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Purification Scientist Jobs (NOW HIRING)

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Scientist

Watertown, MA · On-site

Associate Scientist / Scientist - xRNA Process Sciences Overview We are seeking an Associate ... Perform RNA purification using chromatography systems, including AKTA-based purification workflows.

3 Key Consulting

$36 - $41/hr

Will partner with manufacturing, quality, analytical, and bench scientists to support a highly ... Purification of monoclonal antibodies * Experience in GMP environment (preferably in drug substance ...

Actalent

Production Scientist

Cary, NC

$30/hr

Job Title: Production Scientist The Production Scientist supports early-phase development of Active Pharmaceutical Ingredients (APIs) by synthesizing small organic molecules and API-related ...

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Purification Scientist information

What are Purification Scientists?

Purification Scientists are professionals who specialize in isolating and purifying biological or chemical substances, such as proteins, antibodies, or pharmaceuticals, from complex mixtures. They develop, optimize, and scale up purification processes using techniques like chromatography, filtration, and centrifugation. These scientists often work in biotechnology, pharmaceutical, and research laboratories to ensure products are pure, safe, and effective for further research or commercial use.

How much do protein scientists make?

Protein scientists, often working as biochemists or molecular biologists, typically earn a median salary ranging from $60,000 to $100,000 annually, depending on experience, education, and location. Those with advanced degrees and specialized skills in protein purification and analysis tend to earn higher salaries, especially in research or industry settings.

What does a purification scientist do?

A purification scientist is responsible for developing and optimizing methods to isolate and purify chemical compounds, proteins, or other biological materials. They use techniques such as chromatography, filtration, and centrifugation, often working in laboratory or manufacturing settings to ensure product quality and purity. Strong analytical skills and knowledge of laboratory equipment are essential for this role.

Do you need a PhD to be a staff scientist?

A PhD is often preferred for a staff scientist position, especially in research-intensive fields like purification science, but some roles may accept a master's degree with relevant experience. Advanced degrees can enhance qualifications, but industry experience and technical skills are also important for senior scientific roles.

What are some common challenges faced by Purification Scientists, and how can they be addressed on the job?

Purification Scientists often encounter challenges such as optimizing purification protocols for novel proteins, troubleshooting unexpected impurities, and maintaining consistency across large-scale runs. These issues can be addressed by staying up-to-date with the latest chromatography techniques, collaborating closely with upstream and analytical teams, and employing robust troubleshooting and documentation practices. Being proactive in adjusting parameters and communicating effectively with colleagues helps ensure high-quality results and smooth workflow within the team.

What are the key skills and qualifications needed to thrive as a Purification Scientist, and why are they important?

To thrive as a Purification Scientist, you need a solid understanding of protein chemistry, chromatography techniques, and laboratory best practices, typically supported by a degree in biochemistry, chemistry, or a related field. Familiarity with technical tools such as HPLC, FPLC systems, and analytical software, as well as experience with relevant safety standards, is often required. Strong problem-solving skills, attention to detail, and the ability to work collaboratively are essential soft skills in this role. These qualifications ensure the efficient and accurate purification of biomolecules, which is critical for research, development, and manufacturing in pharmaceutical and biotech industries.

What is the difference between Purification Scientist vs Analytical Chemist?

AspectPurification ScientistAnalytical Chemist
Required CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fieldBachelor's or Master's in Chemistry, Analytical Chemistry, or related field
Work EnvironmentLaboratories focused on purification processes, biopharmaceuticals, or biotechLaboratories performing chemical analysis, quality control, or research
Employer & IndustryPharmaceutical, biotech, or chemical manufacturing companiesPharmaceutical, environmental, or food testing labs
Common Search & ComparisonPurification Scientist vs Analytical Chemist

While both roles require a background in chemistry and laboratory skills, a Purification Scientist primarily focuses on isolating and purifying compounds, often in biopharmaceuticals, whereas an Analytical Chemist specializes in analyzing and testing chemical substances for quality and composition. Both roles are essential in the drug development and manufacturing process, but their daily tasks and focus areas differ.

What is the highest paid type of scientist?

Among scientists, petroleum engineers and data scientists tend to have the highest salaries, often exceeding $100,000 annually. Purification scientists and other specialized roles in pharmaceuticals or biotech typically earn less but can reach higher levels with experience and advanced certifications.
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Purification Scientist jobs near you
Infographic showing various Purification Scientist job openings in the United States as of June 2026, with employment types broken down into 1% Internship, 4% As Needed, 65% Full Time, 26% Part Time, 2% Temporary, and 2% Contract. Highlights an 92% Physical, and 8% Remote job distribution.

Scientist AAV Purification - Gene Therapy

KMR Search Group

San Rafael, CA • On-site

Full-time

Posted 19 hours ago

Job description


Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases.
Looking for a highly motivated team member with extensive experience in AAV downstream purification to be a key contributor in the Genetics Research and Delivery Group.Incumbent will be responsible for supporting the purification of research grade AAV vectors and downstream process development efforts within the Genetics Research and Delivery Group.
RESPONSIBILITIES
  • Support the purification of research grade AAV vectors for early stage research projects
  • Independently design and conduct purification projects and process development activities including column and membrane chromatography, filtration and membrane separations, scale-up, and technology transfer to Process Sciences.
  • Drive design of experimental studies needed to support process improvements to enhance process reliability, improve process yields and develop strategies for scale-up
  • Partner with the Upstream and Analytical leads in Research and Process Sciences to build effective CMC strategies for gene therapy candidates
  • Support the investigation and evaluation of novel and innovative technologies for AAV downstream processes

EXPERIENCE
  • Ph.D. in chemical engineering, biochemical engineering, biochemistry, or a related field with 2-5 years of relevant experience, Master's degree with 6-8 years of relevant experience or a Bachelor's degree with a minimum of 8 years of relevant experience.
  • A strong understanding of AAV biology and the fundamentals of AAV purification operations including chromatography and/or membrane separations is required.
  • Demonstrated experience developing successful harvest, filtration, chromatography and other AAV unit operations
  • Hands-on experience with upstream production and AAV analytics is preferred
  • Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines

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