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Director Commercial Operations Biotech Jobs in California

The Director, Commercial Operations defines and leads the commercial operating system for the DSO business and shares accountability for DSO growth, profitability, customer retention, and execution ...

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Director Commercial Operations Biotech information

What does a director of commercial operations in biotech do?

A Director of Commercial Operations in Biotech oversees the business functions that support the marketing, sales, and distribution of biotechnology products. They are responsible for developing and executing commercial strategies, managing cross-functional teams, and ensuring operational efficiency to maximize revenue and market share. Their role involves close collaboration with product development, regulatory, sales, and marketing teams to align business objectives with market needs. They also analyze market trends, customer needs, and competitive landscapes to guide company growth. Ultimately, they play a critical role in bringing innovative biotech products to market successfully.

What are the key skills and qualifications needed to thrive as a director of commercial operations in biotech?

To thrive as a Director of Commercial Operations in Biotech, you need a deep understanding of the pharmaceutical or biotech industry, commercial strategy, and business development, often supported by an advanced degree in life sciences or business. Familiarity with CRM systems, data analytics platforms, and regulatory compliance tools is typically required. Strong leadership, communication, and strategic thinking skills set top performers apart in this role. These abilities ensure effective market strategy execution, compliance, and cross-functional team alignment crucial for commercial success in the biotech sector.

How does the director of commercial operations in biotech typically collaborate with cross-functional teams to drive product launch success?

As a Director of Commercial Operations in biotech, you'll work closely with sales, marketing, regulatory, supply chain, and medical affairs teams to ensure seamless product launches. This involves aligning launch strategies, coordinating timelines, overseeing commercial readiness, and ensuring compliance with industry regulations. Regular cross-functional meetings, joint planning sessions, and shared performance metrics are common practices to facilitate collaboration. Building strong relationships across departments is key to effectively responding to market dynamics and achieving launch milestones.

What is the difference between Director Commercial Operations Biotech vs Commercial Manager Biotech?

AspectDirector Commercial Operations BiotechCommercial Manager Biotech
ResponsibilitiesOversees overall commercial strategy, leads teams, manages budgets, and aligns sales and marketing effortsManages sales teams, executes marketing plans, and supports revenue targets within specific regions or products
Required CredentialsTypically requires advanced degrees (MBA, PhD), extensive industry experience, leadership skillsRequires bachelor's or master's degree, sales or marketing experience, industry knowledge
Work EnvironmentStrategic, leadership-focused, often in corporate offices or headquartersOperational, team management, often in regional offices or field settings

The main difference is that the Director Commercial Operations Biotech focuses on strategic leadership and overall commercial planning, while the Commercial Manager Biotech handles day-to-day sales and marketing execution. The director role involves higher-level decision-making and cross-department coordination, whereas the manager role is more tactical and region-specific.

What are popular job titles related to Director Commercial Operations Biotech jobs in California?

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What cities in California are hiring for Director Commercial Operations Biotech jobs?

Cities in California with the most Director Commercial Operations Biotech job openings:

Infographic showing various Director Commercial Operations Biotech job openings in California as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Director, Commercial Operations

San Francisco, CA โ€ข On-site

Crusoe
IT Servicesย โ€ขย 201 - 500 employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 6 days ago


Job description

Crusoe is on a mission to accelerate the abundance of energy and intelligence. As the only vertically integrated AI infrastructure company built from the ground up, we own and operate each layer of the stack - from electrons to tokens - to power the world's most ambitious AI workloads. When you join Crusoe, you join a team that is building the future, faster.
We're in the midst of the greatest industrial revolution of our time. The demand for AI compute is boundless, and power is a bottleneck. We're solving that - with an energy-first approach that makes AI infrastructure better for the world and faster for the people innovating with AI.
We're looking for problem-solving, opportunity-finding teammates with a sense of urgency, who believe in the scale of our ambition and thrive on a path not fully paved - people who want to grow their careers alongside a team of experts across energy, manufacturing, data center construction, and cloud services.
If you want to do the most meaningful work of your career, help our customers and partners advance their AI strategies, and be part of a high-performing team that believes in each other, come build with us at Crusoe.
About This Role
The Director, Commercial Operations will be the operational backbone of Crusoe's Energy Development Group. This person owns the analytical frameworks, pipeline processes, and team capabilities that allow Crusoe to evaluate and advance land and power opportunities at speed and at scale. From complex financial modeling and market analysis to pipeline integrity and board-level reporting, this role ensures the BD team operates with precision and strategic clarity.
This is a leadership-first, analytically grounded role. The ideal candidate brings deep experience in energy project finance or development, a track record of building and mentoring high-performing analyst teams, and the process orientation to continuously raise the quality bar on how Crusoe evaluates and advances opportunities. You will work closely with senior leadership across Energy Development, Real Estate, Finance, Cloud, Energy Innovation, Design / Engineering, Pre-Construction, and Construction teams and will be a key contributor to the operational health of Crusoe's project pipeline.
What You'll Be Working On
  • Overseeing a team of Energy Development Analysts, setting the standard for analytical rigor, process discipline, and professional growth
  • Owning the development and refinement of economic models that underpin power origination and data center site pricing decisions
  • Driving continuous improvement of due diligence workflows, pipeline management processes, and reporting mechanisms across the Energy Development team
  • Overseeing the integrity and accuracy of Crusoe's data center opportunity pipeline, ensuring leadership has a reliable, real-time view of the project portfolio
  • Supervising the creation of board-level presentations, project approval materials, and executive communications that translate analytical complexity into clear strategic recommendations
  • Tracking and synthesizing hyperscaler activity, regulatory developments, and domestic energy infrastructure trends to surface actionable intelligence for the team
  • Supporting cross-functional collaboration between Energy Development and the Real Estate, Finance, Cloud, Energy Innovation, Design / Engineering, Pre-Construction, and Construction teams to move projects efficiently through the development pipeline

