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Downstream Purification Jobs (NOW HIRING)

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Downstream Purification information

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$34

How much do downstream purification jobs pay per hour?

As of May 31, 2026, the average hourly pay for downstream purification in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in Downstream Purification, and why are they important?

To excel in Downstream Purification, you need a solid background in biochemistry or chemical engineering, with experience in protein purification techniques and a relevant degree. Familiarity with chromatography systems (e.g., AKTA), filtration technologies, and good manufacturing practice (GMP) certification is highly valuable. Strong analytical thinking, attention to detail, and effective teamwork are important soft skills in this role. These competencies ensure the efficient and reliable production of high-purity biopharmaceutical products, critical for product quality and regulatory compliance.

What are some common challenges faced in a Downstream Purification role, and how can they be addressed?

Professionals in Downstream Purification often encounter challenges such as maintaining product yield and purity, troubleshooting equipment malfunctions, and adapting to process variability. Addressing these requires strong analytical skills, attention to detail, and close collaboration with upstream teams and quality assurance. Continuous training on the latest purification technologies and strict adherence to standard operating procedures also help minimize errors and improve efficiency in the production process.

What is downstream purification?

Downstream purification refers to the series of processes used to isolate and purify a target product, such as a protein or antibody, from a complex mixture after it has been produced by cells or microorganisms. This is a critical step in biotechnology and pharmaceutical manufacturing, involving techniques like filtration, chromatography, and centrifugation to remove impurities and contaminants. The goal is to achieve a high level of purity and quality for the final product, ensuring it meets regulatory standards for use in research, diagnostics, or therapeutics.

What is the difference between Downstream Purification vs Downstream Processing?

AspectDownstream PurificationDownstream Processing
FocusPurifying specific products from a mixtureOverall process including purification and initial recovery
CredentialsTypically requires bioprocessing or biotech certificationsSimilar credentials, often overlapping
Work EnvironmentLaboratories, clean rooms, manufacturing facilitiesLabs and production plants
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical, and bioprocessing industries

Downstream Purification is a specialized part of the broader Downstream Processing. While downstream processing includes all steps from initial product recovery to purification, downstream purification specifically focuses on isolating and purifying the target product. Both roles often require similar skills and certifications, and they operate in comparable environments within biotech and pharmaceutical industries.

More about Downstream Purification jobs
What cities are hiring for Downstream Purification jobs? Cities with the most Downstream Purification job openings:
What states have the most Downstream Purification jobs? States with the most job openings for Downstream Purification jobs include:
Infographic showing various Downstream Purification job openings in the United States as of May 2026, with employment types broken down into 82% Full Time, 12% Part Time, 1% Temporary, and 5% Contract. Highlights an 57% Physical, 10% Hybrid, and 33% Remote job distribution, with an average salary of $51,890 per year, or $24.9 per hour.
Associate Scientist - Downstream

Associate Scientist - Downstream

Avantor Inc.

Bridgewater, NJ

$69K - $110.98K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 11 days ago


Avantor rating

8.1

Company rating: 8.1 out of 10

Based on 59 frontline employees who took The Breakroom Quiz

35th of 89 rated chemical manufacturers


Job description

The Opportunity:Avantor is seeking an Associate Scientist - Downstream for the Bridgewater, NJ location.

The Associate Scientist - Downstream will be responsible for the hands-on execution of laboratory experiments for the protein purification process and contribute to the development and optimization of processes.

The main responsibilities will include:

  • Executes and supports downstream purification (e.g. monoclonal antibodies, fusion proteins, etc.) on a bench-scale jointly with other scientists or independently.

  • Conducts pilot-scale material generations with the team.

  • Prepares and executes experimental protocols and analytical test methods under general guidance.

  • Accurately documents all procedures and observations

  • Maintains laboratory area, utilizes safe practices while working in the laboratory environment as per EHS guidelines and policy.

    What we're looking for:

    • Education: Bachelor's degree in Biochemistry, Biotechnology, or a related scientific field.

    • Experience: Hands-on experience with protein purification techniques and downstream processing preferred.

    • Familiarity with Good Laboratory Practices (GLP) and laboratory safety standards.

    Who you are:

    • Strong background in molecular biology, biochemistry, or bioengineering.

    • Strong communication skills

    • Perform duties with the highest regard for safety and quality

    • Ability to understand and follow scientific protocols, policies and procedures

    • Must be flexible, forward-thinking, and motivated

    • Able to act independently and manage responsibilities while following scientific direction

    • Must be able to lift 25lbs minimum

    • Basic computing skills, including Microsoft Office Suite (or equivalent)

    • Skilled at prioritizing tasks, problem solving, and meeting deadlines

    • Strong analytical, organizational, and communication skills.

