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Contract Clinical Trial Manager Jobs (NOW HIRING)

Frontier Medicines

Clinical Trial Manager

Boston, MA · On-site

$120K - $150K/yr

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

Verastem

Clinical Trial Manager

Boston, MA · On-site

$100K - $125K/yr

Negotiate master service agreements, work orders, contracts, and amendments for sites/vendors ... Manager to discuss overall clinical trial(s) plans, update forecasting, and identify potential ...

Frontier Medicines

Clinical Trial Manager

Boston, MA · On-site

$120K - $150K/yr

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

CareDx, Inc.

Clinical Trial Manager

Brisbane, CA · Remote

The Clinical Trial Manager (CTM) is responsible for the management of clinical trials from study ... Conduct internal review of investigator contracts and payments, as necessary. * Provide cross ...

Alpha-9 Oncology

Clinical Trial Manager

Boston, MA · On-site

Manage day-to-day relationships with clinical trial vendors, including tracking vendor contracts, budgets, invoices, and payments against contracted scope of work, and escalating issues or variances ...

Alpha-9 Oncology

Clinical Trial Manager

Boston, MA · On-site

Manage day-to-day relationships with clinical trial vendors, including tracking vendor contracts, budgets, invoices, and payments against contracted scope of work, and escalating issues or variances ...

CareDx, Inc.

Clinical Trial Manager

Brisbane, CA · On-site

The Clinical Trial Manager (CTM) is responsible for the management of clinical trials from study ... Conduct internal review of investigator contracts and payments, as necessary. * Provide cross ...

Galderma

Senior Clinical Trial Manager

Boston, MA

$110K - $135K/yr

As applicable, provide oversight to Clinical Research Associates and Clinical Trial Administrators assigned to the clinical trial Manage Contract Research Organizations (CROs) and Functional Service ...

Vor Bio

Senior/Clinical Trial Manager (CTM)

Boston, MA

$175K - $195K/yr

Vor Biopharma is seeking a Clinical Trial Manager/Sr. Clinical Trial Manager who will be ... Participate in the selection, training, and evaluation of study personnel (contract and internal ...

Abbott

Clinical Trial Manager

Madison, WI · On-site +1

Oversee site contracting and study budget management including facilitation of site contract and ... management or lead clinical trial manager. * Uphold company mission and values through ...

Climb Bio

Clinical Trial Manager

Wellesley Hills, MA · On-site

$132K - $175K/yr

We are seeking a self-motivated Clinical Trial Manager to lead end-to-end delivery of clinical trials, with immediate emphasis on owning Phase 1 execution and supporting Phase 2 execution. Reporting ...

Shifamed

Sr. Clinical Trial Manager

Los Gatos, CA · On-site

The Sr. Clinical Trial Manager (Sr. CTM) is a hands-on program owner responsible for the end-to-end ... Oversee monitoring performed by CROs and contract CRAs; review monitoring reports, resolve site ...

Collabera

Clinical Trial Manager

Jersey City, NJ

Knowledge and experience in clinical study budgeting including timeline and the application of clinical trial performance metrics. Demonstrated ability to support the development and management of ...

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

The Clinical Trial Manager (CTM) is responsible for managing various aspects of clinical trials including study start-up, site management and monitoring activities. This includes vendor management ...

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How much do contract clinical trial manager jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for contract clinical trial manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

What is a contract clinical trial manager?

A Contract Clinical Trial Manager is a professional who oversees the planning, execution, and management of clinical trials for pharmaceutical, biotech, or medical device companies on a contractual basis. Unlike full-time employees, contract clinical trial managers are typically hired for specific projects or time periods to ensure compliance with regulatory requirements, manage study timelines, and coordinate with cross-functional teams. Their responsibilities include supervising site selection, budget management, and ensuring data quality and patient safety throughout the trial. They play a crucial role in bringing new treatments to market by ensuring trials are conducted efficiently and ethically.

What are the key skills and qualifications needed to thrive as a contract clinical trial manager?

To thrive as a Contract Clinical Trial Manager, you need expertise in clinical research processes, project management, regulatory compliance, and a degree in life sciences or related field. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications such as ACRP or SOCRA are commonly required. Excellent organizational skills, attention to detail, and strong communication enable effective coordination with sponsors, sites, and cross-functional teams. These skills ensure clinical trials meet regulatory standards, timelines, and quality benchmarks critical for successful drug development.

What are some common challenges faced by contract clinical trial managers, and how can they be effectively addressed?

