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Director Clinical Development Jobs (NOW HIRING)

Natera

OR · On-site

The Associate Director, Clinical Development is a leadership role responsible for executing Natera's clinical development objectives. The core responsibilities of the role include outlining clinical ...

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How much do director clinical development jobs pay per year?

As of Jul 6, 2026, the average yearly pay for director clinical development in the United States is $126,639.00, according to ZipRecruiter salary data. Most workers in this role earn between $93,500.00 and $151,500.00 per year, depending on experience, location, and employer.

What does a Director of Clinical Development do?

A Director of Clinical Development oversees the planning, execution, and management of clinical trials to ensure the safety and efficacy of new therapies. They collaborate with cross-functional teams, regulatory agencies, and key stakeholders to design and implement clinical strategies. Their role includes protocol development, trial monitoring, and ensuring compliance with regulatory standards. Additionally, they analyze trial data, manage budgets, and contribute to the overall drug development process.

What are the most common challenges faced by a Director of Clinical Development?

Directors of Clinical Development often navigate challenges such as aligning multiple cross-functional teams, managing complex project timelines, and ensuring compliance with evolving regulatory standards globally. They may also need to address issues related to trial participant recruitment, data integrity, and budget management. Adapting quickly to shifting priorities while maintaining high ethical and scientific standards is crucial. Successful Directors leverage collaboration, proactive problem-solving, and their in-depth industry knowledge to overcome these challenges and deliver impactful clinical results.

What are the key skills and qualifications needed to thrive in the Director Clinical Development position, and why are they important?

A Director Clinical Development typically requires an advanced degree in life sciences or medicine, extensive experience in clinical research, and a strong understanding of regulatory guidelines. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification are highly valued. Exceptional leadership, strategic thinking, and effective cross-functional communication set outstanding candidates apart. These competencies ensure clinical programs are executed efficiently, ethically, and in alignment with organizational goals.

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Director Clinical Development jobs near you
Infographic showing various Director Clinical Development job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 90% Full Time, and 9% Part Time. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $126,639 per year, or $60.9 per hour.
Associate Director, Clinical Development

Associate Director, Clinical Development

Revolution Medicines

Redwood City, CA • Hybrid

Other

Posted yesterday

Job description

The Opportunity:

We are seeking an experienced clinical scientist to serve as Associate Director, Clinical Science in support of Revolution Medicines' late-stage clinical programs.  In this role, you will independently lead defined clinical science workstreams within pivotal and supportive studies and support execution of the registrational clinical development strategy for assigned molecule(s) and indication(s). The Associate Director plays a critical role in ensuring high-quality clinical data review, protocol consistency, and submission-readiness for late-stage programs. This position operates with substantial autonomy within assigned scope and collaborates closely with more senior clinical science team members and the study Medical Director to ensure medically sound and regulatory-aligned execution. Furthermore:

  • Independently lead defined clinical science workstreams within pivotal and registration-enabling studies (e.g., endpoint strategy, data review oversight, CSR section ownership, data consistency initiatives).

  • Contribute substantially to protocol development, CRF design, ICF updates, and alignment of data standards with downstream regulatory requirements.

  • Drive ongoing clinical data review activities, including plausibility review, query trend analysis, and preparation for database lock.

  • Accountable for assigned clinical science deliverables supporting regulatory submissions, including CSR sections, briefing package content, and health authority response inputs.

  • Support preparation of regulatory documentation and responses to health authority questions.

  • Collaborate closely with Biostatistics, Data Management, Medical Writing, Medical Directors, Pharmacovigilance, and Clinical Operations to ensure alignment and submission readiness.

  • Participate in study team meetings and represent Clinical Science in sub-team discussions.

  • May serve as Clinical Science lead for smaller or supportive studies, based on experience and study complexity.

  • Mentor Senior Clinical Scientists and Clinical Scientists as appropriate.

  • Proactively identify risks, propose mitigation strategies, and escalate significant issues as appropriate to Directors or Senior Directors.

  • Contribute to cross-functional discussions to support eSective and eSicient study execution.

Required Skills, Experience and Education:

  • Bachelor's Degree (life sciences preferred); Advanced Clinical/Science Degree is a plus (e.g., PharmD, PhD, MSN, MPH, etc.).

  • 5+ years of clinical development or relevant experience within a pharmaceutical, biotech, or academic clinical research setting; late-stage development experience preferred.

  • Demonstrated experience contributing to pivotal or registration-enabling studies.

  • Strong knowledge of GCP, ICH, FDA, EMA, and other relevant regulatory guidelines.

  • Experience contributing to protocol development, CRF design, and regulatory documentation.

  • Strong analytical skills and experience interpreting clinical trial data.

  • Proven ability to work eSectively in cross-functional teams and integrate multiple perspectives.

  • Excellent written and verbal communication skills.

  • Strong organizational skills and ability to manage multiple deliverables.

Preferred Skills:

  • Experience contributing to NDA/BLA/MAA submission components.

  • Experience supporting health authority interactions.

  • Demonstrated ability to lead defined study-level initiatives.

  • Experience mentoring junior clinical science staffs.

#LI-Hybrid  #LI-SH1

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