    • Ability to work both independently and as part of a collaborative team

    How you will thrive and create and impact:

    • Downstream Process Execution: Perform bench-scale purification of biologics, such as monoclonal antibodies, bispecific, fusion proteins, or AAV, independently or in collaboration with other scientists. Support pilot-scale material generation and assist in technology transfer activities.

    • Experimental Design & Implementation: Prepare and execute experimental protocols and analytical methods under general guidance. Contribute to the development and optimization of downstream processes.

    • Technical Problem Solving:Identify and resolve process development challenges through data-driven experimentation and innovative thinking.

    • Data Interpretation & Reporting: Analyze, interpret, and summarize experimental data. Present findings clearly in team meetings and contribute to project decision-making.

    • Laboratory Operations: Operate, maintain, and troubleshoot laboratory instruments in accordance with SOPs. Ensure accurate documentation of procedures and observations.

    • Product Evaluation:Assess Avantor's technologies-such as chromatographic resins, process additives, and single-use technologies-for their effectiveness in biologics purification workflows.

    • Compliance:Ensure all activities comply with safety, environmental, and quality standards and best practices.

    Disclaimer:

    The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Avantor is proud to be an equal opportunity employer.

    Why Avantor?

    Dare to go further in your career. Join our global team of 14,000+ associates whose passion for discovery and determination to overcome challenges relentlessly advances life-changing science.
    The work we do changes people's lives for the better. It brings new patient treatments and therapies to market, giving a cancer survivor the chance to walk his daughter down the aisle. It enables medical devices that help a little boy hear his mom's voice for the first time. Outcomes such as these create unlimited opportunities for you to contribute your talents, learn new skills and grow your career at Avantor.
    We are committed to helping you on this journey through our diverse, equitable and inclusive culture which includes learning experiences to support your career growth and success. At Avantor, dare to go further and see how the impact of your contributions set science in motion to create a better world. Apply today!

    Pay Transparency:

    The expected pre-tax pay for this position is

    $69,000.00 - $110,975.00

    Actual pay may differ depending on relevant factors such as prior experience and geographic location.

    EEO Statement:

    We are an Equal Employment/Affirmative Action employer and VEVRAA Federal Contractor. We do not discriminate in hiring on the basis of sex, gender identity, sexual orientation, race, color, religious creed, national origin, physical or mental disability, protected Veteran status, or any other characteristic protected by federal, state/province, or local law.

    If you need a reasonable accommodation for any part of the employment process, please contact us by email at recruiting@avantorsciences.comand let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

    For more information about equal employment opportunity protections, please view the Know Your Rights poster.

    Privacy Policy:

    We will use the personal information that you have submitted to us in order to consider your application for the relevant role.

    Your privacy is important to us. Please click here for our Privacy Policy which explains the purposes for which we will use your personal information and the ways in which we will handle and retain your information. It also explains the rights you have in relation to your information, and how to contact us with any queries or requests.

    3rd Party Non-Solicitation Policy:

    By submitting candidates without having been formally assigned on and contracted for a specific job requisition by Avantor, or by failing to comply with the Avantor recruitment process, you forfeit any fee on the submitted candidates, regardless of your usual terms and conditions. Avantor works with a preferred supplier list and will take the initiative to engage with recruitment agencies based on its needs and will not be accepting any form of solicitation.

    Avantor offers a comprehensive benefits package including medical, dental, and vision coverage, wellness programs, health savings and flexible spending accounts, a 401(k) plan with company match, and an employee stock purchase program. Employees also receive 11 paid holidays, accrue 18 PTO days annually, are eligible for volunteer time off and 6 weeks of 100% paid parental leave (except in states that offer paid family leave). These benefits may not apply to employees covered by a collective bargaining agreement or those subject to other eligibility rules.


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    About Avantor

    Sourced by ZipRecruiter

    At Avantor, our ICARE Values are our core set of principles that guide and focus the Company's strategy.: Innovation; customer centric; accountability; respect; excellence! Avantor is committed to creating a fully inclusive culture that celebrates diversity and provides equitable opportunities for all associates to grow and succeed. While setting science in motion our employees can join employee focus groups.

    Industry

    Chemical manufacturing

    Company size

    10,000+ Employees

    Headquarters location

    Radnor, PA, US

    Year founded

    1904

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