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Locum Rn Jobs in Irvine, CA (NOW HIRING)

Solomon Page

Travel Labor and Delivery RN

Orange, CA · On-site

Discipline: RN * Start Date: 09/29/2026 * Duration: 13 weeks * 36 hours per week * Shift: 12 hours ... nurses, locum tenens, and allied resources. For more information and additional healthcare ...

Solomon Page

Travel Case Manager RN

Mission Viejo, CA · On-site

Discipline: RN * Start Date: 09/28/2026 * Duration: 26 weeks * 40 hours per week * Shift: 8 hours ... nurses, locum tenens, and allied resources. For more information and additional healthcare ...

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Solomon Page

Travel Case Manager RN

Mission Viejo, CA · On-site

Discipline: RN * Start Date: 09/28/2026 * Duration: 13 weeks * 40 hours per week * Shift: 8 hours ... nurses, locum tenens, and allied resources. For more information and additional healthcare ...

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All JobsLocum Rn JobsLocum Rn Jobs in Irvine, CA

Locum Rn information

See Irvine, CA salary details

$14

$65

$199

How much do locum rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for locum rn in Irvine, CA is $65.49, according to ZipRecruiter salary data. Most workers in this role earn between $36.35 and $76.22 per hour, depending on experience, location, and employer.

What is a Locum RN?

A Locum RN, or Locum Registered Nurse, is a qualified nurse who temporarily fills staffing gaps in healthcare facilities, such as hospitals, clinics, or nursing homes. They may cover for permanent staff members who are on leave, or help during periods of increased patient demand. Locum RNs perform all the standard duties of a registered nurse, including patient care, administering medications, and collaborating with healthcare teams. This type of work offers flexibility and the opportunity to gain experience in different clinical environments.

What are the key skills and qualifications needed to thrive as a Locum RN?

To thrive as a Locum Registered Nurse (RN), you need a current RN license, a solid background in clinical care, and experience adapting quickly to new healthcare environments. Familiarity with various electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are typically required. Strong communication, adaptability, and problem-solving skills help locum RNs integrate smoothly into diverse teams and deliver quality patient care. These competencies are crucial for providing consistent, high-quality nursing support across different facilities and ensuring patient safety during temporary assignments.

What are some common challenges faced by Locum RNs when adapting to new clinical settings?

Locum RNs often encounter unique challenges when integrating into unfamiliar healthcare environments, such as quickly learning new protocols, adapting to different electronic health record systems, and building rapport with established teams. Flexibility and strong communication skills are essential, as locum nurses must efficiently assess patient needs while adhering to facility-specific procedures. Despite these challenges, many locum RNs find the variety and exposure to diverse practices rewarding, and these experiences can strengthen their clinical versatility.

What is the difference between Locum Rn vs Staff Rn?

AspectLocum RnStaff Rn
CredentialsRegistered Nurse license, possibly specialized certificationsRegistered Nurse license, possibly specialized certifications
Work EnvironmentTemporary assignments in various healthcare settingsFull-time or part-time employment in a specific healthcare facility
Employer UsageStaffing agencies, hospitals, clinicsHospitals, clinics, healthcare facilities
Search IntentTemporary nursing jobs, short-term assignmentsPermanent or long-term nursing positions

In summary, a Locum Rn is a temporary nurse filling short-term staffing needs, often through agencies, while a Staff Rn is a full-time or part-time employee working consistently at a healthcare facility. Both roles require valid RN licensure and similar certifications, but their employment types and work environments differ significantly.

What are the most commonly searched types of Rn jobs in Irvine, CA?

The most popular types of Rn jobs in Irvine, CA are:

What are popular job titles related to Locum Rn jobs in Irvine, CA?

For Locum Rn jobs in Irvine, CA, the most frequently searched job titles are:

What job categories do people searching Locum Rn jobs in Irvine, CA look for?

The top searched job categories for Locum Rn jobs in Irvine, CA are:

What cities near Irvine, CA are hiring for Locum Rn jobs?

Cities near Irvine, CA with the most Locum Rn job openings:

Locum Rn jobs near you
Infographic showing various Locum Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 3% As Needed, 58% Full Time, 14% Part Time, and 25% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $136,227 per year, or $65.5 per hour.

CRNA - Anesthesiology job available in Downey, California

GHR Healthcare

Downey, CA

Full-time, Temporary

Medical, Dental, Vision, Retirement

Re-posted yesterday

Job description

Locum Tenens CRNA – General Anesthesia | Downey, CA (Hospital OR)

Locum Tenens CRNA – General Anesthesia in Downey, CA. Board-certified Certified Registered Nurse Anesthetist with 1+ year of CRNA OR experience needed for a full-time hospital operating room role — Monday–Friday, 8-hour days, no call.

Join a dynamic hospital anesthesia team at Downey Medical Center in Downey, California. This locum tenens CRNA opportunity offers collaborative, team-based care in a busy hospital setting serving the Los Angeles area. Enjoy a predictable weekday schedule and the lifestyle benefits of Southern California while providing high-quality perioperative anesthesia.

Job Details
  • Weekly Estimated Pay: 3,950 - 4,680
  • Location: Downey, CA 90242 — Downey Medical Center (Los Angeles area, Southern California)
  • Setting: Hospital – Operating Room coverage only (OR CRNA, hospital anesthesia)
  • Start Date: August 24, 2026
  • End Date: December 5, 2026
  • Schedule: Monday – Friday
  • Shift Duration: 8-hour days
  • Shifts Per Week: 5
  • Hours Per Week: 36
  • No Call Required
  • EMR: EPIC (Health Connect) — EPIC experience preferred
  • Role Type: Locum tenens CRNA job, hospital anesthesia position
Job Requirements
  • At least 1 year of CRNA experience in the operating room required
  • Board Certified Certified Registered Nurse Anesthetist (CRNA)
  • Current California CRNA license required
  • Vaccination preferred (waivers considered)
  • Ability to work collaboratively in a 1:3 MD supervision model (anesthesiologist supervision)
  • Credentialing timeframe: Estimated 90 days from application submission
Responsibilities
  • Provide safe, effective anesthesia care for general, orthopedic, urology, gynecology, gastroenterology, healthy pediatric, head and neck, thoracic, and interventional radiology cases
  • Deliver perioperative anesthesia services in the operating room (no labor and delivery coverage)
  • Manage approximately 3–8 cases per day depending on room assignment and schedule
  • Collaborate with surgeons, anesthesiologists, nursing, and OR support staff in a team-based care model
  • Document anesthesia care accurately and timely using EPIC EMR
Why Apply
  • Competitive weekly pay for locum tenens CRNA roles in California
  • Structured weekday schedule with no call — great work-life balance for CRNAs
  • Work in a hospital operating room environment serving the Los Angeles area
  • Opportunity to join a collaborative anesthesia team and gain California hospital experience

Apply now to be considered for this Downey, CA locum tenens CRNA position. Please submit your CV, current California CRNA license, and proof of board certification. Credentialing is estimated to take 90 days from application submission. Join our anesthesia team today!

Benefits

GHR Healthcare offers 401K with Matching, Healthcare, Dental and Vision to Employees. Company paid malpractice is available for 1099 Contractors. Weekly Direct Deposit is a standard benefit for both employees and contractors.

Equal Opportunity

We are an equal opportunity employer and value diversity across our organization. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

#LI-Onsite

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