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Full Time Phage Display Scientist Jobs (NOW HIRING)

Repligen Corporation

Scientist I

Lebanon, NH · On-site

$84K - $121K/yr

As a Scientist I in the Ligand Discovery Group, you will participate in the identification and ... The ideal candidate possesses strong molecular biology skills and experience with phage display ...

Repligen

Scientist I

Lebanon, NH · On-site

$84K - $121K/yr

As a Scientist I in the Ligand Discovery Group, you will participate in the identification and ... The ideal candidate possesses strong molecular biology skills and experience with phage display ...

New

Repligen

$84K - $121K/yr

As a Scientist I in the Ligand Discovery Group, you will participate in the identification and ... The ideal candidate possesses strong molecular biology skills and experience with phage display ...

New

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Full Time Phage Display Scientist information

What does a full time phage display scientist do?

A Full Time Phage Display Scientist specializes in using phage display technology to discover and engineer proteins, such as antibodies or peptides, for research, diagnostics, or therapeutic applications. They design, construct, and screen phage libraries to identify molecules with desired binding properties. Their role often involves molecular biology techniques, data analysis, and collaboration with other scientists to optimize and validate candidates for further development.

What are some typical challenges faced by a full time phage display scientist when optimizing antibody selection campaigns?

A Full Time Phage Display Scientist often encounters challenges such as balancing library diversity with screening sensitivity, minimizing background binding, and ensuring selected antibodies have both high affinity and specificity. Additionally, troubleshooting unexpected results—like non-specific binders or low recovery rates—requires a strong understanding of molecular biology techniques and data analysis. Collaboration with protein expression teams and bioinformaticians is key to overcoming these obstacles and advancing candidates for further development.

What are the key skills and qualifications needed to thrive as a full time phage display scientist, and why are they important?

To excel as a Full Time Phage Display Scientist, you typically need a strong background in molecular biology, biochemistry, and protein engineering, often supported by a PhD or relevant research experience. Expertise in phage display libraries, ELISA, DNA manipulation, and familiarity with laboratory information management systems (LIMS) is commonly required. Critical thinking, strong problem-solving skills, and effective collaboration are valuable soft skills in this role. These abilities ensure the successful design, execution, and analysis of experiments that drive innovation in antibody discovery and therapeutic development.

What is the difference between Full Time Phage Display Scientist vs Research Associate in Molecular Biology?

AspectFull Time Phage Display ScientistResearch Associate in Molecular Biology
Required CredentialsBachelor's or Master's in Biology, Biochemistry, or related field; experience in phage display techniquesBachelor's or Master's in Biology, Biochemistry, or related field; laboratory experience in molecular biology
Work EnvironmentBiotech or pharmaceutical labs focusing on antibody discovery and protein engineeringAcademic or industry labs conducting molecular biology research
Employer & Industry UsageBiotech companies, pharmaceutical firms, research institutionsUniversities, research institutes, biotech companies

The main difference is that a Full Time Phage Display Scientist specializes specifically in phage display techniques for antibody development, requiring specialized experience. In contrast, a Research Associate in Molecular Biology has a broader focus on molecular biology techniques without necessarily specializing in phage display. Both roles require laboratory experience and are found in similar industry settings, but the Phage Display Scientist role is more specialized.

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Full Time Phage Display Scientist jobs near you
Infographic showing various Full Time Phage Display Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 64% Full Time, 31% Part Time, and 4% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution.

Scientist I, Display Technologies

BigHat Biosciences

San Mateo, CA • On-site

$120K - $145K/yr

Full-time

Posted 16 days ago

Key responsibilities

  • Support R&D projects advancing display technologies and contribute to antibody discovery efforts.

  • Construct, QC, and execute phage display selections to engineer antibodies with desired properties.

  • Express, purify, characterize display-derived molecules, and analyze selection results to inform future experiments.

Job description

Scientist I, Display Technologies
Department: Lab Science
Employment Type: Full Time
Location: San Mateo, CA
Description
The role: BigHat Biosciences is seeking a curious and motivated Scientist 1 to join the Display Technologies team. This individual will contribute to BigHat's antibody discovery and engineering efforts and help generate high-quality data to improve BigHat's machine learning models using display technologies, working closely with senior scientists and cross-functional teams.
Key Responsibilities
  • Support R&D projects advancing display technologies at BigHat that expands BigHat's antibody discovery capabilities and feed its ML models.
  • Lead in the construction and QC of phage display libraries across diverse antibody formats (VHH, scFv, Fab) using standard molecular biology techniques (PCR, molecular cloning, electroporation).
  • Execute standard phage display selections to engineer antibodies with desired therapeutic properties.
  • Express, purify, and characterize display-derived molecules using assays including ELISA, flow cytometry, BLI/SPR, CE-SDS, and others.
  • Analyze selection results and contribute to discussions on next steps and future experimental design.
  • Collaborate with BigHat's Data Science and Machine Learning teams to inform library design and interpret selection data for model training.
  • Collaborate closely with BigHat leadership and other cross-functional team members to ensure a tight linkage between strategy, research, and development components.
  • Present experimental plans and results during regular meetings with manager and science teams.
  • Effectively and regularly communicate results to key decision makers, the broader BigHat team, and to external partners.
  • Maintain thorough records using LIMS and electronic notebooks.

Skills Knowledge and Expertise
  • Ph.D. in Biochemistry, Structural Biology, Protein Engineering, or a related field, with up to 2 years of industry research experience; or an M.S. in a related field with 6+ years of relevant industry research experience.
  • Experience with display technologies, including library design and selection strategies.
  • Knowledge of antibody biology and protein expression.
  • Strength in general molecular biology techniques (PCR, molecular cloning, gel electrophoresis).
  • Nice-to-haves include experience with flow cytometry, ELISA, or other binding assays, and familiarity with NGS or automation platforms.
  • Demonstrated ability to follow protocols carefully, troubleshoot experiments, and maintain detailed lab records.
  • Effective time management and clear written and verbal communication skills.
  • Collaborative, team-oriented mindset with an eagerness to learn in a fast-paced startup environment.
  • Scientific track record and publication record.
  • Strong data analysis and interpretation skills. Experience working with agentic software tools is a plus.

Total Rewards
The salary estimated for this position is $120,000 - $145,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

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