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Purification Scientist Jobs (NOW HIRING)

Managed Staffing

Purification Scientist

Boston, MA · On-site

$44 - $46/hr

Biologist - Purification Scientist Client: Eli Lilly and Company Location: Boston, MA (Onsite) Schedule: Monday-Friday | 8:00 AM-5:00 PM (40 hrs/week Position Summary Seeking an early-career ...

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Purification Scientist information

What are the key skills and qualifications needed to thrive as a Purification Scientist, and why are they important?

To thrive as a Purification Scientist, you need a solid understanding of protein chemistry, chromatography techniques, and laboratory best practices, typically supported by a degree in biochemistry, chemistry, or a related field. Familiarity with technical tools such as HPLC, FPLC systems, and analytical software, as well as experience with relevant safety standards, is often required. Strong problem-solving skills, attention to detail, and the ability to work collaboratively are essential soft skills in this role. These qualifications ensure the efficient and accurate purification of biomolecules, which is critical for research, development, and manufacturing in pharmaceutical and biotech industries.

What are some common challenges faced by Purification Scientists, and how can they be addressed on the job?

Purification Scientists often encounter challenges such as optimizing purification protocols for novel proteins, troubleshooting unexpected impurities, and maintaining consistency across large-scale runs. These issues can be addressed by staying up-to-date with the latest chromatography techniques, collaborating closely with upstream and analytical teams, and employing robust troubleshooting and documentation practices. Being proactive in adjusting parameters and communicating effectively with colleagues helps ensure high-quality results and smooth workflow within the team.

What are Purification Scientists?

Purification Scientists are professionals who specialize in isolating and purifying biological or chemical substances, such as proteins, antibodies, or pharmaceuticals, from complex mixtures. They develop, optimize, and scale up purification processes using techniques like chromatography, filtration, and centrifugation. These scientists often work in biotechnology, pharmaceutical, and research laboratories to ensure products are pure, safe, and effective for further research or commercial use.

What is the difference between Purification Scientist vs Analytical Chemist?

AspectPurification ScientistAnalytical Chemist
Required CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fieldBachelor's or Master's in Chemistry, Analytical Chemistry, or related field
Work EnvironmentLaboratories focused on purification processes, biopharmaceuticals, or biotechLaboratories performing chemical analysis, quality control, or research
Employer & IndustryPharmaceutical, biotech, or chemical manufacturing companiesPharmaceutical, environmental, or food testing labs
Common Search & ComparisonPurification Scientist vs Analytical Chemist

While both roles require a background in chemistry and laboratory skills, a Purification Scientist primarily focuses on isolating and purifying compounds, often in biopharmaceuticals, whereas an Analytical Chemist specializes in analyzing and testing chemical substances for quality and composition. Both roles are essential in the drug development and manufacturing process, but their daily tasks and focus areas differ.

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Purification Scientist jobs near you
Purification Scientist

Purification Scientist

Managed Staffing

Boston, MA • On-site

$44 - $46/hr

Contractor

Posted 17 days ago

Job description

Biologist - Purification Scientist


Client: Eli Lilly and Company
Location: Boston, MA (Onsite)
Schedule: Monday–Friday | 8:00 AM–5:00 PM (40 hrs/week

Position Summary

Seeking an early-career Biologist / Purification Scientist to join the Downstream Process Development team in Boston, MA. This role will support purification and characterization of viral vectors, biologics, or recombinant proteins for process development and manufacturing activities. The ideal candidate has hands-on laboratory experience with chromatography-based purification techniques and strong documentation and collaboration skills.

Key Responsibilities

  • Execute purification processes including affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and polishing steps

  • Operate AKTA systems (Avant, Pure, Pilot) for small- to large-scale purification runs

  • Perform tangential flow filtration (TFF) for buffer exchange and product concentration

  • Prepare buffers and manage chromatography columns and consumables

  • Support experimental design, data collection, and detailed documentation in accordance with GMP/GLP practices

  • Assist with troubleshooting and optimization of purification processes

  • Analyze samples using standard analytical techniques (e.g., UV, SDS-PAGE, ELISA, ddPCR, HPLC)

  • Collaborate with upstream process, analytical, and manufacturing teams

  • Maintain laboratory equipment and ensure compliance with safety and quality standards

Required Qualifications

  • Master’s degree in Biochemistry, Biotechnology, Chemical Engineering, or a related scientific discipline

  • Minimum 2 years of hands-on purification experience in an academic or industry laboratory

  • Practical experience with ion-exchange and affinity chromatography

  • Experience with buffer preparation and basic analytical characterization methods

  • Strong attention to detail with excellent documentation practices

  • Ability to manage multiple tasks and meet project timelines

  • Effective written and verbal communication skills

Preferred Qualifications

  • Experience with AAV or other viral vector purification

  • Hands-on experience with AKTA systems and Unicorn software

  • Exposure to downstream process development or biomanufacturing environments