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Downstream Purification Jobs (NOW HIRING)

Biogen

NC · On-site

$31.25 - $40.87/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

This role's primary focus is Downstream (Purification): * Column Chromatography * Viral Filtration * Ultra-Filtration * Bulk Dispensing of the drug substance What You'll Do * Execute daily ...

Lonza

Biotechnologist I (Nights - A Shift)

Portsmouth, NH · On-site

$17.25 - $21.25/hr

  • Medical

  • Dental

  • Vision

Working in a GMP manufacturing environment, you will operate production equipment, execute downstream purification processes, and ensure products are manufactured safely and to the highest quality ...

Valspec

Process Validation Engineer

Boston, MA

$70 - $80/hr

Upstream (cell culture/bioreactors), Downstream (purification/chromatography), or Clean Utilities (WFI, clean steam, process gases, and supporting utility systems). This person will partner closely ...

Lonza

Biotechnologist I

Portsmouth, NH · On-site

$15.25 - $19.25/hr

  • Medical

  • Dental

  • Vision

Working in a GMP manufacturing environment, you will operate production equipment, execute downstream purification processes, and ensure products are manufactured safely and to the highest quality ...

Lonza

Biotechnologist I (Nights - A Shift)

Portsmouth, NH · On-site

$17.25 - $21.25/hr

  • Medical

  • Dental

  • Vision

Working in a GMP manufacturing environment, you will operate production equipment, execute downstream purification processes, and ensure products are manufactured safely and to the highest quality ...

Lonza

Biotechnologist I (Nights - A Shift)

Portsmouth, NH · On-site

$17.25 - $21.25/hr

  • Medical

  • Dental

  • Vision

Working in a GMP manufacturing environment, you will operate production equipment, execute downstream purification processes, and ensure products are manufactured safely and to the highest quality ...

Valspec

Process Validation Engineer

Rockville, MD

$70 - $80/hr

Upstream (cell culture/bioreactors), Downstream (purification/chromatography), or Clean Utilities (WFI, clean steam, process gases, and supporting utility systems). This person will partner closely ...

Valspec

Process Validation Engineer

Oceanside, CA

$70 - $80/hr

Upstream (cell culture/bioreactors), Downstream (purification/chromatography), or Clean Utilities (WFI, clean steam, process gases, and supporting utility systems). This person will partner closely ...

Valspec

Process Validation Engineer

Raleigh, NC

$70 - $80/hr

Upstream (cell culture/bioreactors), Downstream (purification/chromatography), or Clean Utilities (WFI, clean steam, process gases, and supporting utility systems). This person will partner closely ...

Lonza

Biotechnologist I

Portsmouth, NH · On-site

$15.25 - $19.25/hr

  • Medical

  • Dental

  • Vision

Working in a GMP manufacturing environment, you will operate production equipment, execute downstream purification processes, and ensure products are manufactured safely and to the highest quality ...

Valspec

Process Validation Engineer

Philadelphia, PA

$70 - $80/hr

Upstream (cell culture/bioreactors), Downstream (purification/chromatography), or Clean Utilities (WFI, clean steam, process gases, and supporting utility systems). This person will partner closely ...

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All JobsDownstream Purification Jobs

Downstream Purification information

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$13

$24

$34

How much do downstream purification jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for downstream purification in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in downstream purification, and why are they important?

To excel in Downstream Purification, you need a solid background in biochemistry or chemical engineering, with experience in protein purification techniques and a relevant degree. Familiarity with chromatography systems (e.g., AKTA), filtration technologies, and good manufacturing practice (GMP) certification is highly valuable. Strong analytical thinking, attention to detail, and effective teamwork are important soft skills in this role. These competencies ensure the efficient and reliable production of high-purity biopharmaceutical products, critical for product quality and regulatory compliance.

What are some common challenges faced in a downstream purification role, and how can they be addressed?

Professionals in Downstream Purification often encounter challenges such as maintaining product yield and purity, troubleshooting equipment malfunctions, and adapting to process variability. Addressing these requires strong analytical skills, attention to detail, and close collaboration with upstream teams and quality assurance. Continuous training on the latest purification technologies and strict adherence to standard operating procedures also help minimize errors and improve efficiency in the production process.

What is the difference between Downstream Purification vs Downstream Processing?

AspectDownstream PurificationDownstream Processing
FocusPurifying specific products from a mixtureOverall process including purification and initial recovery
CredentialsTypically requires bioprocessing or biotech certificationsSimilar credentials, often overlapping
Work EnvironmentLaboratories, clean rooms, manufacturing facilitiesLabs and production plants
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical, and bioprocessing industries

Downstream Purification is a specialized part of the broader Downstream Processing. While downstream processing includes all steps from initial product recovery to purification, downstream purification specifically focuses on isolating and purifying the target product. Both roles often require similar skills and certifications, and they operate in comparable environments within biotech and pharmaceutical industries.

