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Director Technical Operations Jobs in Raleigh, NC

MedPharm

Sr. Director, Technical Operations

Durham, NC · On-site

Position Summary The Sr. Director, Technical Operations is responsible for providing key leadership, direction, organization, management, monitoring, and cGMP compliance of the roles, activities, and ...

MedPharm

Sr. Director, Technical Operations

Durham, NC · On-site

Position Summary The Sr. Director, Technical Operations is responsible for providing key leadership, direction, organization, management, monitoring, and cGMP compliance of the roles, activities, and ...

Syner-G

Regional Director, Southeast

Raleigh, NC

POSITION OVERVIEW: We are seeking a dynamic and motivated Regional Director of Technical Operations, Southeast to lead our operations and growth strategy in the Raleigh-Durham area, with ...

Syner-G

Regional Director, Southeast

Raleigh, NC · On-site

We are seeking a dynamic and motivated Regional Director of Technical Operations, Southeast to lead our operations and growth strategy in the Raleigh-Durham area, with accountability for performance ...

Syner-G

Regional Director, Southeast

Raleigh, NC

We are seeking a dynamic and motivated Regional Director of Technical Operations, Southeast to lead our operations and growth strategy in the Raleigh-Durham area, with accountability for performance ...

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All JobsTechnical Operations JobsDirector Technical Operations JobsDirector Technical Operations Jobs in Raleigh, NC

Director Technical Operations information

See Raleigh, NC salary details

$58.8K

$136.4K

$189.5K

How much do director technical operations jobs pay per year?

As of Jul 30, 2026, the average yearly pay for director technical operations in Raleigh, NC is $136,387.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,200.00 and $166,200.00 per year, depending on experience, location, and employer.

What is the difference between Director Technical Operations vs Operations Manager?

AspectDirector Technical OperationsOperations Manager
Required CredentialsBachelor's or Master's in Engineering, Business, or related field; often certifications in project management or technical areasBachelor's degree in Business, Management, or related field; certifications like PMP are common
Work EnvironmentOversees multiple teams, strategic planning, high-level decision making in technical settingsManages daily operations, team supervision, process implementation at the departmental level
Employer & Industry UsageUsed in tech, manufacturing, and engineering firms for senior technical leadershipCommon across various industries for operational oversight at the team or department level

The main difference is that the Director Technical Operations focuses on strategic, high-level technical oversight and long-term planning, while the Operations Manager handles day-to-day operational management and team supervision. Both roles require technical knowledge, but the director role is more strategic and broad in scope.

What does a Director of Technical Operations do?

A Director of Technical Operations oversees the technical aspects of a company's operations, ensuring that systems, processes, and teams function efficiently and effectively. They manage technical teams, develop strategies for system improvements, and coordinate cross-department efforts to meet organizational goals. Their responsibilities often include implementing best practices, maintaining service quality, and overseeing budgets and resource allocation for technical projects. This leadership role requires strong technical knowledge, management skills, and the ability to align technology initiatives with business objectives.

How does a Director of Technical Operations typically collaborate with cross-functional teams to achieve organizational goals?

A Director of Technical Operations frequently partners with teams across engineering, product management, customer support, and IT to drive seamless technology delivery and operational efficiency. This role often involves coordinating large-scale projects, aligning technical resources with business priorities, and facilitating communication between technical and non-technical stakeholders. Effective collaboration ensures that operational strategies support overall company objectives and that projects are delivered on time and within budget. Regular meetings, status updates, and joint planning sessions are common practices to maintain alignment and foster a collaborative culture.

What are the key skills and qualifications needed to thrive as a Director of Technical Operations, and why are they important?

To excel as a Director of Technical Operations, you need extensive experience in operations management, project leadership, and a solid background in engineering or information technology, often backed by a relevant degree. Familiarity with IT service management tools, cloud platforms, and certifications like ITIL or PMP are commonly required. Exceptional communication, strategic thinking, and team leadership are critical soft skills that set high performers apart. These qualities are essential for aligning technical teams with business goals, ensuring efficient operations, and driving organizational growth.
What are the most commonly searched types of Technical Operations jobs in Raleigh, NC? The most popular types of Technical Operations jobs in Raleigh, NC are:
What are popular job titles related to Director Technical Operations jobs in Raleigh, NC? For Director Technical Operations jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Director Technical Operations jobs in Raleigh, NC look for? The top searched job categories for Director Technical Operations jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Director Technical Operations jobs? Cities near Raleigh, NC with the most Director Technical Operations job openings:
Director Technical Operations jobs near you
Infographic showing various Director Technical Operations job openings in Raleigh, NC as of July 2026, with employment types broken down into 1% As Needed, 83% Full Time, 13% Part Time, 1% Temporary, and 2% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $136,387 per year, or $65.6 per hour.

