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In Situ Hybridization Jobs (NOW HIRING)

KA Recruiting Inc.

Histotechnologist

Buffalo, NY · On-site

Process and prepare fixed and unfixed tissue and cytology specimens using histologic, frozen sectioning, immunohistochemical, in situ hybridization, and tissue microarray techniques. * Competitive ...

Caris Life Sciences

Oncologic Pathologist

Phoenix, AZ · On-site

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

Caris Life Sciences

Oncologic Pathologist

Phoenix, AZ · On-site

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

Bio-Techne

$83K - $137K/yr

Our ideal candidate will have strong hands-on technical skills, knowledge of immunohistochemistry (IHC), immunofluorescence (IF), in-situ hybridization, spatial biology, and other tissue biomarker ...

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In Situ Hybridization information

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How much do in situ hybridization jobs pay per hour?

As of Jul 25, 2026, the average hourly pay for in situ hybridization in the United States is $22.51, according to ZipRecruiter salary data. Most workers in this role earn between $18.51 and $24.04 per hour, depending on experience, location, and employer.

What is the difference between In Situ Hybridization vs Cytogenetic Technologist?

AspectIn Situ HybridizationCytogenetic Technologist
Required CredentialsTypically requires a bachelor's degree in biology, molecular biology, or related field; certification may be preferredRequires a bachelor's degree in biology, genetics, or related field; certification often recommended
Work EnvironmentLaboratory settings focusing on molecular and cellular analysisLaboratories performing chromosome analysis and genetic testing
Industry UsageUsed in research, diagnostics, and pathology labs for detecting nucleic acid sequencesUsed in clinical genetics labs for karyotyping and genetic diagnosis

In Situ Hybridization and Cytogenetic Technologists both work in laboratory settings within the genetics and molecular biology fields. While In Situ Hybridization focuses on detecting specific nucleic acid sequences within cells, Cytogenetic Technologists analyze chromosomes for genetic abnormalities. Both roles require similar educational backgrounds and are essential in genetic diagnostics, but they specialize in different techniques and analysis methods.

What are the key skills and qualifications needed to thrive as an In Situ Hybridization Specialist, and why are they important?

To thrive as an In Situ Hybridization Specialist, you need a solid background in molecular biology, histology, and laboratory techniques, usually supported by a degree in a biological science. Proficiency in using laboratory instruments such as microtomes, microscopes, and imaging systems, as well as familiarity with protocols like FISH and RNAscope, is essential. Attention to detail, problem-solving skills, and effective communication are valuable soft skills that enhance accuracy and collaboration. These qualifications ensure precise experimental results, reliable data interpretation, and successful teamwork in research or diagnostic settings.

What are some common challenges faced by professionals working in In Situ Hybridization (ISH), and how can they be addressed?

Professionals working in In Situ Hybridization often encounter challenges such as optimizing probe specificity, minimizing background staining, and maintaining sample integrity. These issues can affect the clarity and reliability of results. Addressing them typically involves rigorous protocol optimization, careful reagent selection, and thorough troubleshooting. Additionally, collaboration with pathologists, molecular biologists, and lab technicians is crucial for interpreting results and refining techniques. Continuous training and staying updated on new ISH methodologies can further help overcome these challenges.

What is in situ hybridization?

In situ hybridization (ISH) is a laboratory technique used to detect specific nucleic acid sequences (DNA or RNA) within fixed tissues or cells. This method uses labeled probes that bind to complementary sequences, allowing researchers to visualize the location, abundance, and distribution of target genes or transcripts directly in their cellular context. ISH is widely used in research and diagnostics to study gene expression patterns, identify genetic abnormalities, and investigate infectious agents in tissue samples.
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In Situ Hybridization jobs near you
Infographic showing various In Situ Hybridization job openings in the United States as of July 2026, with employment types broken down into 15% Locum Tenens, 7% Internship, 48% Temporary, 29% Nights, and 1% Summer. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $46,828 per year, or $22.5 per hour.
Faculty Position - Department of Pathology, Comparative Pathologist