More about Downstream Purification jobs

What cities are hiring for Downstream Purification jobs?

Cities with the most Downstream Purification job openings:

What states have the most Downstream Purification jobs?

States with the most job openings for Downstream Purification jobs include:

What job categories do people searching Downstream Purification jobs look for?

The top searched job categories for Downstream Purification jobs are:

Downstream Purification jobs near you
Infographic showing various Downstream Purification job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 1% Part Time, 6% Contract, and 1% Nights. Highlights an 83% Physical, 5% Hybrid, and 12% Remote job distribution, with an average salary of $51,890 per year, or $24.9 per hour.

Associate Scientist, Purification Process Design

Just - Evotec Biologics

Seattle, WA • On-site

$78K - $82K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 6 days ago

Job description

Job Title: Associate Scientist
Location: Seattle, WA
Department: Purification Process Design
Reports To: Scientist II
About Us:
At Just-Evotec, we believe that curiosity is the spark that drives innovation and success. As a forward-thinking team, we thrive on challenging the status quo, learning from each other, and pushing the boundaries of what's possible. We're on a mission to create a place where curiosity isn't just encouraged, it's celebrated.
Are you someone who asks questions, seeks answers, and isn't afraid to go deeper? #BeCureious with us and see where your curiosity can take you!
The Role:
We are seeking a motivated and creative scientist or engineer who desires a significant opportunity to improve worldwide access to biotherapeutics. If you're excited by new challenges, solving complex problems, and learning every step of the way, you might just be the perfect fit. As a member of the downstream process design team, you will join a fast-paced, collaborative, and multidisciplinary team to develop purification processes for low-cost mammalian derived antibody biotherapeutic manufacturing. Process design at Just-Evotec means exposure to innovative technologies like high throughput automated robotic screening and continuous processing technologies for a first-of-its-kind flexible and reconfigurable manufacturing facility. In this role, you'll have the opportunity to drive impactful projects, collaborate with bright minds, and explore uncharted territories.
As an Associate Scientist at Just-Evotec, you'll have the freedom to ask the hard questions, think outside the box, and find creative solutions that push us forward. It's a role where your curiosity will fuel both your personal growth and the success of the team.
What You'll Do:
  • Dive deep into purification process development for biotherapeutics, always looking for ways to improve and innovate.
  • Accurately and consistently record laboratory work in electronic lab notebooks and paper batch records
  • Compound purification buffers and solutions, assemble and pack chromatography column hardware
  • Operate AKTA Avant & Pure systems using Unicorn software, Pendotech four-channel NFF automated data collection systems, TECAN high throughput liquid handlers, and Repligen automated TFF systems
  • Analytical results analysis from chromatography and filtration operations, organization and presentation of data, and report writing
  • Support the transfer processes to manufacturing facilities
  • Technology development to expand platform capabilities, reduce cost, and improve the efficiency of purification processes
  • Regularly share your findings, ideas, and solutions in both team settings and presentations.

Who You Are:
  • A curious problem-solver with a passion for learning and growing in a dynamic environment.
  • BS/BA degree in Engineering, Biochemistry, Biotechnology or related field and 0 -2 years of relevant laboratory experience
  • Excellent experimental design and analysis skills, ideally including manipulation and presentation using JMP or equivalent statistical analysis software
  • Experience with chromatography operations including using AKTA systems
  • Familiar with mammalian derived downstream purification development, resin modalities (affinity, IEX, MM, HIC) and chromatography purification theory
  • Experience with filtration operation including executing bench-scale dead-end filtration, viral filtration, UF/DF, and depth filtration
  • Experience with design of experiments (DOE) and analysis using statistical software packages
  • Excellent communicator, both verbally and in writing, able to share complex ideas in a simple, relatable way.

Why Join Us:
  • Growth Opportunities: We're a company that believes in continuous learning and development. Whether it's professional courses, mentorship, or new projects, we'll help you grow.
  • Inclusive Culture: We're committed to building a diverse and inclusive environment where everyone's voice is valued, and curiosity is encouraged.
  • Innovative Projects: You'll have the chance to work on groundbreaking initiatives and cutting-edge technology in an atmosphere where your curiosity is the key to success.
  • A Place for Big Ideas: We don't just talk about thinking outside the box-we throw the box away. If you've got ideas, we want to hear them.

Are You Still Curious?
If you've read this far, then chances are you've got a curious mind, just like us. So, what are you waiting for? Take the leap and apply today. We can't wait to see where your curiosity leads you and how it will shape the future of Just-Evotec Biologics.
Let your curiosity guide your career #BeCUREious and explore the endless possibilities at Just-Evotec!
The base pay range for this position at commencement of employment is expected to be $78,000 to $82,000; Base salary offered may vary depending on individual's skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.
Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

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