Contract Clinical Trial Managers often navigate challenges such as coordinating multiple stakeholders, adhering to tight timelines, and managing protocol deviations across diverse research sites. To address these, strong communication skills and proactive project management are essential. Developing clear processes for documentation, regular team check-ins, and maintaining flexibility help ensure that trials remain compliant and on schedule. Additionally, leveraging technology for real-time data tracking can streamline collaboration and issue resolution.

What is the difference between Contract Clinical Trial Manager vs Clinical Research Associate?

AspectContract Clinical Trial ManagerClinical Research Associate
CredentialsTypically requires a Bachelor's degree in life sciences, clinical research certification preferredUsually holds a Bachelor's degree in life sciences or related field, with some certifications
Work EnvironmentManages multiple trials, oversees teams, often works remotely or on-site at trial locationsMonitors clinical sites, ensures protocol compliance, works primarily on-site at trial locations
Employer & Industry UsageHired by pharmaceutical companies, CROs, or biotech firms for trial managementEmployed by sponsors or CROs to monitor and support clinical sites

The Contract Clinical Trial Manager focuses on overseeing entire clinical trials, managing teams, and ensuring trial milestones are met. In contrast, the Clinical Research Associate primarily monitors clinical sites to ensure compliance and data integrity. Both roles require similar educational backgrounds but differ in scope and responsibilities within the clinical research process.

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Contract Clinical Trial Manager jobs near you
Infographic showing various Contract Clinical Trial Manager job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

Clinical Trial Manager

Frontier Medicines

Boston, MA • On-site

$120K - $150K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 6 days ago

Job description

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance of our Director/Sr. Director, Clinical Operations, you will serve as a key operational contact for our CROs and trial sites, helping drive feasibility assessments, site selection, start-up, maintenance, and close-out.
This is a great opportunity for someone who wants hands-on ownership of trial execution at a growing, clinical-stage biotech, with direct exposure to program strategy and cross-functional leadership. This is a hybrid role based in our Boston, MA office, with an expectation of 2-3 days per week onsite, plus periodic travel to trial sites and CRO/vendor meetings as needed.
Requirements
What will you be doing?
• Support day-to-day activities within one or more clinical trials, including country/site feasibility assessments, site selection, start-up, maintenance, and close-out.
• Serve as a key operational point of contact for CROs and trial sites, identifying and escalating potential issues as needed.
• Assist with oversight of CRO and vendor set-up, liaising with CROs to ensure timely study initiation.
• Review site-level regulatory documents (e.g., Informed Consent Forms, essential documents) and escalate to appropriate stakeholders as needed.
• Help ensure inspection readiness, TMF quality, and adherence to protocol and regulatory requirements.
• Proactively identify potential operational challenges and, in partnership with senior team members, propose mitigation plans to keep study execution on track.
• Assist with review of protocols, master template informed consent forms, case report forms, and other clinical study documents as needed.
• Monitor study performance metrics, timelines, and deliverables, and review CRO trip reports for trends and quality issues.
• Track study budgets and vendor invoices/change orders in partnership with Clinical Operations and Finance, flagging discrepancies as needed.
• Help maintain timely and accurate study registration and updates on ClinicalTrials.gov and other applicable registries.
• Coordinate Clinical Trial Team meetings and drive action item follow-up.
• Maintain clinical operations trackers, databases, and document repositories.
• Provide regular study updates to internal stakeholders and support enrollment, database lock, and study closeout activities.
Traits we believe make a strong candidate:
• Bachelor's degree in a scientific, healthcare, or related field, or an RN, required.
• 3-4 years of Clinical Trial Manager or Clinical Project Management experience, ideally supporting oncology clinical trials.
• Experience supporting oncology studies strongly preferred.
• Vendor and CRO management experience.
• Strong working knowledge of ICH-GCP guidelines and clinical trial regulations.
• Excellent organizational, problem-solving, and time management skills, with strong attention to detail.
• Strong written and verbal communication skills with a collaborative, team-oriented approach.
• Comfortable in a fast-paced, dynamic environment; a proactive, roll-up-your-sleeves mindset.
• Legally authorized to work in the United States.
Benefits
  • Health Care Plan (Medical, Dental & Vision)
  • Retirement Plan (401k, IRA)
  • Life Insurance (Basic, Voluntary & AD&D)
  • Paid Time Off (Vacation, Sick & Public Holidays)
  • Family Leave (Maternity, Paternity)
  • Short Term & Long Term Disability
  • Training & Development
  • Free Food & Snacks
  • Wellness Resources
  • Stock Option Plan

At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $120,000 - $150,000 Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.
This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.

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