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Independent Contractor Rn Jobs in Irvine, CA (NOW HIRING)

SYNERGY STAFFING LLC

Registered Nurse

Irvine, CA · On-site

$50 - $80/hr

Registered Nurse (RN) - Home IV Infusion Nurse Irvine & surrounding areas Per Diem / Part-Time / ... If you enjoy one-on-one patient care, working independently, and using your IV skills in a ...

SYNERGY STAFFING LLC

Registered Nurse

Irvine, CA · On-site

$50 - $80/hr

If you enjoy one-on-one patient care, working independently, and using your IV skills in a ... Active California RN license in good standing * IV infusion experience required (home care ...

SYNERGY STAFFING LLC

Registered Nurse

Buena Park, CA · On-site

$50 - $80/hr

If you enjoy one-on-one patient care, working independently, and using your IV skills in a ... Active California RN license in good standing * IV infusion experience required (home care ...

SYNERGY STAFFING LLC

Registered Nurse

La Verne, CA · On-site

$60/hr

Registered Nurse (RN) - Home IV Infusion Nurse Pomona & surrounding areas Per Diem / Part-Time / ... If you enjoy one-on-one patient care, working independently, and using your IV skills in a ...

SYNERGY STAFFING LLC

Registered Nurse

Irvine, CA · On-site

$50 - $80/hr

Registered Nurse (RN) - Home IV Infusion Nurse Irvine & surrounding areas Per Diem / Part-Time / ... If you enjoy one-on-one patient care, working independently, and using your IV skills in a ...

Remedy Cares

Registered Nurse

Huntington Beach, CA · On-site

$110 - $140/hr

Meaningful Patient Care - Help patients recover, regain independence, and improve quality of life Home Health RN Responsibilities * Provide skilled nursing care in patient homes, including ...

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All JobsIndependent Contractor Rn JobsIndependent Contractor Rn Jobs in Irvine, CA

Independent Contractor Rn information

See Irvine, CA salary details

$423

$1.2K

$2.2K

How much do independent contractor rn jobs pay per week?

As of Jul 26, 2026, the average weekly pay for independent contractor rn in Irvine, CA is $1,169.27, according to ZipRecruiter salary data. Most workers in this role earn between $775.00 and $1,300.00 per week, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an Independent Contractor RN, and why are they important?

To thrive as an Independent Contractor RN, you need a current RN license, strong clinical assessment skills, and experience in your specialty area. Familiarity with telehealth platforms, electronic health records (EHRs), and compliance with healthcare regulations is crucial. Outstanding self-motivation, organizational skills, and effective communication help you manage multiple clients and coordinate care independently. These capabilities ensure safe, high-quality patient care while maintaining the flexibility and accountability required in contract-based roles.

How does working as an Independent Contractor RN differ from traditional staff nursing roles in terms of scheduling and autonomy?

As an Independent Contractor RN, you have greater flexibility over your schedule and the types of assignments you accept compared to traditional staff nurses. This autonomy allows you to choose when and where you work, which can improve work-life balance. However, you'll also be responsible for managing your own contracts, negotiating rates, and handling administrative tasks such as maintaining licensure and obtaining malpractice insurance. While this role offers more independence, it can also present challenges such as inconsistent work availability and less access to employer-provided benefits.

What are Independent Contractor RNs?

Independent Contractor RNs are registered nurses who work on a contract basis rather than as traditional employees. They often provide nursing services to various healthcare facilities, home health agencies, or private clients, managing their own schedules and business operations. This role allows for greater flexibility and autonomy but also requires handling self-employment responsibilities such as taxes, insurance, and securing contracts with clients.

What is the difference between Independent Contractor Rn vs Staff Nurse?

