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Purification Scientist Jobs (NOW HIRING)

TechData Service Company LLC

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Formulation Scientist

Alameda, CA · On-site

$40 - $60/hr

W2 Position Summary The Lead Discovery and Structural Biology Department within client is seeking a highly qualified Protein Expression & Purification Scientist (Contractor) with demonstrated ...

LabPersonnel

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Protein Production Scientist

Lemont, IL · On-site

$27/hr

The team is searching for a contract scientist to support recombinant protein purification, sample preparation, and materials characterization in collaboration with internal teams, contract research ...

Adecco

Scientist III

Swiftwater, PA

$80/hr

Design and execute purification experiments independently while applying scientific judgment and technical expertise. * Support implementation of manufacturing process improvements and process ...

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Purification Scientist information

What are Purification Scientists?

Purification Scientists are professionals who specialize in isolating and purifying biological or chemical substances, such as proteins, antibodies, or pharmaceuticals, from complex mixtures. They develop, optimize, and scale up purification processes using techniques like chromatography, filtration, and centrifugation. These scientists often work in biotechnology, pharmaceutical, and research laboratories to ensure products are pure, safe, and effective for further research or commercial use.

How much do protein scientists make?

Protein scientists, often working as biochemists or molecular biologists, typically earn a median salary ranging from $60,000 to $100,000 annually, depending on experience, education, and location. Those with advanced degrees and specialized skills in protein purification and analysis tend to earn higher salaries, especially in research or industry settings.

What does a purification scientist do?

A purification scientist is responsible for developing and optimizing methods to isolate and purify chemical compounds, proteins, or other biological materials. They use techniques such as chromatography, filtration, and centrifugation, often working in laboratory or manufacturing settings to ensure product quality and purity. Strong analytical skills and knowledge of laboratory equipment are essential for this role.

Do you need a PhD to be a staff scientist?

A PhD is often preferred for a staff scientist position, especially in research-intensive fields like purification science, but some roles may accept a master's degree with relevant experience. Advanced degrees can enhance qualifications, but industry experience and technical skills are also important for senior scientific roles.

What are some common challenges faced by Purification Scientists, and how can they be addressed on the job?

Purification Scientists often encounter challenges such as optimizing purification protocols for novel proteins, troubleshooting unexpected impurities, and maintaining consistency across large-scale runs. These issues can be addressed by staying up-to-date with the latest chromatography techniques, collaborating closely with upstream and analytical teams, and employing robust troubleshooting and documentation practices. Being proactive in adjusting parameters and communicating effectively with colleagues helps ensure high-quality results and smooth workflow within the team.

What are the key skills and qualifications needed to thrive as a Purification Scientist, and why are they important?

To thrive as a Purification Scientist, you need a solid understanding of protein chemistry, chromatography techniques, and laboratory best practices, typically supported by a degree in biochemistry, chemistry, or a related field. Familiarity with technical tools such as HPLC, FPLC systems, and analytical software, as well as experience with relevant safety standards, is often required. Strong problem-solving skills, attention to detail, and the ability to work collaboratively are essential soft skills in this role. These qualifications ensure the efficient and accurate purification of biomolecules, which is critical for research, development, and manufacturing in pharmaceutical and biotech industries.

What is the difference between Purification Scientist vs Analytical Chemist?

AspectPurification ScientistAnalytical Chemist
Required CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fieldBachelor's or Master's in Chemistry, Analytical Chemistry, or related field
Work EnvironmentLaboratories focused on purification processes, biopharmaceuticals, or biotechLaboratories performing chemical analysis, quality control, or research
Employer & IndustryPharmaceutical, biotech, or chemical manufacturing companiesPharmaceutical, environmental, or food testing labs
Common Search & ComparisonPurification Scientist vs Analytical Chemist

While both roles require a background in chemistry and laboratory skills, a Purification Scientist primarily focuses on isolating and purifying compounds, often in biopharmaceuticals, whereas an Analytical Chemist specializes in analyzing and testing chemical substances for quality and composition. Both roles are essential in the drug development and manufacturing process, but their daily tasks and focus areas differ.

What is the highest paid type of scientist?

