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Director Clinical Project Management Jobs (NOW HIRING)

CTI

Clinical Project Coordinator

Raleigh, NC · On-site

Support Clinical Project Manager / Director in completing clinical project management activities; support activities throughout all phases of a clinical project, including any SOP-required ...

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How much do director clinical project management jobs pay per year?

As of Aug 17, 2026, the average yearly pay for director clinical project management in the United States is $124,379.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,000.00 and $147,500.00 per year, depending on experience, location, and employer.

What does a director of clinical project management do?

A Director of Clinical Project Management oversees the planning, execution, and completion of clinical trials within a pharmaceutical or biotech company. They lead project management teams, ensure regulatory compliance, manage budgets and timelines, and coordinate communication among stakeholders. Their responsibilities also include risk management, resource allocation, and ensuring trials meet both scientific and business objectives. This role is critical for bringing new medical treatments through the development pipeline to market approval.

What are some common challenges faced by a director of clinical project management, and how can they be addressed?

Directors of Clinical Project Management often encounter challenges such as managing complex, multi-site trials, maintaining regulatory compliance, and coordinating cross-functional teams. Balancing timelines, budgets, and quality expectations can also be demanding, especially when unexpected issues arise. Successful directors address these challenges by fostering clear communication, utilizing robust project management tools, and building strong relationships with stakeholders. Staying current with regulatory changes and providing mentorship to team members also helps ensure project success and professional growth.

What are the key skills and qualifications needed to thrive as a director of clinical project management, and why are they important?

To thrive as a Director of Clinical Project Management, you need deep expertise in clinical research, regulatory compliance, project leadership, and typically an advanced degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as PMP or CCRP are commonly required. Strong strategic thinking, communication, and team leadership skills help drive project success and foster collaboration among cross-functional teams. These competencies are vital for delivering clinical trials on time, within budget, and in compliance with regulatory standards.

What is the difference between Director Clinical Project Management vs Clinical Project Manager?

AspectDirector Clinical Project ManagementClinical Project Manager
ResponsibilitiesOversees multiple projects, strategic planning, team leadershipManages individual clinical trials, day-to-day operations
Experience & CredentialsTypically requires 8+ years, advanced degrees, leadership experienceUsually 3-5 years, relevant clinical or project management certifications
Work EnvironmentSenior management, cross-functional teams, strategic meetingsProject teams, site coordination, operational tasks

The main difference is that the Director Clinical Project Management holds a senior leadership role overseeing multiple projects and strategic initiatives, while the Clinical Project Manager focuses on managing individual clinical trials and operational activities. Both roles require relevant experience and certifications, but the director's scope is broader and more strategic.

How much do director clinical project managements earn?

The salary for a Director of Clinical Project Management typically ranges from $120,000 to $180,000 annually, depending on experience, location, and the size of the organization. Senior roles with extensive experience and certifications like PMP or PMI-ACP can earn higher compensation, often including bonuses and benefits.
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Director Clinical Project Management jobs near you
Infographic showing various Director Clinical Project Management job openings in the United States as of August 2026, with employment types broken down into 94% Full Time, and 6% Contract. Highlights an 78% In-person, and 22% Remote job distribution, with an average salary of $124,379 per year, or $59.8 per hour.

Senior Director, Clinical Project Delivery

Immunome, Inc.

Bothell, WA

Full-time

Posted 3 days ago

New

Job description

Position Overview

The Senior Director, Clinical Project Delivery (CPD) provides strategic and operational leadership for Immunome's clinical trial portfolio, overseeing all aspects of clinical trial delivery from planning and initiation through completion-ensuring studies are executed on time, within budget, and in compliance with regulatory requirements and corporate objectives.  

The person in this role will build a high-performing CPD team responsible for managing overall project delivery of Immunome's clinical trials, serving as both people leader and subject matter expert to drive consistency and operational excellence in how project delivery is executed across programs.   

The Senior Director may also be assigned to oversee one or more development programs and/or lead key projects. 

