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Integrated Proteins Jobs (NOW HIRING)

Mount Sinai Hospital

Postdoctoral Fellow-MSH

Manhattan, NY · On-site

$53K - $73K/yr

The laboratory generates, analyzes, and integrates high-throughput fluorescence imaging, molecular biology and biochemistry to determine the mechanism of RNA binding proteins in cells (e.g., iPSCs ...

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Integrated Proteins information

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$11K

$92.5K

$146.5K

How much do integrated proteins jobs pay per year?

As of Aug 20, 2026, the average yearly pay for integrated proteins in the United States is $92,500.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,000.00 and $135,000.00 per year, depending on experience, location, and employer.

What are integrated proteins?

Integrated proteins, also known as integral membrane proteins, are proteins that are permanently attached to the cell membrane. They play crucial roles in various cellular processes, such as transporting molecules across the membrane, cell signaling, and maintaining the structure of the cell. These proteins span the lipid bilayer and can interact with both the interior and exterior environments of the cell. Their functions are essential for cell communication and homeostasis.

What are the key skills and qualifications needed to thrive as an integrated proteins scientist, and why are they important?

To thrive as an Integrated Proteins Scientist, you need a strong background in biochemistry, molecular biology, and protein engineering, typically supported by an advanced degree in a life sciences field. Familiarity with laboratory techniques such as mass spectrometry, chromatography, and bioinformatics tools, as well as experience using LIMS and relevant data analysis software, is essential. Strong analytical thinking, attention to detail, and effective communication skills help you collaborate across multidisciplinary teams and interpret complex data. These skills are crucial for driving innovation, ensuring accurate results, and advancing protein research and development.

What are some common challenges faced by professionals working in integrated proteins roles, and how can they be addressed?

Professionals in integrated proteins roles often encounter challenges such as coordinating across interdisciplinary teams, staying updated with rapidly advancing technologies, and managing complex data from various sources. To address these, it is essential to develop strong communication skills, foster collaborative relationships with colleagues in research, production, and quality control, and actively pursue continuous learning through training and industry seminars. Additionally, leveraging project management tools and bioinformatics software can help streamline workflows and ensure data integrity.
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Integrated Proteins jobs near you
Infographic showing various Integrated Proteins job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 9% Part Time, and 4% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $92,500 per year, or $44.5 per hour.

Principal Scientist - Bioseparation & Analytical Development

Element Materials Technology

Ann Arbor, MI • On-site

Other

Re-posted 15 days ago

Element Materials Technology rating

7.3

Company rating: 7.3 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

75th of 120 rated laboratories

Job description

Overview
Element Ann Arbor is currently seeking a highly experienced Principal Scientist - Bioseparation to lead and execute advanced analytical method development, characterization, and validation of large molecule therapeutics across discovery, development, and late-stage CMC. This is an onsite, laboratory-based role with significant hands-on responsibility in bioseparation sciences, supporting a broad range of biologics modalities including proteins and recombinant proteins, peptides and peptide-drug conjugates, monoclonal antibodies (mAbs) and biosimilars, antibody-drug conjugates (ADCs), mRNA therapeutics, DNA constructs (including plasmid DNA and oligonucleotides), viral vectors, and other complex or emerging modalities such as fusion proteins, multispecifics, and engineered biologics.
Responsibilities
  • Lead development, optimization, and troubleshooting of bioseparation-based analytical methods supporting biologics across discovery, development, and late-stage CMC, including orthogonal analytical strategies for comprehensive characterization
  • Perform hands-on execution and technical leadership across a broad range of modalities, including proteins and recombinant proteins, peptides and peptide-drug conjugates, monoclonal antibodies (mAbs) and biosimilars, antibody-drug conjugates (ADCs), mRNA therapeutics, DNA/plasmid DNA/oligonucleotides, viral vectors, and emerging complex biologics (fusion proteins, multispecifics, engineered constructs)
  • Apply deep expertise in chromatography platforms (HPLC/UPLC/UHPLC, SEC, IEX, HIC, RP-HPLC, affinity chromatography), mass spectrometry (LC-MS/MS, high-resolution MS, SEC-MALS, native MS, MAM workflows, glycan/PTM characterization), capillary electrophoresis (CE-SDS, cIEF, purity/identity assays), and supporting biophysical techniques (DLS, DSC, UV/fluorescence, MALS, CD, FTIR)
  • Lead analytical strategy for complex biologics programs, including method development, qualification, validation, transfer, comparability, stability, forced degradation, and full characterization studies
  • Ensure development of robust GMP-compliant methods aligned with ICH Q2/Q6, USP, EP, and GMP requirements, and support regulatory submissions (IND, BLA, IMPD) with high-quality analytical data packages
  • Drive innovation in analytical science, including implementation of MAM workflows, high-throughput LC-MS platforms, automated bioseparation methods, and evaluation of emerging technologies in biologics characterization
  • Provide scientific leadership and mentorship to junior scientists, including troubleshooting complex bioseparation and mass spectrometry challenges and establishing best practices in analytical development and execution

Skills / Qualifications
  • BS in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field required; Master's degree or higher preferred, but not required.
  • Extensive industry experience in biologics analytical development is highly desirable
  • 8-15+ years of experience in biopharmaceutical or CRO analytical development with strong hands-on expertise in bioseparation of large molecules
  • Deep technical expertise across analytical platforms, including LC/UPLC/SEC/IEX/HIC/RP chromatography, LC-MS and high-resolution mass spectrometry, CE-SDS, cIEF, SEC-MALS, and complementary biophysical techniques
    Strong scientific knowledge of protein structure and higher-order structure, monoclonal antibodies and biosimilars, antibody-drug conjugates (ADCs), engineered biologics, and nucleic acid-based therapeutics (mRNA, DNA, oligonucleotides)
  • Demonstrated experience in comparability, stability studies, and degradation pathway analysis for complex biologics
  • Preferred experience includes CRO or client-facing analytical project execution, MAM workflows, advanced LC-MS analytics, glycan mapping and PTM quantification, and automation/high-throughput analytical systems
  • Strong scientific writing capability with experience supporting regulatory documentation and submissions
  • Proven ability to execute in onsite laboratory environments with strong hands-on bioseparation and multi-platform analytical integration skills
  • Ability to manage complex biologics programs in fast-paced, matrixed environments with strong problem-solving and scientific reasoning capabilities
  • Effective communicator across scientific, regulatory, and operational stakeholders

Physical Demands:
  • Frequency of required physical force: Minimum (moderate)
  • Lifting requirements: lifting <50 lbs. often and >50 lbs. on occasion
  • Ability to stand on feet for long periods of time
  • Ability to lift 50+lbs periodically

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Diversity Statement
At Element, we always take pride in putting our people first. We are an equal opportunity employer that recognizes diversity and inclusion as fundamental to our Vision of becoming "the world's most trusted testing partner".
All suitably qualified candidates will receive consideration for employment on the basis of objective work related criteria and without regard for the following: age, disability, ethnic origin, gender, marital status, race, religion, responsibility of dependents, sexual orientation, or gender identity or other characteristics in accordance with the applicable governing laws or other characteristics in accordance with the applicable governing laws.

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