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$50.5K

$111.3K

$137.5K

How much do computational scientist jobs pay per year?

As of Sep 2, 2026, the average yearly pay for computational scientist in the United States is $111,343.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $137,000.00 per year, depending on experience, location, and employer.

What is a computational scientist?

A Computational Scientist uses advanced computing techniques, algorithms, and simulations to solve complex scientific and engineering problems. They work across various fields, such as physics, biology, chemistry, and engineering, developing models and running simulations to analyze large datasets. Their role often involves programming, data analysis, and collaboration with domain experts to gain insights and make predictions.

What does a computational scientist do?

A typical day for a Computational Scientist may involve developing and running computer simulations, analyzing large datasets, or creating algorithms to address complex scientific problems. You might spend time coding, troubleshooting computational models, collaborating with researchers or engineers, and documenting your findings. The work often involves both independent problem-solving and teamwork within multidisciplinary groups. Additionally, presenting results, preparing research papers, or contributing to grant proposals could be regular tasks, depending on your specific employer and industry. This dynamic role offers a blend of technical challenges and opportunities for innovation.

What skills and qualifications are needed to thrive as a computational scientist?

To thrive as a Computational Scientist, you need strong analytical skills, advanced knowledge of mathematics and computer science, and typically a graduate degree in a quantitative field such as physics, engineering, or computer science. Familiarity with programming languages like Python, R, or C++, experience with high-performance computing, and tools such as MATLAB or scientific visualization software are vital. Excellent problem-solving abilities, collaboration, and effective communication skills make someone stand out in this position. These skills are crucial for developing models, analyzing complex data, and communicating scientific insights to interdisciplinary teams.

What are the career paths in computational science?

Computational scientists can pursue career paths in academia, industry, or government research, often specializing in areas like data analysis, modeling, or simulation. They may advance to senior scientist, research director, or interdisciplinary roles, and typically develop skills in programming, statistical analysis, and domain-specific knowledge. Certifications in programming languages or data management can enhance career progression.
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Computational Scientist jobs near you
Infographic showing various Computational Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 91% Full Time, 4% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $111,343 per year, or $53.5 per hour.

Computational Scientist (Functional Genomics) - Remote

Astrix Inc

South San Francisco, CA • On-site, Remote

$35 - $40/hr

Full-time, Contractor

Re-posted 11 days ago

Job description

Pay Rate Low: 35 | Pay Rate High: 40
Our client is an innovative biotechnology company seeking a Computational Scientist to support advanced research initiatives focused on analyzing large-scale single-cell perturbation datasets.
Title: Computational Scientist - Single-Cell Genomics & Perturbation Biology
Location: Remote (Must be open to working PST)
Schedule: Full-Time (40 hours/week)
Duration: 12-Month Contract (+Benefits)
Pay rate: $35-40/hr
In this role, you will leverage computational approaches to generate biological insights that accelerate target identification, drug discovery, and the development of next-generation therapeutics. This role will partner with cross-functional teams of computational scientists, biologists, and data scientists to generate biological insights from high-content sequencing data while contributing to scalable computational pipelines and best practices.
Key Responsibilities
  • Analyze large-scale perturbation sequencing datasets (e.g., Perturb-seq, CROP-seq, multi-condition single-cell RNA-seq).
  • Develop and apply computational methods to generate insights that support early-stage therapeutic research.
  • Collaborate with interdisciplinary teams across computational biology, biology, chemistry, and data science.
  • Contribute to software, analysis pipelines, and workflow improvements for large-scale genomic data analysis.
  • Present findings and communicate complex analyses to technical and non-technical stakeholders.

Qualifications
  • Master's or PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Mathematics, or a related quantitative life science field.
  • 1-3+ years of relevant industry or postdoctoral experience.
  • Hands-on experience analyzing Perturb-seq, CROP-seq, SciPlex, or other multi-condition single-cell RNA-seq datasets.
  • Strong programming skills in Python and/or R.
  • Experience working in HPC environments (SLURM, AWS, SGE, or similar).
  • Must be authorized to work in the United States without sponsorship.
  • Knowledge of workflow management tools such as Nextflow or Snakemake is preferred.
  • Strong software engineering fundamentals and experience with version control.
  • Excellent analytical, problem-solving, and communication skills.

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