Responsibilities

Clinical Project Delivery Team Leadership and Development  

  • Establish a strategic vision for the CPD function and in partnership with Clinical Site and Trial Operations implement standards, tools, and governance needed to ensure studies are delivered on time, within scope and to quality expectations.  
  • Build, lead, and mentor a team of project delivery leads / project management leads.  
  • Design and deliver training programs on timeline management, enrollment forecasting/tracking, risk identification and trial delivery best practices. 
  • Establish onboarding curricula and ongoing capability-building for new and existing staff.  
  • Set performance expectations, conduct evaluations, and support career development and succession planning within the team.   

Project and Portfolio Delivery Oversight  

  • Own the overall framework for study-level timelines development, tracking, and reporting across the portfolio. 
  • Oversee development and maintenance of enrollment graphs and dashboards, ensuring accuracy and timely updates to inform decision-making. 
  • Monitor and manage project delivery metrics (timelines, milestones, enrollment, budget adherence, vendor KPIs) and drive corrective action when studies are at risk.  
  • Oversee CPD team performance across trials.  
  • Identify operational risks and implement mitigation strategies to ensure successful trial delivery.  

Clinical Operations Leadership  

  • Support long-term resource planning and department growth to meet the demands of a rapidly expanding clinical portfolio. 
  • Champion a culture of accountability, collaboration, and continuous improvement.  
  • Contribute to departmental strategy.  

Vendor and CRO Management  

  • Oversee relationships with external partners including CROs, central labs, and clinical service providers. 
  • Ensure vendor compliance with contractual obligations, operational timelines, and performance metrics across the portfolio.  
  • Drive governance meetings, vendor oversight, and quality management processes to ensure effective trial execution.  

Quality Assurance and Regulatory Compliance  

  • Ensure adherence to ICH-GCP, FDA, EMA, and global regulatory requirements for clinical research. 
  • Partner with Quality Assurance to ensure ongoing inspection readiness and implement corrective actions as needed. 
  • Drive operational excellence to ensure data integrity and consistent trial conduct.  

Cross-Functional Collaboration  

  • Align cross-functionally on program objectives and execution plans. 
  • Partner as needed to mitigate delivery risks.  
  • Represent Clinical Operations in governance forums and provide operational input into program and portfolio-level strategic decisions.  
  • Support regulatory submissions (INDs, NDAs, BLAs) and health authority interactions as needed.  

Budget and Resource Management   

  • Partner with Finance to oversee development, management, and forecasting of clinical trial budgets, ensuring alignment with corporate priorities and program timelines. 
  • Oversee resource allocation to optimize team performance and ensure timely delivery of all operational milestones. 
  • Maintain financial oversight for clinical trial activities, whether conducted by in-house teams or outsourced.  

Qualifications

  • Bachelor's degree with 14+ years of clinical project management experience in the biotechnology or pharmaceutical industry, or an equivalent combination of education and experience. 
  • Demonstrated experience building, training, and leading project delivery/clinical project management teams. 
  • Demonstrated expertise in study timeline development, enrollment forecasting and tracking methodologies, and trial risk management. 
  • Proven track record managing complex, multi-study portfolios in a pharmaceutical or biotech environment. 

Knowledge and Skills

  • Deep understanding of clinical development, trial design, and global regulatory frameworks (ICH-GCP, FDA, and EMA). 
  • Ability to build and lead global clinical trials across the full development lifecycle (Phase I-IV).  
  • Strong project management skills; PMP Certification preferred.  
  • Demonstrated ability to lead cross-functional initiatives and influence stakeholders at all organizational levels.  
  • Ability to build, lead, and scale high-performing CPD teams, including managing and developing people leaders.  
  • Exceptional communication, negotiation, and interpersonal skills.  
  • Analytical mindset with a strategic approach to problem-solving and decision-making.  
  • Ability to prioritize and manage multiple competing priorities in a fast-paced, dynamic environment.  
  • High degree of professionalism, adaptability, and accountability. 

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