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Senior Bioinformatics Scientist Jobs (NOW HIRING)

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to early cancer detection. As a core member of the Research and Development department, you will play a ...

Natera

OR · On-site

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to early cancer detection. As a core member of the Research and Development department, you will play a ...

Foundation Medicine

Sr. Bioinformatics Scientist

Boston, MA · Hybrid

$145K - $170K/yr

The Senior Bioinformatics Scientist is responsible for supporting novel biomarker definition, biomarker analysis, development, and validation for FMI CDx programs. The incumbent mentors or supervises ...

BeiGene USA

Senior Scientist, Bioinformatics

San Carlos, CA

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are seeking a highly motivated and experienced Senior Bioinformatics Scientist to join our Translational Discovery, Research, and Medicine team in San Carlos, California. This individual will play ...

AA2IT

Bioinformatics Scientist - II

Cambridge, MA

$75/hr

Senior Bioinformatics Scientist Location: Cambridge, MA Pay Rate: $75/HR - 100/HR Must Have Education: * Ph.D. in Computational Biology or closely related field -- no BS/MS-only candidates will be ...

AA2IT

Bioinformatics Scientist - II

Cambridge, MA

$75/hr

Senior Bioinformatics Scientist Location: Cambridge, MA Pay Rate: $75/HR - 100/HR Must Have Education: * Ph.D. in Computational Biology or closely related field -- no BS/MS-only candidates will be ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CA Job Type: Full-time ( Hybrid ) Equity: Highly Competitive Equity About Our Client ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CA Job Type: Full-time ( Hybrid ) Equity: Highly Competitive Equity About Our Client ...

Vivo HealthStaff

Bioinformatics Scientist

Ann Arbor, MI · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CA Job Type: Full-time ( Hybrid ) Equity: Highly Competitive Equity About Our Client ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CA Job Type: Full-time ( Hybrid ) Equity: Highly Competitive Equity About Our Client ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CAJob Type: Full-time (Hybrid)Equity: Highly Competitive Equity About Our ClientTechStaffers has ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CA Job Type: Full-time ( Hybrid ) Equity: Highly Competitive Equity About Our Client ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CAJob Type: Full-time (Hybrid)Equity: Highly Competitive Equity About Our ClientTechStaffers has ...

Vivo HealthStaff

Bioinformatics Scientist

Ann Arbor, MI · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San Francisco, CAJob Type: Full-time (Hybrid)Equity: Highly Competitive Equity About Our ClientTechStaffers has ...

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Senior Bioinformatics Scientist information

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How much do senior bioinformatics scientist jobs pay per year?

As of Aug 13, 2026, the average yearly pay for senior bioinformatics scientist in the United States is $101,443.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $137,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior bioinformatics scientist?

To thrive as a Senior Bioinformatics Scientist, you need expertise in computational biology, data analysis, and molecular biology, typically with an advanced degree such as a PhD in bioinformatics, computational biology, or a related field. Familiarity with programming languages (such as Python, R), bioinformatics pipelines, databases, and experience with high-performance computing environments is crucial. Strong problem-solving skills, effective communication, and the ability to lead cross-disciplinary teams are key soft skills in this role. These abilities ensure accurate data interpretation, successful project collaboration, and advancement of scientific research initiatives.

What does a senior bioinformatics scientist do?

A Senior Bioinformatics Scientist analyzes complex biological data using computational tools and algorithms, often focusing on genomics, proteomics, or transcriptomics. They design and implement bioinformatics pipelines, develop software solutions, and collaborate with biologists to interpret results. Their role includes managing large datasets, optimizing data processing workflows, and contributing to scientific publications. Additionally, they may mentor junior scientists and lead research projects to advance biological discoveries.

More about Senior Bioinformatics Scientist jobs
What cities are hiring for Senior Bioinformatics Scientist jobs? Cities with the most Senior Bioinformatics Scientist job openings:
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Senior Bioinformatics Scientist jobs near you
Infographic showing various Senior Bioinformatics Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 87% Full Time, 7% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $101,443 per year, or $48.8 per hour.

Senior Bioinformatics Scientist

Natera

San Carlos, CA • On-site

Full-time

Posted 12 days ago

Natera rating

7.6

Company rating: 7.6 out of 10

Based on 37 frontline employees who took The Breakroom Quiz

59th of 120 rated laboratories

Job description

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to early cancer detection. As a core member of the Research and Development department, you will play a pivotal role in designing and implementing innovative computational solutions. The ideal candidate possesses a robust background in algorithm development, high-throughput biological data analysis, and scalable pipeline architecture. We are looking for a versatile professional capable of thriving as an individual contributor, a collaborative co-developer, and a key participant in large-scale, cross-departmental initiatives. In this role, you will develop novel algorithms and pipelines while analyzing complex genomic datasets to advance the frontiers of early-stage cancer diagnostics.
PRIMARY RESPONSIBILITIES:

  • Innovate, design, develop, and validate advanced algorithms and statistical models to extract actionable insights from large-scale genomic datasets for early cancer detection.
  • Co-architect, implement, and deploy automated analysis workflows for clinical diagnostics, ensuring robust performance for variant calling, fusion detection, and automated quality control.
  • Contribute to rigorous code reviews, maintain comprehensive technical documentation, and drive the continuous optimization of core computational infrastructure.
  • Analyze complex multi-omic data using high-performance internal pipelines, collaborating closely with wet-lab scientists and statisticians to meet critical research milestones.

QUALIFICATIONS:

  • PhD in Bioinformatics, Computer Science, Engineering, Statistics, Cancer Biology or similar field
  • 0-3 years of professional or postgraduate experience in bioinformatics or computational biology.

KNOWLEDGE, SKILLS AND ABILITIES:

  • Excellent communication skills with a demonstrated ability to present complex computational findings to diverse cross-functional stakeholders.
  • Deep expertise in high-throughput DNA sequencing (NGS) analysis, including sequence alignment, mapping, and clinical-grade variant calling.
  • A proven track record of developing state-of-the-art, high-impact bioinformatics methodologies.
  • Advanced knowledge of data structures, algorithm design, and computational complexity analysis.
  • High proficiency in Python and its scientific ecosystem (NumPy, Pandas, Scikit-learn) for data manipulation and automation.
  • Experience with workflow orchestration languages (WDL preferred) for building and versioning scalable bioinformatics pipelines.
  • Experience with cloud-based distributed computing environments, specifically AWS.
  • Familiarity with contemporary analytical techniques and biomarkers in cancer biology.
  • Working knowledge of public genomic databases such as TCGA, COSMIC, or OncoKB.
  • Proficiency in Linux environments, including command-line tools and shell scripting.

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