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Director Commercial Operations Biotech Jobs (NOW HIRING)

Motional

Director, Commercial Operations

Las Vegas, NV · On-site

The Director of Commercial Operations is a critical senior management team member and is responsible for the safe and reliable operation of Motional's commercial fleet and supporting commercial ...

Motional

Director, Commercial Operations

Las Vegas, NV · On-site

The Director of Commercial Operations is a critical senior management team member and is responsible for the safe and reliable operation of Motional's commercial fleet and supporting commercial ...

GLG

Director, Commercial Operations

New York, NY

Position Overview The Director of Commercial Operations is a senior strategic role at the leadership table of GLG's Professional Services & Corporate revenue engine, reporting to the Global Head of ...

GLG

Director, Commercial Operations

New York, NY · On-site

Position Overview The Director of Commercial Operations is a senior strategic role at the leadership table of GLG's Professional Services & Corporate revenue engine, reporting to the Global Head of ...

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$34K

$107.7K

$179.5K

How much do director commercial operations biotech jobs pay per year?

As of Jun 10, 2026, the average yearly pay for director commercial operations biotech in the United States is $107,680.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,500.00 and $135,500.00 per year, depending on experience, location, and employer.

What is the difference between Director Commercial Operations Biotech vs Commercial Manager Biotech?

AspectDirector Commercial Operations BiotechCommercial Manager Biotech
ResponsibilitiesOversees overall commercial strategy, leads teams, manages budgets, and aligns sales and marketing effortsManages sales teams, executes marketing plans, and supports revenue targets within specific regions or products
Required CredentialsTypically requires advanced degrees (MBA, PhD), extensive industry experience, leadership skillsRequires bachelor's or master's degree, sales or marketing experience, industry knowledge
Work EnvironmentStrategic, leadership-focused, often in corporate offices or headquartersOperational, team management, often in regional offices or field settings

The main difference is that the Director Commercial Operations Biotech focuses on strategic leadership and overall commercial planning, while the Commercial Manager Biotech handles day-to-day sales and marketing execution. The director role involves higher-level decision-making and cross-department coordination, whereas the manager role is more tactical and region-specific.

What does a Director of Commercial Operations in Biotech do?

A Director of Commercial Operations in Biotech oversees the business functions that support the marketing, sales, and distribution of biotechnology products. They are responsible for developing and executing commercial strategies, managing cross-functional teams, and ensuring operational efficiency to maximize revenue and market share. Their role involves close collaboration with product development, regulatory, sales, and marketing teams to align business objectives with market needs. They also analyze market trends, customer needs, and competitive landscapes to guide company growth. Ultimately, they play a critical role in bringing innovative biotech products to market successfully.

How does the Director of Commercial Operations in biotech typically collaborate with cross-functional teams to drive product launch success?

As a Director of Commercial Operations in biotech, you'll work closely with sales, marketing, regulatory, supply chain, and medical affairs teams to ensure seamless product launches. This involves aligning launch strategies, coordinating timelines, overseeing commercial readiness, and ensuring compliance with industry regulations. Regular cross-functional meetings, joint planning sessions, and shared performance metrics are common practices to facilitate collaboration. Building strong relationships across departments is key to effectively responding to market dynamics and achieving launch milestones.

What are the key skills and qualifications needed to thrive as a Director of Commercial Operations in Biotech, and why are they important?

To thrive as a Director of Commercial Operations in Biotech, you need a deep understanding of the pharmaceutical or biotech industry, commercial strategy, and business development, often supported by an advanced degree in life sciences or business. Familiarity with CRM systems, data analytics platforms, and regulatory compliance tools is typically required. Strong leadership, communication, and strategic thinking skills set top performers apart in this role. These abilities ensure effective market strategy execution, compliance, and cross-functional team alignment crucial for commercial success in the biotech sector.
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Director Commercial Operations Biotech jobs near you
Infographic showing various Director Commercial Operations Biotech job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 94% Full Time, and 5% Part Time. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $107,680 per year, or $51.8 per hour.

