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Flexible Protein Biochemistry Postdoc Jobs (NOW HIRING)

Construction Association of Michigan

$52 - $70/hr

A full-time Postdoctoral Fellow position is available in the Wenjian Gan Lab to investigate the ... The project employs an integrative toolkit combining protein biochemistry, molecular biology ...

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Baylor College of Medicine

WI · On-site

$56.01 - $68.46/hr

Specifically, the postdoc will functionally validate cellular ligands identified through ... Experience in molecular biology, cell biology, protein biochemistry, and/or animal research is ...

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Flexible Protein Biochemistry Postdoc information

What does a flexible protein biochemistry postdoc do?

A Flexible Protein Biochemistry Postdoc is a research scientist who investigates the structure, function, and dynamics of proteins, often with a focus on protein flexibility and conformational changes. They design and conduct experiments using techniques such as X-ray crystallography, NMR spectroscopy, cryo-EM, and computational modeling to understand how protein flexibility impacts biological processes. Their work supports advancements in drug discovery, biotechnology, and fundamental science, often collaborating with multidisciplinary teams.

What are the key skills and qualifications needed to thrive as a flexible protein biochemistry postdoc?

To thrive as a Flexible Protein Biochemistry Postdoc, you need a PhD in biochemistry or a related field, with expertise in protein expression, purification, and characterization. Experience with advanced techniques such as NMR spectroscopy, X-ray crystallography, or mass spectrometry, as well as proficiency in data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective collaboration and communication abilities are essential soft skills. These competencies are crucial for driving innovative research, producing reliable results, and contributing effectively within multidisciplinary scientific teams.

What are some common challenges faced by postdocs in flexible protein biochemistry, and how can they be addressed?

Postdocs in flexible protein biochemistry often encounter challenges such as expressing and purifying dynamic or disordered proteins, which may not behave predictably compared to structured proteins. Additionally, interpreting experimental data from techniques like NMR or cryo-EM, which are sensitive to protein flexibility, can be complex and time-consuming. These challenges can be addressed by collaborating closely with structural biologists, leveraging advanced computational tools, and staying updated on new protocols for handling intrinsically disordered proteins. Regular communication with interdisciplinary teams and attending specialized workshops can also enhance problem-solving and technical skills in this evolving field.
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Flexible Protein Biochemistry Postdoc jobs near you
Infographic showing various Flexible Protein Biochemistry Postdoc job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 67% Full Time, 29% Part Time, and 3% Contract. Highlights an 88% Physical, 1% Hybrid, and 11% Remote job distribution.

Postdoc Research Fellow

American Society for Biochemistry and Molecular Biology (ASBMB)

Cleveland, OH • On-site

$55 - $75/hr

Other

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

A full-time Postdoctoral Fellow position is available in the Wenjian Gan Lab to investigate the mechanistic and physiological roles of protein post-translational modifications (PTMs)-with a focus on arginine methylation in human cancers. Research in the lab explores how arginine methylation regulates genomic instability, cell metabolism, signal transduction, and tumor progression to identify novel druggable targets. The project employs an integrative toolkit combining protein biochemistry, molecular biology, functional cell assays, genetic mouse models, and 3D patient-derived organoids (PDOs).

Key Responsibilities
  • Molecular & Cellular Dissection: Execute biochemical and cell-based experiments (plasmid construction, PCR/RT-qPCR, transfections, IP/Western blot, proliferation, and colony formation assays) to map arginine methylation pathways.
  • In Vivo & Translational Studies: Utilize genetic mouse models and patient-derived organoid platforms to study cancer progression and metastasis, including mouse breeding/genotyping, preclinical drug dosing, and tumor progression tracking.
  • Scientific Communication & Grants: Co-author manuscripts and grant applications with the PI, create publication-ready figures, and present research findings in progress seminars and departmental journal clubs.
  • Lab Stewardship: Contribute to daily laboratory operations, including equipment maintenance, reagent/buffer preparation, inventory management, and lab upkeep.
  • Education & Experience: Ph.D. or M.D./Ph.D. in Biochemistry, Molecular/Cellular Biology, Cancer Biology, or a related discipline.
  • Technical Skills: Proven hands-on expertise in molecular biology, protein biochemistry, cell culture techniques, and mouse models. Experience with organoid culture is preferred.
  • Track Record: Strong background of scientific productivity evidenced by peer-reviewed publications.
  • Professional Attributes: Self-motivated, collaborative, organized, and driven to advance translational cancer research.
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