AspectIndependent Contractor RnStaff Nurse
CredentialsRN license, possibly specialized certificationsRN license, possibly specialized certifications
Work EnvironmentFreelance, temporary, or per-project basisHospital, clinic, or healthcare facility
Employer & Industry UsageSelf-employed, contracts with healthcare facilitiesEmployed by healthcare institutions
Work FlexibilityHigh; set own hours and assignmentsScheduled shifts, less flexibility

Independent Contractor Rns typically work independently, contracting with healthcare providers, offering flexibility and varied assignments. Staff Nurses are employed by healthcare facilities with fixed schedules. The main difference lies in employment status, work setup, and flexibility.

What are the most commonly searched types of Rn jobs in Irvine, CA? The most popular types of Rn jobs in Irvine, CA are:
What are popular job titles related to Independent Contractor Rn jobs in Irvine, CA? For Independent Contractor Rn jobs in Irvine, CA, the most frequently searched job titles are:
What job categories do people searching Independent Contractor Rn jobs in Irvine, CA look for? The top searched job categories for Independent Contractor Rn jobs in Irvine, CA are:
What cities near Irvine, CA are hiring for Independent Contractor Rn jobs? Cities near Irvine, CA with the most Independent Contractor Rn job openings:
Independent Contractor Rn jobs near you
Infographic showing various Independent Contractor Rn job openings in Irvine, CA as of July 2026, with employment types broken down into 42% Full Time, 29% Part Time, and 29% Contract. Highlights an 100% In-person job distribution, with an average salary of $60,802 per year, or $29.2 per hour.
Home Infusion Registered Nurse

Home Infusion Registered Nurse

Orbit Infusion Solutions

Lake Forest, CA • On-site

$60/hr

Part-time

Posted 25 days ago

Job description

Benefits:
  • Flexible schedule
  • Competitive salary
  • Free food & snacks

Home Infusion Registered Nurse (RN) – Independent Contractor (1099)

Exceptional Nurses. Exceptional Care.
Are you an experienced infusion, ICU, ER, oncology, or critical care nurse looking for a flexible opportunity that allows you to make a meaningful impact on patients' lives?
Orbit Infusion Solutions is a nurse-led infusion services company dedicated to delivering safe, compassionate, and clinically excellent infusion therapy in the comfort of patients' homes.
Unlike large staffing platforms, we believe in building lasting relationships with both our nurses and patients. Our team partners with specialty pharmacies, physicians, and healthcare organizations to provide high-quality specialty infusion services throughout California.
As an Independent Contractor RN, you'll have the freedom to choose the cases that fit your schedule while providing one-on-one care to medically complex patients who truly value your expertise.
What You'll Do
  •  Administer specialty infusion therapies in patients' homes and infusion suites 
  •  Start and maintain peripheral IV access 
  •  Assess patients before, during, and after infusion therapy 
  •  Monitor for adverse reactions and intervene appropriately 
  •  Provide patient and caregiver education 
  •  Complete accurate clinical documentation 
  •  Collaborate with specialty pharmacies, physicians, and care teams 
  •  Deliver safe, compassionate, patient-centered care 
Qualifications

Required:
  •  Active RN license (State or Compact) 
  •  Current BLS Certification 
  •  Professional Liability Insurance 
  •  Minimum 3-5 years of nursing experience 
Preferred Experience:

  •  Home Infusion 
  •  Infusion Center 
  •  Oncology 
  •  Critical Care 
  •  Emergency Department 
  •  Vascular Access 
  •  Pre-Op / PACU 
  •  Transport Nursing 
Why Nurses Choose Orbit
✔ Flexible scheduling — accept only the cases you want
✔ One-on-one patient care
✔ Competitive compensation
✔ Nurse-led leadership team
✔ Meaningful relationships with patients
✔ Clinical support when you need it
✔ Opportunities for growth as we expand
✔ Referral bonus program
Compensation
$60 per hour, depending on therapy, location, and experience
Our Core Values

Integrity • Compassion • Excellence • Accountability • Service
We believe patients deserve exceptional care and nurses deserve to be valued, respected, and supported.
If you're an experienced RN who takes pride in clinical excellence and enjoys caring for patients in a more personal setting, we'd love to connect with you.
Apply today to join the Orbit Infusion Solutions team.