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It Infrastructure Lead Jobs (NOW HIRING)

Dana-Co

IT Infrastructure Manager

Manhattan, NY · On-site

Lead the day-to-day management of our IT infrastructure, including servers, networking, Microsoft 365, Azure, storage, backups, endpoint management, and cloud services * Design, implement ...

Dana-Co

IT Infrastructure Manager

Manhattan, NY · On-site

$140 - $190/hr

Lead the day-to-day management of our IT infrastructure, including servers, networking, Microsoft 365, Azure, storage, backups, endpoint management, and cloud services * Design, implement ...

Dana-Co

IT Infrastructure Manager

Manhattan, NY · On-site

Lead the day-to-day management of our IT infrastructure, including servers, networking, Microsoft 365, Azure, storage, backups, endpoint management, and cloud services * Design, implement ...

Saronic Technologies

IT Infrastructure Manager

Austin, TX · On-site

$120 - $160/hr

Job Overview Saronic is seeking an IT Infrastructure Manager to lead our systems and network engineering teams. As the people manager for both teams, this role owns Saronic's corporate IT environment ...

LVT

Manager, IT Infrastructure

American Fork, UT · On-site

ABOUT THIS ROLE As the Manager of IT Infrastructure, you will lead the engineering crew responsible for the backbone of LVT's internal operations. You will champion the scaling, reliability, and ...

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It Infrastructure Lead information

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$11K

$137.9K

$225K

How much do it infrastructure lead jobs pay per year?

As of Sep 5, 2026, the average yearly pay for it infrastructure lead in the United States is $137,929.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,000.00 and $189,500.00 per year, depending on experience, location, and employer.

What is an IT Infrastructure Lead?

IT Infrastructure Leads are professionals responsible for overseeing and managing an organization's IT infrastructure, which includes networks, servers, storage, and related systems. They ensure that all technology systems operate efficiently, securely, and support business goals. Their duties often involve leading a team of IT professionals, planning and implementing infrastructure projects, and troubleshooting complex technical issues. IT Infrastructure Leads also play a key role in maintaining system reliability, disaster recovery planning, and integrating new technologies.

What are the key skills and qualifications needed to thrive as an IT Infrastructure Lead?

To thrive as an IT Infrastructure Lead, you need deep expertise in network design, server management, cybersecurity, and typically hold a degree in computer science or a related field. Familiarity with tools like VMware, Cisco systems, cloud platforms (e.g., AWS or Azure), and certifications such as CCNP or ITIL are commonly required. Strong leadership, problem-solving, and communication skills are essential for coordinating teams and managing complex projects. These competencies ensure reliable, secure, and scalable IT environments that support organizational goals.

What are some common challenges faced by an IT Infrastructure Lead, and how can they be addressed?

IT Infrastructure Leads often encounter challenges such as managing diverse technology stacks, ensuring system reliability, and coordinating across multiple teams. Balancing ongoing maintenance with the implementation of new technologies requires strong organizational and prioritization skills. Effective communication and collaboration with stakeholders, such as network engineers, security teams, and business managers, are crucial to align infrastructure initiatives with company goals. Continuous learning and adapting to emerging technologies also help address these challenges and keep infrastructure resilient and scalable.

What is the difference between It Infrastructure Lead vs Network Engineer?

AspectIt Infrastructure LeadNetwork Engineer
CertificationsITIL, CompTIA Network+, Cisco CCNACCNA, CCNP, CompTIA Network+
Work EnvironmentOversees entire IT infrastructure, including servers, storage, and networksFocuses primarily on designing, implementing, and maintaining network systems
Employer & Industry UsageUsed in organizations managing large IT infrastructure projectsCommon in companies with complex network needs
Search & Comparison IntentOften compared for leadership roles in IT infrastructureCompared for specialized network roles

The It Infrastructure Lead oversees the entire IT infrastructure, including networks, servers, and storage, often managing teams and strategic planning. In contrast, a Network Engineer specializes in designing, implementing, and maintaining network systems. While both roles require networking certifications like CCNA, the Lead has broader responsibilities across the entire IT environment, making it a more senior and strategic position.

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It Infrastructure Lead jobs near you
Infographic showing various It Infrastructure Lead job openings in the United States as of August 2026, with employment types broken down into 89% Full Time, 9% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $137,929 per year, or $66.3 per hour.

Associate Director, IT Infrastructure and Security

Scorpion Therapeutics

Boston, MA • On-site

$180 - $220/hr

Other

Posted 6 days ago

Job description

Responsibilities
  • Oversee Microsoft 365 (IAM, Intune, Microsoft Defender, Purview).
  • Ensure secure endpoint configuration and management with MSP and Security Operations Center for corporate devices and BYOD.
  • Architect and scale enterprise infrastructure and cloud computing environments to support growth.
  • Lead data governance efforts (DLP, sensitivity labels, AI security policies).
  • Advance the Information Security program aligned with SOX, GxP, FDA and other relevant regulatory requirements.
  • Work with MSPs to manage web infrastructure (web hosting, DNS, Cloudflare, GitHub).
  • Architect and support cloud-based DevOps environment.
  • Ensure robust and secure home office technology infrastructure.
  • Lead implementation and ongoing optimization of cloud-based applications and infrastructure.
  • Ensure infrastructure solutions comply with corporate policies/standards and relevant regulations.
Requirements
  • Bachelor’s degree in IT, computer science, engineering, or related field; equivalent experience considered.
  • 10+ years progressive IT experience in regulated life sciences/biotech/pharmaceutical environments.
  • Experience supporting cloud infrastructure, digital workplace technologies, business systems, and cybersecurity controls.
  • Experience managing MSPs, vendors, and third-party partners.
  • Working knowledge of SOX, GxP, FDA-regulated environments, and NIST CSF.
  • Expertise in Microsoft Azure, cloud architecture, and modern IT infrastructure.
  • Familiarity with AI-enabled workplace tools and governance.
  • Exceptional problem-solving; willing to provide hands‑on technical support.
  • Excellent communication and interpersonal skills.

Salary range: $180,000–$220,000 USD.

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