Director, Commercial Operations

Osteal Therapeutics

Dallas, TX • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 13 days ago

Job description

Osteal Therapeutics is a Dallas-based, privately held biotechnology company redefining the standard of care for life-altering orthopedic infections.
Osteal is hiring to launch NEXCHANGE™ KIT, a first-of-its-kind FDA Breakthrough Therapy for periprosthetic joint infection (PJI), a critical condition impacting 50,000 Americans annually. PJI currently lacks FDA-approved therapies and forces patients through grueling, months-long treatments with poor outcomes. Our disruptive technology transforms this journey by safely delivering high-concentration, broad-spectrum antibiotics directly to the infection site; reducing the treatment timeline from months to just seven days.
Powered by $137M in funding to date and a distinguished investor base that includes strategic partners Johnson & Johnson and Zimmer Biomet, we are advancing toward FDA approval and building the organization that will bring this therapy to patients in dire need.
We are looking for bold, relentless professionals who thrive in a "builder" environment. If you are driven by the opportunity to do work that genuinely matters - to be part of a cohesive and capable team striving to deliver the first on-label PJI treatment that promises to transform outcomes for tens of thousands of patients.
About This Job
The Commercial Operations Director will play a central role in ensuring the effective and efficient delivery of a potentially groundbreaking targeted infection therapy for musculoskeletal infections.
This position will have responsibility for supporting the commercial organization in the design, development, and maintenance of programs, processes, tools, and practices. The role will have responsibility building out and maintaining the commercial systems required for commercialization. It will also be responsible for execution of sales planning and operations, data analytics and insights, and reporting.
The Commercial Operations Director will manage, generate, interpret, and communicate insights driven analytics across all commercial functions with responsibility for developing dashboards to track key performance indicators (KPI).
Responsibilities
Technology
  • Collaborate with Commercial stakeholders to design, deliver and maintain technology solutions that align to Commercial's business strategic direction.
  • Design, develop, implement and lead the company's customer management system (CRM) with input from Commercial, IT, Quality and Finance.
  • Support the build, implementation, and maintenance of sales tools, including CRM, data analytics, and sales dashboards.
  • Lead the development of databases and infrastructure to support analytics, insights, forecasting and budgeting.

Data Analytics & Reporting
  • Work with cross-functional team members to identify and prioritize actionable, high-impact insights across a variety of core business areas including Sales, Marketing, Finance and Market Access.
  • Oversee market insights, analytics and competitive intelligence to deliver data driven business recommendations.
  • Research, design, implement, and validate cutting-edge dashboards to analyze diverse sources of data to achieve targeted outcomes.
  • Institute processes for data and reporting governance of ad-hoc field-based inquiries from the Executive Leadership Team and other Commercial functions.
  • Lead data inquiry and data stewardship efforts in support of field-based teams.

Field Management
  • Strategic and tactical planning for field teams including management of vehicle allowance, incentive compensation design and administration, data management, reporting, and CRM management.
  • Oversee field effectiveness and operations, including territory planning, sales performance tracking and analytics, incentive programming, and the development and delivery of customer engagement and sales enablement tools.
  • Design, develop, implement and manage an integrated Case Managment utility to ensure efficient coordination of NexChange procedure.

Budget & Forecast Management
  • Develop and oversee the operational budget, ensuring efficient allocation of resources and monitoring of key performance indicators (KPIs) to drive cost reduction and service improvement
  • Work closely with Commercial and Finance to ensure accurate forecasting reporting.

Trade & Distrubution
  • Develop a deep knowledge of the channel strategy along with standard of care fluency to support case logistics in the field by ensuring drug, device and representative readiness.
  • Support the head of trade and distribution with data, reporting, and inventory management.

Launch Readiness
  • Lead cross-functional launch readiness meetings, track risks, and manage cross-functional partners
  • Closely collaborate with leadership and support strategic cross-functional initiatives
  • Drive operational alignment, enablement, execution excellence and continuous improvement of commercial operations

Requirements
  • Bachelor's degree required; advanced degree (MBA or related discipline) preferred.
  • 10+ years of progressive commercial operations experience within biotechnology, pharmaceuticals, medical devices, or combination product organizations.
  • Prior launch experience supporting specialty products, hospital-based therapies, or complex reimbursement environments.
  • Demonstrated success building commercial infrastructure and operational processes within emerging or high-growth companies.
  • Experience supporting market access, reimbursement, and contracting operations.
  • Strong analytical and strategic planning capabilities with experience leveraging commercial data to drive business decisions.
  • Experience with CRM systems, commercial analytics platforms, and sales operations tools.
  • Exceptional cross-functional leadership, communication, and organizational skills.
  • Ability to thrive in a fast-paced, hands-on start-up environment with evolving priorities.
  • Willingness to travel as needed.

Our Benefits
  • 100% of Health Insurance paid by OstealTx for Employee & Dependents
  • Dental & Vision Insurance
  • Short & Long Term Disability Insurance paid 100% by OstealTx
  • 401k (Regular & Roth)
  • Holiday Pay & PTO
  • Competitive compensation: ($220,000 -$260,000) + Bonus + Equity

Osteal Therapeutics is an Equal Opportunity Employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to protected characteristics such as race, color, religion, sex, national origin, age, disability, or veteran status.

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