Senior Director, Technical Operations

Oxford Biomedica

Durham, NC • On-site

Full-time

Posted 15 days ago

Job description

At OXB, our people are at the heart of everything we do. We're on a mission to enable life-changing therapies to reach patients around the world-and we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.
Following the expansion of our US footprint with the acquisition of a new commercial-scale viral vector facility in Durham, North Carolina we have some new opportunities to join us.
We are recruiting a Sr Director, Technical Operations to join the Durham Leadership Team. Reporting directly into the Durham Site Head, this role will provide strategic and operational oversight for Manufacturing, MSAT, and Engineering, ensuring the reliable, compliant, and efficient delivery of clinical and commercial gene therapy programs. Partnering closely with the Bedford Process Development team, colleagues across the OXB network, and site leadership, this role will drive operational excellence, strengthen site capabilities, and enable future growth while delivering high-quality viral vector manufacturing solutions that improve patient lives.
Your responsibilities in this role would be:
  • Provide strategic leadership across Manufacturing, MSAT, and Engineering, ensuring technical operations are aligned with business objectives and optimized to support pilot, clinical, and commercial manufacturing activities.
  • Lead, develop, and empower a high-performing technical operations organisation, fostering a culture of safety, quality, accountability, collaboration, and continuous improvement.
  • Build and scale manufacturing capabilities through effective capacity planning, resource allocation, workforce development, and infrastructure investment to support current operations and future business growth.
  • Ensure reliable, compliant, and efficient GMP operations by establishing robust manufacturing and engineering systems, maintaining regulatory compliance, and driving effective technical troubleshooting and operational problem-solving.
  • Partner closely with Client Project Management, Technical Excellence, Process Development, Quality, Program Management, and Supply Chain teams to enable successful process transfers, manufacturing readiness, and delivery of client commitments.
  • Drive operational excellence and business performance through lean methodologies, performance management, budget oversight, infrastructure optimisation, and strategic initiatives that improve productivity, efficiency, and cost effectiveness.

We are looking for:
  • Bachelor's degree in Engineering, Life Sciences, Manufacturing, Business, or related field required; advanced degree preferred.
  • 15+ years progressive experience in biopharmaceutical manufacturing or technical operations leadership.
  • 5+ years leading leaders (Director-level or equivalent leadership teams).
  • Significant experience operating within clinical and commercial cGMP manufacturing environments, ideally within gene therapy, viral vectors, cell therapy, biologics, or other advanced therapy modalities.
  • Proven success leading multi-functional technical operations organisations, including manufacturing and engineering functions, within highly regulated FDA and EMA environments.
  • Deep understanding of GMP manufacturing operations, technical operations infrastructure, engineering systems, and manufacturing support functions, with experience supporting site growth, scale-up, or operational transformation.
  • Demonstrated ability to drive strategic planning, operational excellence, continuous improvement, and manufacturing performance through effective leadership, decision-making, and risk management.
  • Strong commercial and financial acumen, including budget ownership, resource planning, and cost management, combined with excellent stakeholder management and communication skills

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.
About Us:
OXB (LSE: OXB) is a global quality and innovation-led contract development and manufacturing organisation (CDMO) in cell and gene therapy with a mission to enable its clients to deliver life changing therapies to patients around the world.
One of the original pioneers in cell and gene therapy, OXB has 30 years of experience in viral vectors; the driving force behind the majority of cell and gene therapies. OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV), adenovirus and other viral vector types. OXB's world-class capabilities range from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.
OXB offers a vast number of technologies for viral vector manufacturing, including a 4th generation lentiviral vector system (the TetraVecta™ system), a dual-plasmid system for AAV production, suspension and perfusion process using process enhancers and stable producer and packaging cell lines.
OXB, a FTSE250 and FTSE4Good constituent, is headquartered in Oxford, UK. It has development and manufacturing facilities across Oxfordshire, UK, Lyon and Strasbourg, France, Bedford MA, and Durham NC, US.
Why Join Us?
  • Competitive total reward packages
  • Wellbeing programs that support your mental and physical health
  • Career development opportunities to help you grow and thrive
  • Supportive, inclusive, and collaborative culture
  • State-of-the-art labs and manufacturing facilities
  • A company that lives its values: Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, we're future-focused and growing fast. We succeed together-through passion, commitment, and teamwork.
Ready to Make a Difference?

Apply