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In Situ Hybridization Jobs (NOW HIRING)

Tufts University

Computational Biologist

Medford, MA · On-site

$74K - $111K/yr

... in-situ hybridization, and antibody staining. In this role, additional responsibilities include participating in teaching, research, and mentoring including providing research guidance to graduate ...

Caris Life Sciences

Oncologic Pathologist

Phoenix, AZ · On-site

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

KA Recruiting Inc.

Histotechnologist

Buffalo, NY · On-site

Process and prepare fixed and unfixed tissue and cytology specimens using histologic, frozen sectioning, immunohistochemical, in situ hybridization, and tissue microarray techniques. * Competitive ...

Caris Life Sciences

Oncologic Pathologist

Phoenix, AZ · On-site

Provide interpretation of in-situ hybridization (ISH) stains. * Review batch and instrument quality control stains as needed. * Evaluate pathology specimens and render insightful and comprehensive ...

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In Situ Hybridization information

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How much do in situ hybridization jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for in situ hybridization in the United States is $22.51, according to ZipRecruiter salary data. Most workers in this role earn between $18.51 and $24.04 per hour, depending on experience, location, and employer.

What is in situ hybridization?

In situ hybridization (ISH) is a laboratory technique used to detect specific nucleic acid sequences (DNA or RNA) within fixed tissues or cells. This method uses labeled probes that bind to complementary sequences, allowing researchers to visualize the location, abundance, and distribution of target genes or transcripts directly in their cellular context. ISH is widely used in research and diagnostics to study gene expression patterns, identify genetic abnormalities, and investigate infectious agents in tissue samples.

What are the key skills and qualifications needed to thrive as an in situ hybridization specialist?

To thrive as an In Situ Hybridization Specialist, you need a solid background in molecular biology, histology, and laboratory techniques, usually supported by a degree in a biological science. Proficiency in using laboratory instruments such as microtomes, microscopes, and imaging systems, as well as familiarity with protocols like FISH and RNAscope, is essential. Attention to detail, problem-solving skills, and effective communication are valuable soft skills that enhance accuracy and collaboration. These qualifications ensure precise experimental results, reliable data interpretation, and successful teamwork in research or diagnostic settings.

What are some common challenges faced by professionals working in in situ hybridization, and how can they be addressed?

Professionals working in In Situ Hybridization often encounter challenges such as optimizing probe specificity, minimizing background staining, and maintaining sample integrity. These issues can affect the clarity and reliability of results. Addressing them typically involves rigorous protocol optimization, careful reagent selection, and thorough troubleshooting. Additionally, collaboration with pathologists, molecular biologists, and lab technicians is crucial for interpreting results and refining techniques. Continuous training and staying updated on new ISH methodologies can further help overcome these challenges.

What is the difference between In Situ Hybridization vs Cytogenetic Technologist?

AspectIn Situ HybridizationCytogenetic Technologist
Required CredentialsTypically requires a bachelor's degree in biology, molecular biology, or related field; certification may be preferredRequires a bachelor's degree in biology, genetics, or related field; certification often recommended
Work EnvironmentLaboratory settings focusing on molecular and cellular analysisLaboratories performing chromosome analysis and genetic testing
Industry UsageUsed in research, diagnostics, and pathology labs for detecting nucleic acid sequencesUsed in clinical genetics labs for karyotyping and genetic diagnosis

In Situ Hybridization and Cytogenetic Technologists both work in laboratory settings within the genetics and molecular biology fields. While In Situ Hybridization focuses on detecting specific nucleic acid sequences within cells, Cytogenetic Technologists analyze chromosomes for genetic abnormalities. Both roles require similar educational backgrounds and are essential in genetic diagnostics, but they specialize in different techniques and analysis methods.

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In Situ Hybridization jobs near you
Infographic showing various In Situ Hybridization job openings in the United States as of August 2026, with employment types broken down into 94% Full Time, 5% Part Time, and 1% Contract. Highlights an 92% Physical, 4% Hybrid, and 4% Remote job distribution, with an average salary of $46,828 per year, or $22.5 per hour.

Genetics/Genomics Technologist II - 5k Sign On Bonus!

Sonora Quest Laboratories

Phoenix, AZ

Full-time

Re-posted 10 days ago

Sonora Quest Laboratories rating

7.0

Company rating: 7.0 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

84th of 121 rated laboratories

Job description

Primary City/State:
Phoenix, Arizona
Department Name:
Cytogenetic Testing-Ref Lab
Work Shift:
Day
Job Category:
Lab
Experienced in FISH and ready to make an impact? You belong here! Join our growing clinical cytogenetics laboratory as a Genetics/Genomics Technologist II, where your expertise in fluorescence in situ hybridization, complex casework, and advanced cytogenetic testing will help deliver accurate results that guide patient care.
We're currently offering a $5,000 sign on bonus for this role!
POSITION SUMMARY
This position performs genetic/genomic testing in accordance with CAP (College of America Pathologists) standards in an accurate and timely manner. This testing may be complexity and may include:
  • Fluorescence In-Situ Hybridization (FISH)
  • Real-time Polymerase Chain Reaction (PCR)
  • Cytogenetic chromosome analysis
  • Next Generation Sequencing (NGS)
  • Pharmacogenomics (PGx)
  • Chromosomal Microarray (CMA)

Results of these tests, which may have significant clinical impact, are obtained through manual and automated processes. The position serves as an experienced technologist who supports routine casework and lab operations, helping to ensure consistency in day-to-day testing and acting as a resource for newer staff.
Performs all functions according to established policies, procedures, regulatory and accreditation requirements, as well as applicable professional standards.
KNOWLEDGE, SKILLS AND ABILITIES
  • Ability to use good and sound judgment and perform well in supervisor's absence.
  • Ability to work weekends and holidays, as required and/or on rotation.
  • Excellent interpersonal and communication skills.
  • Well developed attention to detail and organization skills.

MINIMUM QUALIFICATIONS
  • Bachelor's degree in medical laboratory science, chemical or biological science, or another accredited four-year degree with equivalent coursework meeting CLIA qualifications for high-complexity testing personnel.
  • Three (3) years' experience as a genetics/genomics technologist.

PREFERRED QUALIFICATIONS
  • ASCP certification in Cytogenetics, Molecular Biology, or Medical Technology.
  • Experience across multiple genetics/genomics technologies
  • Additional related education and/or experience.

EEO Statement:
EEO/Disabled/Veterans
Our organization supports a drug-free work environment.
Privacy Policy:
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