Core Responsibilities
Lead and enable the Energy Development Analyst team
  • Support, mentor, and develop a team of analysts, fostering a collaborative, high-performance culture
  • Provide hands-on guidance on financial modeling, market analysis, and project evaluation

Drive analytical quality and strategic relevance
  • Oversee the development of detailed economic models for new large-scale land and power opportunities and data center site power pricing
  • Ensure analyses of energy development potential and economics are accurate, rigorous, and decision-ready
  • Guide the team in leveraging internal data analytics tools and external market intelligence to identify and vet opportunities

Own pipeline management and process improvement
  • Drive continuous improvement of business operations processes within the Energy Development team, including project management, due diligence workflows, and reporting mechanisms
  • Maintain the integrity of Crusoe's data center opportunity pipeline, ensuring data accuracy and timely updates
  • Develop and implement best practices for tracking key pipeline metrics and project statuses

Deliver executive-ready reporting and communications
  • Supervise the creation and delivery of board-level presentations, project approval materials, and ad hoc reports for senior management
  • Ensure all communications clearly articulate analytical findings, strategic implications, and support for business decisions

Support cross-functional collaboration and stakeholder engagement
  • Facilitate effective communication between the Energy Development team and the Real Estate, Finance, Cloud, Energy Innovation, Design / Engineering, Pre-Construction, and Construction teams
  • Support the team in communications with external stakeholders including developers, IPPs, and potential partners

Monitor market and regulatory intelligence
  • Oversee tracking and analysis of hyperscaler and co-located data center activity, regulatory changes in the energy sector, and domestic energy infrastructure investments
  • Ensure the team synthesizes this information to identify potential impacts and opportunities for Crusoe

Qualifications
Required
  • 7+ years of progressive experience in consulting, project finance, investment banking, private equity, energy development, or business operations, with significant focus on the energy sector (renewables, conventional power, or oil & gas)
  • 3+ years of experience in a managerial or team leadership role, with a demonstrated ability to mentor and develop direct reports
  • Deep understanding of energy markets, project economics, and financial modeling
  • Exceptional analytical, quantitative, and problem-solving skills
  • Advanced proficiency in Microsoft Excel and Google Suite; experience with pipeline management systems
  • Strong written and verbal communication skills; ability to distill complex analytical and commercial content into clear, executive-ready recommendations
  • Demonstrated ability to build and improve operational processes in a fast-moving, high-ambiguity environment
  • Bachelor's degree in Finance, Economics, Engineering, Business Administration, or a related field

Preferred
  • MBA or relevant advanced degree
  • Experience with data center infrastructure, HPC, or large-scale power-consuming industries
  • Familiarity with power purchase agreements, offtake structures, and the commercial frameworks that govern energy project development
  • Experience with or strong aptitude for leveraging AI-based tools to drive analytical efficiency and output quality
  • Ability to travel domestically as required (estimated <20%)

Benefits:
  • Competitive compensation and equity packages
  • Restricted Stock Units
  • Paid time off, paid holidays & leave of absence programs
  • Comprehensive health, dental & vision insurance
  • Employer contributions to HSA account
  • Paid parental leave
  • Paid life insurance, short-term and long-term disability
  • Professional development & tuition reimbursement
  • Mental health & wellness support
  • Commuter benefits (parking & transit)
  • Cell phone stipend
  • 401(k) Retirement plan with company match up to 4% of salary
  • Volunteer time off
  • Global travel insurance & emergency assistance
  • Daily meals allowance
  • Additional perks & programs specific to location

Compensation Range
Compensation will be paid in the range of up to $180,000 -$220,000 + Bonus. Restricted Stock Units are included in all offers. Compensation to be determined by the applicants knowledge, education, and abilities, as well as internal equity and alignment with market data.
Crusoe is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, religion, disability, genetic information, pregnancy, citizenship, marital status, sex/gender, sexual preference/ orientation, gender identity, age, veteran status, national origin, or any other status protected by law or regulation.