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Protein Purification Jobs (NOW HIRING)

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Protein Purification information

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$33

$51

How much do protein purification jobs pay per hour?

As of Sep 1, 2026, the average hourly pay for protein purification in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What is protein purification?

A Protein Purification job involves isolating and refining proteins from biological samples for research, pharmaceutical, or industrial applications. This process includes techniques such as chromatography, centrifugation, and filtration to achieve high purity and functionality. Professionals in this role work in laboratories, biotech firms, or pharmaceutical companies, ensuring quality control and optimizing purification protocols. Strong analytical skills and knowledge of biochemistry are essential for success in this field.

What does a typical day look like for someone working in protein purification?

A typical day in Protein Purification involves preparing and setting up purification systems, monitoring processes such as chromatography runs, analyzing sample purity, and maintaining detailed records of results. You’ll often collaborate with research scientists, quality control teams, and other lab staff to meet project deadlines and troubleshoot purification challenges. The work environment is usually a laboratory setting, where safety protocols and attention to detail are paramount. Successful professionals in this field balance hands-on technical tasks with regular communication to ensure the smooth progression of research or manufacturing projects.

What are the key skills and qualifications needed to thrive in protein purification, and why are they important?

Excelling in Protein Purification requires a solid background in biochemistry or a related life science, with hands-on experience in laboratory techniques such as chromatography, electrophoresis, and buffer preparation. Familiarity with tools like FPLC/HPLC systems, automated fraction collectors, and relevant quality control software is crucial. Attention to detail, problem-solving skills, and strong teamwork abilities distinguish top performers in this role. These skills are essential for ensuring the accuracy, purity, and reproducibility of protein samples in research or industrial environments.

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What cities are hiring for Protein Purification jobs?

Cities with the most Protein Purification job openings:

What states have the most Protein Purification jobs?

States with the most job openings for Protein Purification jobs include:

Infographic showing various Protein Purification job openings in the United States as of August 2026, with employment types broken down into 81% Full Time, 15% Part Time, 3% Contract, and 1% Nights. Highlights an 88% Physical, 1% Hybrid, and 11% Remote job distribution, with an average salary of $68,765 per year, or $33.1 per hour.

Scientist / Protein Purification

Cambridge, MA • On-site

Contractor

Posted 18 days ago


Job description

Position Details:
Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for an Scientist to join their expanding team.
 
Job Title: Scientist / Protein Purification
Duration: 24 months contract, extendable up to 48 months
Location: Cambridge, MA
 
Note:
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Job Description:
We are seeking a motivated Bench Scientist to join a biotherapeutics research team in Cambridge, MA.
This is a hands-on laboratory position focused primarily on recombinant protein expression, purification, and characterization to support downstream biotherapeutic research.

Key Responsibilities
Perform routine recombinant protein purification using FPLC/AKTA and related chromatography techniques.
Support the production of recombinant proteins and antigens for downstream biotherapeutic research.
Participate in protein expression workflows and, as needed, molecular biology/DNA-related activities.
Perform protein characterization and assess protein quality, purity, concentration, and suitability for downstream applications.
Work with antigens, antibodies, mAbs, Fabs, and other recombinant proteins.
Perform routine protein labeling and conjugation, including fluorescent and biotin labeling.
Assist with analytical techniques such as SDS-PAGE, Western blotting, and HPLC.
Maintain accurate laboratory records, sample tracking, and experimental documentation.
Manage multiple protein-production and purification requests while meeting project timelines.
Work collaboratively with scientists across the research organization and provide purified proteins for downstream studies.
Maintain a clean, organized, and compliant laboratory environment and follow all required laboratory safety and PPE procedures.

Required Qualifications
Bachelor's degree in Biochemistry, Biology, Chemistry, Molecular Biology, or a related scientific discipline.
At least 1 year of hands-on experience with recombinant protein purification or a closely related protein-science discipline.
Hands-on experience with AKTA/FPLC or comparable chromatography systems.
Understanding of protein purification and characterization principles.
Strong laboratory organization and time-management skills.
Ability to work effectively in a collaborative, fast-paced research environment.

Preferred Qualifications
Master's degree in Biochemistry, Biology, Biophysics, Molecular Biology, or a related field.
Experience with recombinant protein expression.
Experience with protein biophysics and protein characterization.
Experience working with antibodies, mAbs, Fabs, or recombinant antigens.
Background in immunology or biotherapeutic research.