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Crispr Scientist Jobs (NOW HIRING)

Crispr Therapeutics

Scientist II, LNP

South Boston, MA · On-site

$130K - $140K/yr

CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies ... Position Summary We are seeking a highly motivated Scientist II to join our LNP team. This is a ...

Crispr Therapeutics

Director, LNP Discovery

Boston, MA

$195K - $215K/yr

The Nobel Prize-winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially ...

Crispr Therapeutics

Scientist II, LNP

Boston, MA · On-site

$130K - $140K/yr

CRISPR Therapeuticsis advancing a broad and diversified pipeline across hemoglobinopathies ... Position Summary We are seeking a highly motivated Scientist II to join our LNP team. This is a ...

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How much do crispr scientist jobs pay per year?

As of Aug 28, 2026, the average yearly pay for crispr scientist in the United States is $130,117.00, according to ZipRecruiter salary data. Most workers in this role earn between $107,500.00 and $173,000.00 per year, depending on experience, location, and employer.

What does a CRISPR scientist do?

A CRISPR scientist researches and develops applications using CRISPR gene-editing technology. Their work involves designing experiments to modify genetic material in cells or organisms, analyzing results, and ensuring the accuracy and safety of genetic edits. CRISPR scientists may work in academic, medical, or biotechnology settings, contributing to advancements in medicine, agriculture, and biological research. They often collaborate with other scientists to explore new therapeutic approaches or improve crop traits.

What are the key skills and qualifications needed to thrive as a CRISPR scientist, and why are they important?

To thrive as a CRISPR Scientist, you need a strong background in molecular biology, genetics, and genome editing, typically supported by an advanced degree such as a PhD in a relevant field. Familiarity with CRISPR-Cas9 technologies, gene editing software, cell culture techniques, and laboratory information management systems (LIMS) is essential. Attention to detail, critical thinking, and effective collaboration are crucial soft skills for designing experiments and interpreting complex data. These competencies are vital for advancing precise gene-editing research and ensuring rigorous, reproducible scientific outcomes.

What are some common challenges faced by a CRISPR scientist when designing gene-editing experiments?

CRISPR Scientists often encounter challenges such as minimizing off-target effects, optimizing guide RNA design, and ensuring efficient delivery of editing components to target cells. Additionally, troubleshooting unexpected cellular responses and verifying precise genome edits can be time-consuming and require meticulous planning. Collaboration with bioinformaticians and molecular biologists is usually essential to overcome these obstacles and achieve robust, reproducible results.

What is the difference between Crispr Scientist vs Gene Editing Researcher?

AspectCrispr ScientistGene Editing Researcher
CredentialsAdvanced degrees in molecular biology, genetics, or related fields; experience with CRISPR technologySimilar credentials; expertise in gene editing techniques, including CRISPR
Work EnvironmentLaboratories focused on genetic modification, biotech companies, research institutionsResearch labs, biotech firms, academic settings
Industry UsagePrimarily in biotech, pharmaceuticals, agriculture, and researchSimilar industries, often overlapping in research projects

Both roles involve genetic modification techniques, with a focus on CRISPR technology. A Crispr Scientist specializes specifically in CRISPR-based methods, while a Gene Editing Researcher may work with various gene editing tools, including but not limited to CRISPR. The roles often overlap in credentials and work environment, but the Crispr Scientist emphasizes expertise in CRISPR technology.

How much does a CRISPR scientist make?

CRISPR scientists typically earn between $70,000 and $130,000 annually, depending on experience, education, and location. Senior roles or those with specialized skills in gene editing and molecular biology can earn higher salaries, especially in research institutions or biotech companies.

What degree do I need to work with CRISPR?

A CRISPR scientist typically needs at least a bachelor's degree in a relevant field such as molecular biology, genetics, biochemistry, or biotechnology. Advanced roles often require a master's or Ph.D. with experience in gene editing techniques, laboratory skills, and familiarity with CRISPR tools and protocols.
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Crispr Scientist jobs near you
Infographic showing various Crispr Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 12% Part Time, and 4% Contract. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $130,117 per year, or $62.6 per hour.

Scientist II, LNP

Crispr Therapeutics

South Boston, MA • On-site

$130K - $140K/yr

Full-time

Re-posted 17 days ago

Job description

Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
We are seeking a highly motivated Scientist II to join our LNP team. This is a critical, hands-on laboratory role focused on the design, development, and characterization of novel nanoparticle delivery systems.
The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different nucleic acid payloads (such as mRNA, siRNA, etc.). Experience in the space of target delivery or extra-hepatic delivery strategies is highly desirable. You will be part of a team responsible for driving the development of our delivery platform, from initial concept and screening through in vivo proof of concept studies.
Responsibilities
  • Design, formulate and optimize novel lipid nanoparticle (LNP) compositions through different production methods and scale.
  • Perform comprehensive analytical characterization of nanoparticles including but not limited to size, zeta potential, morphology, payload and lipid quantification, encapsulation efficiency, etc.
  • Develop and execute bioconjugation strategies to functionalize LNP surfaces with targeting ligands of different sizes or nature.
  • Analyze, interpret and present complex experimental data clearly and concisely at team and company meetings.
  • Work closely with cross-functional teams to design and execute experiments that evaluate formulation performance, toxicity, and efficacy.
  • Stay current with scientific literature, troubleshoot technical challenges, and proactively evaluate new technologies to improve our delivery platform.
  • Maintain meticulous and accurate electronic laboratory notebooks (ELN) and contribute to technical reports and regulatory filings.
  • Collaborate with IP counsels to support CRISPR Therapeutics patent applications and prosecutions

Minimum Qualifications
  • Degree in Pharmaceutical Sciences, Biomedical Engineering, Chemical Engineering, Chemistry, or a related field with PhD with 2-5 years of relevant experience or postdoctoral experience or non-PhD with 10-12+ years of relevant experience
  • Deep, hands-on experience in the formulation of lipid nanoparticles or similar non-viral delivery systems.
  • Demonstrated experience with encapsulating nucleic acids and associated analytical techniques.
  • Experience with bioconjugation chemistry and protein modification and purification.
  • Proficiency in nanoparticle characterization techniques.
  • Strong problem-solving skills and the ability to design experiments independently.
  • Excellent communication skills and a highly collaborative, team-oriented mindset.

Preferred Qualifications
  • Knowledge of LNP process development, scale-up and stability testing.
  • Experience with HPLC/UPLC for lipid and payload analysis.
  • Familiar with in vivo models for evaluating drug delivery systems.
  • Experience working in a fast-paced biotech or pharmaceutical industry environment.
  • Understanding of Design of Experiments (DoE) principles

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Scientist II: Base pay range of $130,000 to $140,000+ bonus, equity and benefits
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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