Faculty Position - Department of Pathology, Comparative Pathologist

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 25 days ago

St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

37th of 1,023 rated hospitals

Job description

SJCRH
Assistant/Associate/Full Professor of Comparative Pathology
Comparative Pathology Core, Department of Pathology
St. Jude Children's Research Hospital is seeking a Comparative Pathologist for a faculty position in the Division of Comparative Pathology, Department of Pathology. This is an exceptional opportunity to join a highly collaborative research environment and partner with world-class scientists advancing discovery in oncology, hematology, immunology, neuroscience, and infectious disease.
The successful candidate will contribute deep expertise in translational and comparative pathobiology, histopathology, and quantitative pathology while helping shape innovative preclinical research programs and the development of novel therapeutic strategies. Academic rank at the assistant, associate, or full professor level will be commensurate with the candidate's qualifications and experience. The search committee will begin reviewing applications immediately.
INSTITUTION: St. Jude Children's Research Hospital is internationally recognized for pioneering research in pediatric cancer and other catastrophic diseases and offers a uniquely collaborative environment for translational discovery. The Division of Comparative Pathology manages the Comparative Pathology Core (CPC), which is one of many shared resources established by St. Jude to support all research programs on campus. These shared resources are equipped with sophisticated instrumentation not readily available to individual laboratories and are staffed by experts that make cutting-edge technologies accessible and affordable to investigators. The CPC provides investigators utilizing preclinical models with access to clinical pathology (hematology, clinical chemistry, serology, bacteriology, and molecular diagnostics) and anatomic pathology (collection, processing, staining, and evaluation of tissues) services. This position offers the opportunity to contribute as both a scientific collaborator and faculty member in a research-intensive academic setting.
RESPONSIBILITIES:
  • Conduct histopathologic, immunohistochemical, in situ hybridization, and morphometric evaluations of tissue samples from preclinical basic and translational research studies spanning diverse fields such as oncology, hematology, immunology, neuroscience, and infectious disease.
  • Advise investigators on the effective application of microscopy, immunohistochemistry, immunofluorescence, in situ hybridization, and digital pathology/image analysis to elucidate disease mechanisms.
  • Integrate findings across experimental systems and species to explain disease pathophysiology in animal models and interpret the translational relevance of comparative pathology observations.
  • Develop, troubleshoot, and standardize multiplex in situ hybridization and immunohistochemistry protocols for novel targets and biomarkers.
  • Coordinate with research investigators, pathology colleagues, and specialized shared resources, including the Center for Spatial Omics, the Cell and Tissue Imaging Center, and the Center for In Vivo Imaging and Therapeutics, to advance collaborative projects.
  • Contribute to the scientific literature through publication of collaborative research findings and case reports in peer-reviewed journals.

QUALIFICATIONS
  • Required: DVM/VMD or an equivalent degree; board certification in anatomic pathology by the American College of Veterinary Pathologists or the European College of Veterinary Pathologists; exceptional interpersonal, technical, written, and verbal communication skills; and a demonstrated ability to work effectively in collaborative, multidisciplinary teams.
  • Preferred: Training and experience in comparative pathology, proficiency with digital pathology and image analysis tools, and a discovery-oriented approach to collaborative research. The ideal candidate will be an enthusiastic communicator and scientific partner who can exercise independent judgment in recommending and implementing optimal methods to support St. Jude investigators.

APPLICATION INFORMATION: Applications should be submitted directly online as a single PDF document and must include: a cover letter describing the applicant's experience in anatomic pathology, a detailed curriculum vitae, and the names and contact information for three professional references from whom letters of reference may be requested.
This position will remain open, and applications will be considered until the position is filled.
For more information/initial inquiries:
Dr. Laura Janke
Director, Division of Comparative Pathology
St. Jude Children's Research Hospital
M/S 250, 262 Danny Thomas Place, Memphis, TN 38105.
(Laura.Janke@STJUDE.ORG)
ST. JUDE IS AN EQUAL OPPORTUNITY EMPLOYER
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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