ZipRecruiter

Log In

1

Protein Purification Jobs (NOW HIRING)

Amgen

Scientist - Protein Biochemist

Thousand Oaks, CA · On-site

Develop and optimize purification protocols and reagents, ensuring high protein purity, homogeneity, and stability for structural studies. * Characterization and Quality Control: Use biochemical and ...

Zealand Pharma

$75 - $125/hr

JR360Does it excite you to build a strong foundation in modern protein purification and analytical technologies, and are you eager to grow your scientific career from the ground up? If this sounds ...

previous pagenext page

Showing results 21-40

All JobsProtein Purification Jobs

Protein Purification information

See salary details

$17

$33

$51

How much do protein purification jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for protein purification in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What is protein purification?

A Protein Purification job involves isolating and refining proteins from biological samples for research, pharmaceutical, or industrial applications. This process includes techniques such as chromatography, centrifugation, and filtration to achieve high purity and functionality. Professionals in this role work in laboratories, biotech firms, or pharmaceutical companies, ensuring quality control and optimizing purification protocols. Strong analytical skills and knowledge of biochemistry are essential for success in this field.

What does a typical day look like for someone working in protein purification?

A typical day in Protein Purification involves preparing and setting up purification systems, monitoring processes such as chromatography runs, analyzing sample purity, and maintaining detailed records of results. You’ll often collaborate with research scientists, quality control teams, and other lab staff to meet project deadlines and troubleshoot purification challenges. The work environment is usually a laboratory setting, where safety protocols and attention to detail are paramount. Successful professionals in this field balance hands-on technical tasks with regular communication to ensure the smooth progression of research or manufacturing projects.

What are the key skills and qualifications needed to thrive in protein purification, and why are they important?

Excelling in Protein Purification requires a solid background in biochemistry or a related life science, with hands-on experience in laboratory techniques such as chromatography, electrophoresis, and buffer preparation. Familiarity with tools like FPLC/HPLC systems, automated fraction collectors, and relevant quality control software is crucial. Attention to detail, problem-solving skills, and strong teamwork abilities distinguish top performers in this role. These skills are essential for ensuring the accuracy, purity, and reproducibility of protein samples in research or industrial environments.

More about Protein Purification jobs

What cities are hiring for Protein Purification jobs?

Cities with the most Protein Purification job openings:

What states have the most Protein Purification jobs?

States with the most job openings for Protein Purification jobs include:

What job categories do people searching Protein Purification jobs look for?

The top searched job categories for Protein Purification jobs are:

Protein Purification jobs near you
Infographic showing various Protein Purification job openings in the United States as of August 2026, with employment types broken down into 81% Full Time, 15% Part Time, 3% Contract, and 1% Nights. Highlights an 88% Physical, 1% Hybrid, and 11% Remote job distribution, with an average salary of $68,765 per year, or $33.1 per hour.

