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Director Clinical Project Management Jobs (NOW HIRING)

PSI CRO

Clinical Project Manager

Regional clinical project management experience, including management of all project services from ... startup to closure * Therapeutic experience in Oncology, Gastroenterology, and/or ...

University of Utah

Clinical Project Managers

Campus, IL · On-site

$110 - $150/hr

Utilize project management methodologies, lead cross-functional teams, resolve issues within the ... Assume responsibility for additional assignments as directed by the Program Manager Minimum ...

Alto Neuroscience, Inc.

Clinical Project Manager

$125K - $170K/yr

Collaborate with Data Management to ensure development of CRFs and related plans for appropriate ... Manage assigned direct reports and provide oversight of their responsibilities, deliverables, and ...

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Director Clinical Project Management information

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How much do director clinical project management jobs pay per year?

As of Sep 7, 2026, the average yearly pay for director clinical project management in the United States is $124,379.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,000.00 and $147,500.00 per year, depending on experience, location, and employer.

What does a director of clinical project management do?

A Director of Clinical Project Management oversees the planning, execution, and completion of clinical trials within a pharmaceutical or biotech company. They lead project management teams, ensure regulatory compliance, manage budgets and timelines, and coordinate communication among stakeholders. Their responsibilities also include risk management, resource allocation, and ensuring trials meet both scientific and business objectives. This role is critical for bringing new medical treatments through the development pipeline to market approval.

What are some common challenges faced by a director of clinical project management, and how can they be addressed?

Directors of Clinical Project Management often encounter challenges such as managing complex, multi-site trials, maintaining regulatory compliance, and coordinating cross-functional teams. Balancing timelines, budgets, and quality expectations can also be demanding, especially when unexpected issues arise. Successful directors address these challenges by fostering clear communication, utilizing robust project management tools, and building strong relationships with stakeholders. Staying current with regulatory changes and providing mentorship to team members also helps ensure project success and professional growth.

What are the key skills and qualifications needed to thrive as a director of clinical project management, and why are they important?

To thrive as a Director of Clinical Project Management, you need deep expertise in clinical research, regulatory compliance, project leadership, and typically an advanced degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as PMP or CCRP are commonly required. Strong strategic thinking, communication, and team leadership skills help drive project success and foster collaboration among cross-functional teams. These competencies are vital for delivering clinical trials on time, within budget, and in compliance with regulatory standards.

What is the difference between Director Clinical Project Management vs Clinical Project Manager?

AspectDirector Clinical Project ManagementClinical Project Manager
ResponsibilitiesOversees multiple projects, strategic planning, team leadershipManages individual clinical trials, day-to-day operations
Experience & CredentialsTypically requires 8+ years, advanced degrees, leadership experienceUsually 3-5 years, relevant clinical or project management certifications
Work EnvironmentSenior management, cross-functional teams, strategic meetingsProject teams, site coordination, operational tasks

The main difference is that the Director Clinical Project Management holds a senior leadership role overseeing multiple projects and strategic initiatives, while the Clinical Project Manager focuses on managing individual clinical trials and operational activities. Both roles require relevant experience and certifications, but the director's scope is broader and more strategic.

How much do director clinical project managements earn?

The salary for a Director of Clinical Project Management typically ranges from $120,000 to $180,000 annually, depending on experience, location, and the size of the organization. Senior roles with extensive experience and certifications like PMP or PMI-ACP can earn higher compensation, often including bonuses and benefits.
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Director Clinical Project Management jobs near you
Infographic showing various Director Clinical Project Management job openings in the United States as of August 2026, with employment types broken down into 94% Full Time, and 6% Contract. Highlights an 78% In-person, and 22% Remote job distribution, with an average salary of $124,379 per year, or $59.8 per hour.

Senior Project Manager, Clinical Operations

Enigma Search

South San Francisco, CA • On-site

Other

Posted 17 days ago

Job description

The Sr. Project Manager, Clinical Operations is responsible for driving portfolio-level project management and operational excellence across clinical development programs. This role partners closely with Clinical Operations leadership, Study Leads, and cross-functional teams to support the successful execution of clinical pharmacology, Phase 1, Phase 2, and Phase 3 studies.

The position combines study execution oversight with leadership of strategic initiatives designed to improve Clinical Operations processes, systems, scalability, and organizational effectiveness. The successful candidate will bring structure to complex initiatives, facilitate cross-functional collaboration, manage risks and dependencies, and help enable efficient, high-quality clinical trial execution.


Key Responsibilities


Clinical Project & Portfolio Management

  • Coordinate project management activities across multiple clinical studies, ensuring alignment of timelines, milestones, risks, dependencies, and deliverables.
  • Develop and maintain project plans, dashboards, status reports, risk registers, and operational metrics.
  • Monitor portfolio progress, identify risks, and facilitate timely issue resolution.
  • Support portfolio planning, leadership reporting, and cross-functional communication.

Cross-Functional Leadership

  • Facilitate Study Execution Team (SET), governance, and operational review meetings.
  • Drive accountability for decisions, action items, and follow-up activities.
  • Partner with Clinical Science, Biometrics, Data Management, Regulatory Affairs, Clinical Supply, Quality Assurance, Finance, and other stakeholders to ensure successful study execution.

Strategic Initiatives & Operational Excellence

  • Lead cross-functional initiatives that enhance Clinical Operations capabilities, processes, and systems.
  • Manage projects such as eTMF governance, AI and automation initiatives, CDx workflows, SOP development, inspection readiness, clinical systems implementations, and process improvement programs.
  • Develop standardized tools, templates, KPIs, and best practices to improve consistency, efficiency, and scalability.
  • Support onboarding, training, change management, and continuous improvement efforts.


Qualifications

  • Bachelor's degree in Life Sciences or a related field.
  • 6-8+ years of Clinical Project Management experience and/or 8+ years in Clinical Operations, including significant biotech experience.
  • Experience managing complex cross-functional clinical development programs.
  • Strong understanding of clinical trial operations across early-stage, Phase 2, and Phase 3 studies.
  • Demonstrated ability to lead meetings, manage timelines, mitigate risks, and influence stakeholders without direct authority.
  • Experience with operational improvement initiatives, systems implementation, and change management preferred.
  • Strong communication, organization, and problem-solving skills.
  • Proficiency with project management tools and Microsoft Office applications.
  • Experience in GCP-regulated environments and familiarity with CTMS, eTMF, and EDC systems preferred.


Apply