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How much do protein purification jobs pay per hour?

As of Jul 22, 2026, the average hourly pay for protein purification in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What does a typical day look like for someone working in Protein Purification?

A typical day in Protein Purification involves preparing and setting up purification systems, monitoring processes such as chromatography runs, analyzing sample purity, and maintaining detailed records of results. You’ll often collaborate with research scientists, quality control teams, and other lab staff to meet project deadlines and troubleshoot purification challenges. The work environment is usually a laboratory setting, where safety protocols and attention to detail are paramount. Successful professionals in this field balance hands-on technical tasks with regular communication to ensure the smooth progression of research or manufacturing projects.

What are the key skills and qualifications needed to thrive in the Protein Purification position, and why are they important?

Excelling in Protein Purification requires a solid background in biochemistry or a related life science, with hands-on experience in laboratory techniques such as chromatography, electrophoresis, and buffer preparation. Familiarity with tools like FPLC/HPLC systems, automated fraction collectors, and relevant quality control software is crucial. Attention to detail, problem-solving skills, and strong teamwork abilities distinguish top performers in this role. These skills are essential for ensuring the accuracy, purity, and reproducibility of protein samples in research or industrial environments.

What is a Protein Purification job?

A Protein Purification job involves isolating and refining proteins from biological samples for research, pharmaceutical, or industrial applications. This process includes techniques such as chromatography, centrifugation, and filtration to achieve high purity and functionality. Professionals in this role work in laboratories, biotech firms, or pharmaceutical companies, ensuring quality control and optimizing purification protocols. Strong analytical skills and knowledge of biochemistry are essential for success in this field.

More about Protein Purification jobs
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Protein Purification jobs near you
Infographic showing various Protein Purification job openings in the United States as of July 2026, with employment types broken down into 81% Full Time, 17% Part Time, 1% Contract, and 1% Nights. Highlights an 89% Physical, 1% Hybrid, and 10% Remote job distribution, with an average salary of $68,765 per year, or $33.1 per hour.
Scientist / Membrane Protein Purification

Scientist / Membrane Protein Purification

Pioneer Data Systems Inc

Spring House, PA • On-site

Contractor

Re-posted 13 days ago

Job description

Position Details: 
Our client, a world-leading Pharmaceutical Company in Spring House, PA is currently looking for a Scientist to join their expanding team.
 
Job Title: Scientist / Membrane Protein Purification
Duration: 12 months contract, extendable up to 24 months 
Location: Spring House, PA
 
Note: 
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Notes:
Role is 100% onsite in Spring House, PA
Bachelor's degree is required
#1 Required skill: Must have processing protein production, purification experience
#2 Required skill: Must have analytical characterization experience
Membrane protein experience, a huge plus
Must have 2-4 years of experience
Will attend group meetings
60%-70% of the role will be lab based work
Will do data capturing
Must have Protein Purification and Production experience
 
Job Description:
Key Responsibilities:
Support membrane protein expression and purification.
Conduct protein production, purification and characterization.
Characterization and quality check of membrane proteins to support biotherapeutics development.
Collaborate effectively in a multi-team environment.
Contribute to both internal and external efforts in membrane protein production.
Qualifications
Education:
Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required.
Experience and Skills:
Required:
Experience with membrane protein expression and optimization, purification, and characterization of proteins
Well-versed with analytical characterization to determine quality, conformation, purity and stability
Knowledge of protein expression construct design and optimization, and expression platforms
Excellent communication skills to collaborate with internal and external partners
Preferred:
Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs
Experience in independently operating AKTA FPLC and analytical HPLC instruments
Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery
Knowledge and experience with CROs for protein production
It’s 40 hour/week full on-site job.