Among scientists, petroleum engineers and data scientists tend to have the highest salaries, often exceeding $100,000 annually. Purification scientists and other specialized roles in pharmaceuticals or biotech typically earn less but can reach higher levels with experience and advanced certifications.
More about Purification Scientist jobs
What are the most commonly searched types of Purification Scientist jobs? The most popular types of Purification Scientist jobs are:
What states have the most Purification Scientist jobs? States with the most job openings for Purification Scientist jobs include:
What job categories do people searching Purification Scientist jobs look for? The top searched job categories for Purification Scientist jobs are:
Purification Scientist jobs near you
Infographic showing various Purification Scientist job openings in the United States as of June 2026, with employment types broken down into 1% Internship, 4% As Needed, 65% Full Time, 26% Part Time, 2% Temporary, and 2% Contract. Highlights an 92% Physical, and 8% Remote job distribution.
Protein Expression Scientist - Temp

Protein Expression Scientist - Temp

System One

Alameda, CA • On-site

$50 - $55/hr

Contractor

Medical, Dental, Vision, Life, Retirement

Posted 9 days ago

Job description

Job Title: Protein Expression & Purification Scientist Location: Alameda, CA Type: 12 month contract Compensation: $50-55/hour depending on qualifications Contractor Work Model: Onsite Hours: 40 hours/week

Overview

We are seeking a Protein Expression & Purification Scientist to support drug discovery programs through the design, expression, purification, and characterization of recombinant proteins. This hands-on laboratory role requires expertise in molecular biology, protein expression systems, and chromatographic purification methods, with opportunities to contribute across multiple research initiatives in a fast-paced discovery environment.

Responsibilities

  • Design, clone, and optimize expression constructs using molecular biology techniques, including PCR, primer design, sequence verification, and recombinant cloning strategies.
  • Execute recombinant protein expression workflows using baculovirus expression vector systems (BEVS) in insect cells and E. coli expression platforms.
  • Generate, amplify, and optimize baculovirus stocks to support protein production objectives.
  • Perform high-throughput small-scale expression screening to evaluate constructs, expression conditions, and protein yield.
  • Purify recombinant proteins using affinity, ion exchange, and size-exclusion chromatography techniques.
  • Optimize expression, culture, and purification parameters to improve protein yield, purity, and overall quality.
  • Conduct analytical characterization using SDS-PAGE, Western blotting, SEC, and related protein analysis methods.
  • Document experimental procedures, results, and observations in accordance with laboratory documentation standards.
  • Analyze data, troubleshoot technical challenges, and recommend improvements to workflows and experimental strategies.
  • Communicate scientific findings and project updates effectively with cross-functional team members.

Requirements

Required Qualifications

  • Bachelor's degree in Biochemistry, Molecular Biology, Structural Biology, or a related scientific discipline with 3+ years of relevant industry experience; or Master's degree with 1+ year of relevant industry experience.
  • Strong expertise in molecular biology techniques, including cloning, vector design, construct optimization, and sequence verification.
  • Experience with PCR, primer design, restriction enzyme-based cloning, and recombination-based cloning methods.
  • Demonstrated experience expressing recombinant proteins in BEVS/insect cell systems and E. coli expression systems.
  • Experience with high-throughput small-scale protein expression screening.
  • Proficiency in protein purification using chromatographic techniques, including affinity, ion exchange, and size-exclusion chromatography.
  • Experience performing protein analytical characterization using SDS-PAGE, Western blotting, SEC, and related techniques.
  • Strong analytical, troubleshooting, and problem-solving skills.
  • Ability to independently manage experiments while collaborating effectively within multidisciplinary teams.
  • Strong organizational, documentation, and scientific communication skills.

Preferred Qualifications

  • Experience with biophysical characterization techniques such as LC-MS, SPR, MST, SEC-MALS, nanoDSF, or mass photometry.
  • Experience with protein purification method development and process optimization.
  • Familiarity with electronic laboratory notebooks, including Benchling.
  • Experience supporting protein production activities within a drug discovery or biopharmaceutical research environment.

Benefits

System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

Ref: #568-Clinical

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