sales Directors and their sales teams, ensuring flawless launch execution, strong customer engagement, and achievement of business objectives.

The NSD will act as a strategic business partner to the VP of Sales and cross-functional leadership team, helping shape launch strategy, field execution plans, talent development, and organizational culture. This role requires a seasoned leader with deep launch experience, strong business acumen, and the ability to scale teams in a fast-paced biotech environment.

Key Responsibilities

Commercial Strategy / Launch Leadership

• Lead launch planning and execution across assigned area to ensure achievement of sales, market access, and market share goals
• Translate national commercial strategy into actionable area business plans and execution priorities
• Monitor business performance, identify risks/opportunities, and implement corrective actions quickly
• Drive launch excellence, customer engagement, and field execution consistency
• Provide ongoing market insights and competitive intelligence to commercial leadership

Field Leadership / Team Development

• Recruit, onboard, and develop Regional Sales Directors (RSD) and support their hiring of top field talent
• Lead, coach, and develop a team of approximately 15 RSDs and indirect oversight of 50-100+ field representatives
• Establish a high-performance culture focused on accountability, collaboration, and execution
• Conduct regular field coaching, business reviews, and talent assessments
• Build leadership bench strength and succession plans

Cross-Functional Partnership

• Partner closely with Market Access, Marketing, Medical Affairs, Training, Operations, Compliance, and HR to support launch readiness and sustained execution
• Collaborate with Area Sales Director peers and VP of Sales to ensure national alignment and share best practices
• Support national sales meetings, launch planning sessions, and leadership forums
• Partner with Market Access on payer, IDN, and organized customer strategy as needed

Business Operations / Compliance

• Manage area budget, resources, and deployment plans
• Ensure forecasting accuracy, CRM utilization, and performance reporting
• Drive compliance with all company policies, industry regulations, and legal requirements
• Promote Mineralys' values of collaboration, integrity, quality, trust, and urgency

Qualifications

• Bachelor's degree required; advanced degree preferred
• 12+ years of pharmaceutical / biotech sales experience
• 5+ years of field sales leadership experience, including leadership of leaders
• Prior launch experience required; first-launch / emerging biotech experience strongly preferred
• Demonstrated success leading specialty sales organizations and exceeding performance goals
• Experience in cardiovascular, nephrology, hypertension, or related specialty markets strongly preferred
• Strong coaching, talent assessment, and leadership development skills
• Proven ability to work cross-functionally and influence without authority
• Strong business planning, analytical, and problem-solving skills
• Ability to travel extensively within area and nationally as needed

Leadership Profile

• A builder who thrives in creating infrastructure and scaling teams
• A visible, hands-on leader who drives accountability and results
• Agile and comfortable with ambiguity in a launch environment
• Highly collaborative and able to influence across the organization
• Passionate about developing talent and building culture

Travel

• This position requires up to 60% travel. Frequently travel is outside the local area and overnight.

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $260,000 - $285,000

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