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Locum Rn Jobs in Irvine, CA (NOW HIRING)

KPG Nursing

Cath Lab in Long Beach, CA

Long Beach, CA · On-site

$2.8K/wk

Travel Cath Lab Registered Nurse - $2,894 per week in taxable pay and non-taxable stipend amount ... Our Services include Travel Nursing, Allied Professionals, Per Diem Nurse Staffing, Locum Tenens ...

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All JobsLocum Rn JobsLocum Rn Jobs in Irvine, CA

Locum Rn information

See Irvine, CA salary details

$14

$65

$199

How much do locum rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for locum rn in Irvine, CA is $65.49, according to ZipRecruiter salary data. Most workers in this role earn between $36.35 and $76.22 per hour, depending on experience, location, and employer.

What is a Locum RN?

A Locum RN, or Locum Registered Nurse, is a qualified nurse who temporarily fills staffing gaps in healthcare facilities, such as hospitals, clinics, or nursing homes. They may cover for permanent staff members who are on leave, or help during periods of increased patient demand. Locum RNs perform all the standard duties of a registered nurse, including patient care, administering medications, and collaborating with healthcare teams. This type of work offers flexibility and the opportunity to gain experience in different clinical environments.

What are the key skills and qualifications needed to thrive as a Locum RN?

To thrive as a Locum Registered Nurse (RN), you need a current RN license, a solid background in clinical care, and experience adapting quickly to new healthcare environments. Familiarity with various electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are typically required. Strong communication, adaptability, and problem-solving skills help locum RNs integrate smoothly into diverse teams and deliver quality patient care. These competencies are crucial for providing consistent, high-quality nursing support across different facilities and ensuring patient safety during temporary assignments.

What are some common challenges faced by Locum RNs when adapting to new clinical settings?

Locum RNs often encounter unique challenges when integrating into unfamiliar healthcare environments, such as quickly learning new protocols, adapting to different electronic health record systems, and building rapport with established teams. Flexibility and strong communication skills are essential, as locum nurses must efficiently assess patient needs while adhering to facility-specific procedures. Despite these challenges, many locum RNs find the variety and exposure to diverse practices rewarding, and these experiences can strengthen their clinical versatility.

What is the difference between Locum Rn vs Staff Rn?

AspectLocum RnStaff Rn
CredentialsRegistered Nurse license, possibly specialized certificationsRegistered Nurse license, possibly specialized certifications
Work EnvironmentTemporary assignments in various healthcare settingsFull-time or part-time employment in a specific healthcare facility
Employer UsageStaffing agencies, hospitals, clinicsHospitals, clinics, healthcare facilities
Search IntentTemporary nursing jobs, short-term assignmentsPermanent or long-term nursing positions

In summary, a Locum Rn is a temporary nurse filling short-term staffing needs, often through agencies, while a Staff Rn is a full-time or part-time employee working consistently at a healthcare facility. Both roles require valid RN licensure and similar certifications, but their employment types and work environments differ significantly.

What are the most commonly searched types of Rn jobs in Irvine, CA?

The most popular types of Rn jobs in Irvine, CA are:

What are popular job titles related to Locum Rn jobs in Irvine, CA?

For Locum Rn jobs in Irvine, CA, the most frequently searched job titles are:

What job categories do people searching Locum Rn jobs in Irvine, CA look for?

The top searched job categories for Locum Rn jobs in Irvine, CA are:

What cities near Irvine, CA are hiring for Locum Rn jobs?

Cities near Irvine, CA with the most Locum Rn job openings:

Locum Rn jobs near you
Infographic showing various Locum Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 3% As Needed, 58% Full Time, 14% Part Time, and 25% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $136,227 per year, or $65.5 per hour.

Travel Nurse RN - Case Management - $2,443 per week (Hiring Immediately)

MediPro

Mission Viejo, CA • On-site

$2.4K/wk

Part-time

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

MediPro is seeking a travel nurse RN Case Management for a travel nursing job in Mission Viejo, California. Job Description & Requirements Specialty: Case Management Discipline: RN Start Date: 09/21/2026 Duration: 13 weeks 40 hours per week Shift: 8 hours Employment Type: Travel Job Description • Start date: ASAP • Floating Expectation: Float • Ratios: 1:25 • Years of experience REQ: 2-year acute medical Care Manager experience performing Care Coordination • First-timers accepted: No - requires travel experience, HARDSTOP • Weekend REQ: Weekend Rotation • CA state license: Yes • Pending License accepted: Yes, but must be licensed upon start date • RTO Restrictions: No more than 7 days Hospital Highlights • Type of Facility: Acute Care Facility • Scrub Color: Turquoise or Business Casual MediPro Job ID 292-3451805. Pay package is based on 8 hour shifts and 40.0 hours per week (subject to confirmation) with tax-free stipend amount to be determined. About MediPro It's time someone took care of you. Get concierge level service and access our database of hot jobs you'll absolutely love! We are here to take care of you! Travel Per Diem Permanent Placement Locum Local MediPro is a leading healthcare talent firm that provides top tier clinicians to medical facilities and practices nationwide. We focus on Travel Nursing, Advanced Practice, Allied Services, Surgical Services, and Case Management. MediPro focuses on custom solutions based on each client's unique needs ranging across per diem, master-booking, travel assignments, perm placement and temp-to-perm.5c143e31-5e48-4549-b638-05792d185386

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