ZipRecruiter

Log In

1

Downstream Purification Jobs (NOW HIRING)

Managed Staffing

Purification Scientist

Boston, MA · On-site

$44 - $46/hr

Monday-Friday | 8:00 AM-5:00 PM (40 hrs/week Position Summary Seeking an early-career Biologist / Purification Scientist to join the Downstream Process Development team in Boston, MA. This role will ...

next page

Showing results 1-20

All JobsDownstream Purification Jobs

Downstream Purification information

See salary details

$13

$24

$34

How much do downstream purification jobs pay per hour?

As of Jun 27, 2026, the average hourly pay for downstream purification in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What is downstream purification?

Downstream purification refers to the series of processes used to isolate and purify a target product, such as a protein or antibody, from a complex mixture after it has been produced by cells or microorganisms. This is a critical step in biotechnology and pharmaceutical manufacturing, involving techniques like filtration, chromatography, and centrifugation to remove impurities and contaminants. The goal is to achieve a high level of purity and quality for the final product, ensuring it meets regulatory standards for use in research, diagnostics, or therapeutics.

What are the key skills and qualifications needed to thrive in Downstream Purification, and why are they important?

To excel in Downstream Purification, you need a solid background in biochemistry or chemical engineering, with experience in protein purification techniques and a relevant degree. Familiarity with chromatography systems (e.g., AKTA), filtration technologies, and good manufacturing practice (GMP) certification is highly valuable. Strong analytical thinking, attention to detail, and effective teamwork are important soft skills in this role. These competencies ensure the efficient and reliable production of high-purity biopharmaceutical products, critical for product quality and regulatory compliance.

What are some common challenges faced in a Downstream Purification role, and how can they be addressed?

Professionals in Downstream Purification often encounter challenges such as maintaining product yield and purity, troubleshooting equipment malfunctions, and adapting to process variability. Addressing these requires strong analytical skills, attention to detail, and close collaboration with upstream teams and quality assurance. Continuous training on the latest purification technologies and strict adherence to standard operating procedures also help minimize errors and improve efficiency in the production process.

What is the difference between Downstream Purification vs Downstream Processing?

AspectDownstream PurificationDownstream Processing
FocusPurifying specific products from a mixtureOverall process including purification and initial recovery
CredentialsTypically requires bioprocessing or biotech certificationsSimilar credentials, often overlapping
Work EnvironmentLaboratories, clean rooms, manufacturing facilitiesLabs and production plants
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical, and bioprocessing industries

Downstream Purification is a specialized part of the broader Downstream Processing. While downstream processing includes all steps from initial product recovery to purification, downstream purification specifically focuses on isolating and purifying the target product. Both roles often require similar skills and certifications, and they operate in comparable environments within biotech and pharmaceutical industries.

More about Downstream Purification jobs
What cities are hiring for Downstream Purification jobs? Cities with the most Downstream Purification job openings:
What states have the most Downstream Purification jobs? States with the most job openings for Downstream Purification jobs include:
What job categories do people searching Downstream Purification jobs look for? The top searched job categories for Downstream Purification jobs are:
Downstream Purification jobs near you
Infographic showing various Downstream Purification job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $51,890 per year, or $24.9 per hour.
Associate Lab Support Technician, Biopharma(JP9489)

Associate Lab Support Technician, Biopharma(JP9489)

3 Key Consulting

Thousand Oaks, CA

$19 - $21/hr

Other

Posted 17 days ago

Job description

Job Title:Associate Lab Support Technician, Biopharma(JP9489)
Location:Thousand Oaks, CA
Employment Type: Contract
Duration: Initial 6 months possible extensions or conversion to FTE
Job posting date: 12/2/2021
Rate: $19-21/Hr
Target start Date: 1/3/2022
Note:Onsite Essential.Must be able to work multiple shifts at 3 month intervals (Day and swing shift)
3 Key Consulting is hiring anAssociate Lab Support Technicianfor a consulting engagement with our direct client, a leading global bio-pharmaceutical company.
Job Description:
Under general supervision, supports the execution of harvest and downstream purification process studies using pilot scale equipment including chromatography skids and filtration systems. Routine tasks include equipment preparation, operating chromatography and filtration systems, compounding media and buffer solutions, and sampling. Utilizes scientific principles in execution of experiments and analysis of experimental data. Carries out laboratory tasks per plan and procedure in a team environment. Documents data and process information in accordance to good documentation practices. Performs laboratory safety evaluations. Organizes and stocks laboratory supplies. Executes process/equipment troubleshooting. Performs in-process testing using laboratory analyzers.
Basic Qualifications:
Bachelors degree in Engineering or Science. Ability to work evening/nights and occasional weekend work. Evening/Night work is scheduled on a fixed duration rotation, subject to change.
Preferred Qualifications:
Prior hands-on experience in pilot-scale or large-scale cell culture or downstream purification process development or manufacturing operation. Experience with automated and computer-controlled biopharmaceutical process equipment. Knowledge of process data compilation and analysis. Demonstrated equipment troubleshooting skills. Excellent problem-solving capabilities and attention to detail. Experience of collaboration within and across functional areas and outstanding customer focus. Excellent written and verbal communication skills.
Top Must have Skill Sets:
  • Chromatography Experience - At least 1 year experience preferred
  • Biotech Process Development or Manufacturing experience.
  • Large Scale processing, buffer prep or media prep experience.
  • Must be able to work multiple shifts at 3 month intervals (Day and swing shift)

Employee Value Proposition:
The person in this role will do hands on bio processing using large scale purification equipment and managing purification samples.
Red Flags:
A candidate with an advanced degree may not fit well in this role (Masters degree or doctorate degree)
Interview Process:
Interview process will be a phone screen by hiring manager and possibly 1-2 other managers followed by a face-to-face interview with hiring manager and 1-2 other managers. Early morning or late afternoon.
We invite qualified candidates to sendyour resume toresumes@3keyconsulting.com. Ifyou decide that you're not interested in pursuing this position, please feel free to look at other positions on our websitewww.3keyconsulting.com. You are welcome to also sharethis posting withanyone you think might be interested in applying for this role.

Apply