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Phage Display Scientist Jobs (NOW HIRING)

Fortis Life Sciences

Research Associate

San Diego, CA · On-site

$20 - $25/hr

The Opportunity Fortis is a global leader in life sciences and diagnostics reagents and solutions ... culture, phage culture, phage display affinity selections, small-scale protein production and ...

Vistera Inc

Senior Scientist, Research

Waltham, MA · On-site

$152K - $183K/yr

Summary Visterra, Inc. is seeking to hire a Senior Scientist with strong expertise in immunology ... Experience with antibody discovery platforms, such as phage display, yeast display, and next ...

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Phage Display Scientist information

What are the key skills and qualifications needed to thrive in the Phage Display Scientist position, and why are they important?

Phage Display Scientists require a strong background in molecular biology, protein engineering, and biochemistry, typically supported by a Ph.D. or relevant research experience. Familiarity with phage display technology, high-throughput screening platforms, and laboratory data analysis software is commonly expected. Excellent problem-solving abilities, attention to detail, and effective collaboration skills are highly valued soft skills in this field. These competencies are essential for driving innovative research, ensuring experimental accuracy, and delivering successful project outcomes in fast-paced biotech environments.

What are some typical daily responsibilities for a Phage Display Scientist?

Phage Display Scientists typically design and execute experiments to construct and screen phage libraries, analyze binding affinities, and optimize target-specific molecules. Their daily work often involves extensive benchwork, data analysis, and meticulous documentation of results. Collaboration with multidisciplinary teams, such as bioinformaticians or project managers, is common to interpret findings and drive projects forward. Additionally, scientists may present their results at meetings and contribute to scientific publications, providing valuable input to drug discovery or therapeutic programs.

What is a Phage Display Scientist job?

A Phage Display Scientist specializes in using phage display technology to identify and engineer peptides, proteins, or antibodies for therapeutic, diagnostic, or research applications. They design and perform library screenings, optimize binding interactions, and analyze candidate molecules. This role requires expertise in molecular biology, biochemistry, and bioinformatics. Scientists in this field work in pharmaceutical, biotechnology, or academic settings to develop novel therapeutics or biomarkers.

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Scientist, Phage Display & Discovery

Scientist, Phage Display & Discovery

Manifold Bio

Boston, MA • On-site

$118K - $138K/yr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 27 days ago

Job description

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match. The datasets power our computational models, which leads to better drug designs, creating a flywheel that gets stronger with every campaign. Our team of protein engineers, biologists, and computational scientists works across this full stack to pursue programs both internally and with leading pharma companies.
Position

We are seeking an exceptional scientist with expertise in library-based methodologies and substantial wet-lab experience to join our team. In this role, you will lead comprehensive library-based projects from conception to completion, engineering therapeutic proteins with transformative potential. You will develop and execute novel high-throughput screening assays, design and construct DNA libraries using advanced cloning techniques, and analyze complex library screens, including massively parallel in vivo screens powered by our proprietary mCode protein barcoding technology. You will work with a highly interdisciplinary team of creative experimental, computational, and hybrid scientists to advance high-throughput protein engineering and synthetic biology initiatives. As a key member of our growing company, you will contribute to building a culture that embraces scientific boldness and a strong team-focused approach to solving problems.

Required Qualifications

Wet Lab Expertise:

  • Masters/PhD or equivalent experience in molecular biology, bioengineering, or a related field.
  • Proficiency in standard molecular biology techniques and protocols.
  • Hands-on experience with phage-based display approaches.
  • Experience designing and constructing diverse DNA libraries for protein engineering applications.
  • Proven capability in library-based protein engineering, including experience with high-throughput or multiplexed assay formats.
  • Skilled in designing, executing, and analyzing complex experimental workflows from end to end.

Core Competencies:

  • Detail-oriented with exceptional organizational and communication skills.
  • Curious and flexible, with a strong desire to work collaboratively within a fast-paced and multidisciplinary team environment.
  • A love for tinkering with biological parts and solving challenges to develop novel assays.
  • Enthusiasm for combining rational design with unbiased approaches to problem-solving.
Preferred Qualifications
  • 2+ years of start-up, biotech, or pharma experience in protein engineering or assay development.
  • Direct experience with display technologies and selections including phage, yeast, and/or ribosome display.
  • Hands-on experience with generating and maintaining overexpression cell lines.
  • Hands-on experience with Next Geneneration Sequencing (NGS).
  • Experience with handling/processing animal tissues.
  • Experience developing or engineering brain shuttle technologies for improved blood-brain barrier transport.
  • Familiarity with screening-based methods with an NGS readout, e.g. DMS, MPRA, CRISPR screening, cancer screens, single cell sequencing.
  • Experience with data analysis (Python or R).

Base Salary Range: $118,000-138,000

This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate's experience, interview performance, and expected impact.

This role is eligible for:

  • Annual performance-based target bonus
  • Stock options
  • Comprehensive medical, dental, and vision coverage
  • 401(k) plan
  • Flexible paid time off and holidays
  • Perks including on-site gym, onsite lunch, and commuter support

Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.

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