Scientist - Protein Production

Helix Biostructures

Indianapolis, IN • On-site

Full-time

Medical, Dental, Vision, Retirement

Re-posted 27 days ago

Job description

Scientist - Protein Production
Helix BioStructures, LLC (HBS) is a contract research organization (CRO) based in Indianapolis, Indiana, providing early drug discovery services to the biopharmaceutical industry. HBS maintains a full suite of services that encompass chemical & structural analysis, protein production, computational modeling, and design. HBS's core and most popular services are structural biology imaging techniques: X-ray Crystallography and Cryo-EM. HBS was founded in 2018 and has grown considerably. We are looking to add a Scientist focused on protein production to join our Indianapolis-based team.
Main Responsibilities
This scientist will support our protein production pipeline by expressing and purifying recombinant proteins in bacterial, insect, and mammalian systems; performing biophysical characterization to assess sample quality and stability; developing and optimizing expression and purification protocols; interfacing with our clients; and writing technical project reports. The scientist will also contribute to improving expression and purification methods to accelerate research processes.
Highly desirable hands-on experiences include:
(a) Experience in recombinant protein expression and purification across bacterial, insect, and mammalian cell lines.
(b) Use of biophysical and analytical techniques (e.g., SDS-PAGE, SEC, Western Blot, TSA, DLS, Mass Spectrometry, and others) to assess protein quality, purity, and stability.
This scientist will employ a range of experimental methods (biochemical, biophysical, and/or computational) to support our clients' structure-based drug discovery, antibody discovery, and/or protein engineering. Accordingly, proficiency in recombinant protein expression and purification and a passion for generating high-quality, well-characterized protein reagents are essential. Any structural biology experience (X-ray crystallography or Cryo-EM) is a plus, but is not required for this role. The successful candidate will be a strong technical contributor who can execute reliably at the bench and collaborate with colleagues on multiple projects in parallel. This role is open to candidates ranging from entry-level to experienced scientists; the level of hire, scope, and degree of independence will be determined by the candidate's experience and qualifications, with the opportunity to help drive discovery projects from inception through early development.
Additional Responsibilities
  • Express and purify proteins to target quality and yield within industrial timeframes.
  • Document experimental data and communicate research priorities, progress, and results with clients/project teams.
  • Provide technical and scientific input to project teams, with the scope of guidance to other members of the Protein Sciences group, scaling with seniority and experience.
  • The candidate will be responsible for timely updates on project statuses, reporting to their supervisor informally and to Helix's customers by formal report writing and oral presentations.

Required Qualifications
This position is open to candidates ranging from entry-level to experienced scientists. The qualifications below represent the minimum requirements for the role; the final level of hire will be determined based on the candidate's experience and qualifications.
  • D. in biochemistry, biophysics, molecular biology, protein engineering, or a related field; OR a Master's degree with 2-5 years of relevant industrial experience; OR a Bachelor's degree with 5-10 years of relevant industrial experience.
  • Demonstrated competency in recombinant protein expression and purification using bacterial, insect, and mammalian cell lines; hands-on experience across all three systems is strongly preferred.
  • Ability to generate and characterize milligram to gram quantities of high-quality protein reagents for downstream studies.
  • Experience with standard analytical and biophysical techniques (e.g., SDS-PAGE, SEC, Western Blot, TSA, DLS, Mass Spectrometry, and others) for assessing protein quality, purity, and stability during purification.
  • Strong written and oral communication skills.

Additional qualifications
  • Hands-on experience in engineering protein constructs and optimizing the production of protein targets for structural and functional studies.
  • Experience in structural biology is a plus but not required, including protein X-ray crystallography (sample assessment, crystallization, optimization, data collection, and structure determination/refinement) and familiarity with software such as Phenix, CCP4, Coot, and PyMOL.
  • Experience with protein engineering and/or design approaches.
  • Analysis, design, and/or computational approaches to investigate ligand-protein complexes.
  • Experience with Cryo-EM is a plus, especially grid vitrification and screening.
  • Excellent communication, interpersonal, and organizational skills.
  • Willingness to tackle challenging technical problems.

Location
This position is based in Indianapolis, Indiana, and does NOT offer a hybrid option. Interaction with external service vendors is also expected. Candidates must be authorized to work in the United States; Helix BioStructures does NOT provide visa sponsorship for this position.
Physical Requirements
Able to lift 30 lb objects with dimensions 30 inches in height and 18 inches in width.
Able to visualize microscopic objects under microscopes.
Non-standard work schedule, travel, and lab safety
Able to adhere to safe work practices and perform lab work with appropriate personal protective equipment, such as but not limited to safety goggles, facial mask, gloves, lab coat/ protective gowning, and closed-toe shoes. Able to work at flexible hours occasionally when performing time-sensitive experiments.
Other job details
  • Eligible for Relocation Package
  • Competitive Salary + annual bonus
  • Retirement (matching 401K)
  • Health/Dental/Vision Insurance
  • Company Apple Computer

Helix BioStructures, LLC is an equal opportunity employer, and we embrace the increasingly diverse world around us. Helix BioStructures, LLC prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status.

Apply