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Scientist II - Assay Development

Boston, MA · On-site

$50 - $56/hr

Merck discovers, develops, manufactures, and markets a broad range of innovative products to ... You can put your empathy, creativity, digital mastery or scientific genius to work in collaboration ...

Merck & Co.

... Clinical Sciences and Study Management (CSSM), Regulatory, CMC, Pharmaceutical Sciences ... Merck marketed drug product planning activities for new protocols ----Serves in a support or lead ...

Merck

Engineering Supervisor

Jaffrey, NH · On-site

... are, Life Science and Electronics. For more than 350 years and across the world we have ... MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany. Your Role: At MilliporeSigma, the ...

MSD Malaysia

Senior Scientist, Biostatistics

Rahway, NJ · On-site

$117 - $184/hr

Senior Scientist, Biostatistics - Rahway, NJ: * Serve as statistical representative in the cross ... Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA,

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How much do merck scientist jobs pay per hour?

As of Aug 25, 2026, the average hourly pay for merck scientist in the United States is $35.23, according to ZipRecruiter salary data. Most workers in this role earn between $25.00 and $45.67 per hour, depending on experience, location, and employer.

What is a Merck Scientist?

A Merck Scientist is a research professional who conducts experiments and develops new pharmaceutical products, vaccines, or therapies. They work in laboratory settings, analyzing data and ensuring compliance with regulatory standards. Scientists at Merck collaborate with cross-functional teams to advance drug discovery and improve patient outcomes. Their role may involve molecular biology, chemistry, bioinformatics, or other scientific disciplines.

What types of projects and team collaborations can a Merck Scientist typically expect?

As a Merck Scientist, you can expect to work on a diverse range of projects including drug discovery, process optimization, and clinical research support. Collaboration is a key aspect of the role; you'll often work within cross-functional teams involving chemists, biologists, data scientists, and regulatory professionals. Daily responsibilities may include designing experiments, analyzing results, documenting findings, and presenting data to both scientific and non-scientific stakeholders. This collaborative and project-driven environment offers significant opportunities for learning, professional development, and advancement into leadership or specialized technical roles.

What are the key skills and qualifications needed to thrive in the Merck Scientist position, and why are they important?

To thrive as a Merck Scientist, you generally need a strong background in scientific research, data analysis, and a relevant advanced degree such as a Ph.D. or M.S. in fields like biology, chemistry, or pharmaceutical sciences. Familiarity with laboratory information management systems (LIMS), specialized analytical instruments, and compliance with GLP/GMP standards is often required. Strong teamwork, communication, and problem-solving abilities help set top candidates apart. These skills are crucial for advancing innovative research, ensuring regulatory compliance, and enabling effective collaboration in dynamic, multidisciplinary environments.

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Merck Scientist jobs near you
Infographic showing various Merck Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 12% Part Time, and 4% Contract. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $73,278 per year, or $35.2 per hour.

Scientist II - Assay Development

Merck

Boston, MA • On-site

$50 - $56/hr

Temporary

Medical, Dental, Vision, Life, Retirement

Posted 6 days ago

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Merck rating

8.0

Company rating: 8.0 out of 10

Based on 51 frontline employees who took The Breakroom Quiz

43rd of 86 rated pharmaceutical

Job description

Join the Biochemistry and Biophysics Group within the Department of Pharmacology at MRL-Boston for an exciting opportunity to advance early-stage drug discovery. In this role, you will collaborate closely with a dynamic, cross-functional scientific team dedicated to identifying and optimizing small molecule therapeutics. You will play a key part in characterizing target proteins and small molecule interactions, leveraging cutting-edge biochemical and biophysical methodologies to drive medicinal chemistry and high-throughput screening initiatives forward.

Responsibilities

  • Develop, optimize, and run quantitative biochemical and biophysical assays to support small molecule ligand identification and lead optimization.
  • Conduct detailed biochemical and biophysical studies to elucidate mechanisms of action and modes of ligand-protein interactions.
  • Support high-throughput screening (HTS) campaigns and ongoing medicinal chemistry efforts through robust compound profiling.
  • Utilize advanced detection modalities to characterize target-ligand binding dynamics and enzymatic behavior.
  • Perform steady-state and transient-state kinetic experiments to evaluate enzyme and inhibitor mechanisms.
  • Operate and integrate automated liquid handlers to streamline assay throughput and compound handling.
  • Analyze complex screening data using specialized analytical software and present findings clear and concisely to team members.
  • Maintain detailed scientific records, trouble-shoot experimental workflows, and contribute to continuous laboratory optimization.

Education

  • BS/BA degree in biochemistry, biophysics, or a related scientific discipline with 1–5 years of industry experience; OR
  • MS degree in biochemistry, biophysics, or a related scientific discipline with 1+ years of industry experience (preferably focused on assay development and compound profiling in drug discovery).

Experience

  • Solid foundational knowledge in biochemistry, biophysics, and molecular biology with practical experience in basic biochemical and biophysical techniques.
  • Demonstrated hands-on experience in assay development utilizing modalities such as TR-FRET, FP, LC-MS, radiochemical, SPR (BIAcore), fluorescence thermal shift (TdF), or ITC.
  • Prior hands-on experience executing enzyme and inhibitor kinetic studies (steady-state and transient-state).
  • Experience operating automated liquid handling platforms (e.g., Echo, Bravo, Biomek, or Hamilton).
  • Proficiency with Windows OS, data analysis databases, and presentation applications including Excel, PowerPoint, and TIBCO Spotfire.

Company Description

Merck Sharp & Dohme Corp. ("Merck") is a leading research-driven pharmaceutical products and services company. Merck discovers, develops, manufactures, and markets a broad range of innovative products to improve human health, directly and through its joint ventures

Imagine getting up in the morning for a job as important as saving and improving lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery or scientific genius to work in collaboration with other like-minded colleagues to pursue and bring hope to countless people who are battling the most challenging diseases of our time. Our team is always evolving, so if you are among the intellectually curious, join us—and start making your impact today.

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