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Scientist Protein Chemistry Jobs (NOW HIRING)

Novartis

Senior Scientist, Protein Production

San Diego, CA · On-site

$93K - $174K/yr

We are seeking a passionate, curious, and collaborative protein scientist to join our Protein Sciences group, an interdisciplinary team that has expertise in protein chemistry, enzymology, biophysics ...

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Scientist Protein Chemistry information

What does a scientist in protein chemistry do?

A Scientist in Protein Chemistry specializes in studying the structure, function, and interactions of proteins. Their work often involves designing and conducting experiments to isolate, characterize, and modify proteins for research or therapeutic purposes. They use techniques such as chromatography, electrophoresis, and mass spectrometry, and may also be involved in protein engineering or drug discovery. These scientists typically work in academic, pharmaceutical, or biotechnology settings, contributing to advancements in medicine and biology.

How much do protein scientists make?

Protein scientists, often working as biochemists or molecular biologists, typically earn a median annual salary of around $70,000 to $100,000, depending on experience, education, and location. Salaries can increase with advanced skills, certifications, and working in industry or research institutions. Entry-level positions may start lower, while senior roles or those in biotech companies tend to pay more.

What is the difference between Scientist Protein Chemistry vs Biochemist?

AspectScientist Protein ChemistryBiochemist
Required CredentialsTypically a PhD in biochemistry, chemistry, or related fieldUsually a PhD or Master's in biochemistry, molecular biology, or related discipline
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsResearch institutions, healthcare, biotech companies
Industry UsageFocuses on protein structure, function, and interactionsBroader focus on biological molecules, including proteins, nucleic acids, and metabolites

Scientist Protein Chemistry and Biochemist roles share similar educational backgrounds and work environments, often overlapping in research settings. However, Scientist Protein Chemistry specializes specifically in protein-related research, while Biochemists have a broader focus on various biological molecules.

What are some common challenges faced by a scientist in protein chemistry, and how can they be addressed?

Scientists in Protein Chemistry often encounter challenges such as optimizing protein expression and purification, maintaining protein stability, and troubleshooting experimental protocols. Addressing these challenges typically involves staying updated on the latest methodologies, collaborating closely with team members in molecular biology and analytical chemistry, and systematically documenting experimental results to identify patterns and solutions. Open communication within multidisciplinary teams and continuous skill development are key to overcoming technical hurdles and ensuring project success.

What are the key skills and qualifications needed to thrive as a scientist in protein chemistry, and why are they important?

To thrive as a Scientist in Protein Chemistry, you need a strong background in biochemistry or molecular biology, with expertise in protein expression, purification, and characterization, typically supported by an advanced degree (Ph.D. or M.S.). Familiarity with tools such as chromatography systems (e.g., FPLC, HPLC), mass spectrometry, and relevant data analysis software is essential. Strong problem-solving abilities, attention to detail, and effective communication are valuable soft skills for this role. These skills are crucial for designing experiments, producing high-quality protein samples, and collaborating efficiently within research teams.
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Infographic showing various Scientist Protein Chemistry job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 72% Full Time, 22% Part Time, 1% Temporary, and 3% Contract. Highlights an 86% Physical, 1% Hybrid, and 13% Remote job distribution.

Associate Scientist, Protein Sciences

CytomX Therapeutics, Inc.

South San Francisco, CA

$115K - $135K/yr

Full-time

Re-posted 8 days ago

Job description

Associate Scientist, Protein Sciences
Headquarters Location: South San Francisco, CA, Company relocating to Emeryville, CA Fall of 2026
Candidate Location: Onsite for lab work
Travel Required: 5-10%
Reports To: Senior Scientist II
Department: Protein Sciences & Early CMC
Position Type: Full-time, Exempt
About CytomX Therapeutics:
CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel PROBODY therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX's robust and differentiated pipeline comprises therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engagers, and immune modulators such as cytokines. CytomX's clinical-stage pipeline includes CX-2051 and CX-801. Learn more atwww.cytomX.com.
Who You Are and What You'll Do:
You are passionate about the life sciences and making a difference for cancer patients, their families, and healthcare providers. You will be responsible for developing protein production and purification strategies to support all discovery PROBODY programs at CytomX, as well as developing analytical methods-including LC-MS-to characterize these novel molecules. Additionally, you will work closely with the Protein Engineering and Research teams to transition therapeutic programs from discovery to clinical development.
Job Responsibilities:
Develop parallel purification processes for antibodies, bispecifics and cytokines
Collaborate with discovery, protein engineering and pharmacology to provide therapeutic and reagent proteins of appropriate quality for use in in vitro and in vivo studies.
Develop production and purification strategies for various PROBODY bispecific formats
Solving protein purification problems based on scientific principles, current technologies, and personal experience
Support the lead selection process by developing various analytical, LC-MS and biophysical methods to characterize novel PROBODY molecules.
Participating in cross-functional discovery supports and effectively communicates information to appropriate groups and protein sciences staff.
Minimum Qualifications:
PhD in Biochemistry or Protein Chemistry or related discipline OR MS in Biochemistry with 5+ years of experience in the biotechnology or biopharma industry with increasing responsibility
Expertise in problem solving the protein purification issues is required.
Expertise in large and small-scale protein purification using AKTA systems, Tecan or Janus liquid handler system is required.
Expertise in protein characterization assays such as concentration, endotoxin measurement, SDS-PAGE, CE-SDS, SEC-HPLC, RP-HPLC, HIC and IEF are required.
Hands-on experience in operating HPLC or UPLC instruments is required.
Experience in developing analytical methods to characterize antibodies, bispecifics and cytokines is required.
Experience in managing the protein purification workflow is required
Please note that a presentation of a scientific seminar is required during the interview process
Preferred Qualifications:
Experience in antibody therapeutics is preferred.
Expertise in molecular biology techniques such as cloning, sequencing, etc. is desired.
Hands-on experience in operating various mass spec instruments and associated software for data analysis preferred.
Expertise in developability assessment of therapeutic biologics molecules is required
How You Will Work:
Demonstrates collaboration and teamwork. Works well with others and understands that collaboration leads to better results.
Possesses strong communication skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.
Exhibits strong interpersonal skills and self-awareness. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.
Shows continuous improvement and a commitment to self-management and development. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.
Demonstrates a patient focus. Puts the patient first in actions and decisions taken.
Compensation, Benefits, and So Much More
The expected salary range for this role based on the primary location for this position in California is $115,000 - $135,000 per year. Offer amounts are determined by factors such as experience, qualifications, geographic location, and other job-related factors permitted by law.
A great environment where we work collaboratively, leverage each other's strengths, and work toward a shared vision with our common goals of doing the best thing for patients.
A robust and enduring approach to your development and career growth fueled by a strong learning curriculum and career guidance that helps you understand how you can grow your career at CytomX.
A robust and highly competitive total rewards program that helps you achieve your compensation goals while supporting a great work / life balance.
Conditions of Employment
Background investigations are required for all positions at CytomX, consistent with applicable law.
This role is not eligible for visa sponsorship.
CytomX's Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)
CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.
Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at hr@cytomx.com
Notice to Recruiters/Staffing AgenciesRecruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at hr@cytomx.com
Please review our Applicant Personal Information Processing Notice to understand what types of personal information we collect from job applicants and why we process such information.
Employment Type: Full-Time

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